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The imputation of missing values in multivariate time series (MTS) data is critical in ensuring data quality and producing reliable data-driven predictive models. Apart from many statistical approaches, a few recent studies have proposed…

Machine Learning · Computer Science 2023-05-17 Maksims Kazijevs , Manar D. Samad

Binary similarity analysis determines if two binary executables are from the same source program. Existing techniques leverage static and dynamic program features and may utilize advanced Deep Learning techniques. Although they have…

Software Engineering · Computer Science 2023-08-31 Xiangzhe Xu , Zhou Xuan , Shiwei Feng , Siyuan Cheng , Yapeng Ye , Qingkai Shi , Guanhong Tao , Le Yu , Zhuo Zhang , Xiangyu Zhang

Predictive mean matching (PMM) is a popular imputation strategy that imputes missing values by borrowing observed values from other cases with similar expectations. We show that, unlike other imputation strategies, PMM is not guaranteed to…

Methodology · Statistics 2025-07-01 Paul T. von Hippel

Missing values in electronic health record (EHR) data pose a significant challenge for epidemiologic research. Traditional methods for handling missing data, like mean imputation, may introduce bias. Multiple imputation (MI) offers a…

In medical domain, data features often contain missing values. This can create serious bias in the predictive modeling. Typical standard data mining methods often produce poor performance measures. In this paper, we propose a new method to…

Machine Learning · Statistics 2015-03-24 Talayeh Razzaghi , Oleg Roderick , Ilya Safro , Nick Marko

Causal discovery algorithms estimate causal graphs from observational data. This can provide a valuable complement to analyses focussing on the causal relation between individual treatment-outcome pairs. Constraint-based causal discovery…

Methodology · Statistics 2021-08-31 Janine Witte , Ronja Foraita , Vanessa Didelez

In many empirical settings, directly observing a treatment variable may be infeasible although an error-prone surrogate measurement of the latter will often be available. Causal inference based solely on the surrogate measurement is…

Methodology · Statistics 2024-09-26 Ying Zhou , Eric Tchetgen Tchetgen

Multiple imputation has become one of the standard methods in drawing inferences in many incomplete data applications. Applications of multiple imputation in relatively more complex settings, such as high-dimensional clustered data, require…

Methodology · Statistics 2025-04-08 Qiushuang Li , Recai Yucel

In clinical trials, mixed effects models for repeated measures (MMRM) and pattern mixture models (PMM) are often used to analyze longitudinal continuous outcomes. We describe a simple missing data imputation algorithm for the MMRM that can…

Methodology · Statistics 2016-10-13 Yongqiang Tang

Clinical decision support using data mining techniques offers more intelligent way to reduce the decision error in the last few years. However, clinical datasets often suffer from high missingness, which adversely impacts the quality of…

Machine Learning · Computer Science 2020-11-20 Xuetong Wu , Hadi Akbarzadeh Khorshidi , Uwe Aickelin , Zobaida Edib , Michelle Peate

This paper addresses patient heterogeneity associated with prediction problems in biomedical applications. We propose a systematic hypothesis testing approach to determine the existence of patient subgroup structure and the number of…

Methodology · Statistics 2021-01-08 Xu Gao , Weining Shen , Jing Ning , Ziding Feng , Jianhua Hu

Propensity score matching (PSM) has been widely used to mitigate confounding in observational studies, although complications arise when the covariates used to estimate the PS are only partially observed. Multiple imputation (MI) is a…

Applications · Statistics 2021-07-22 Albee Y. Ling , Maria E. Montez-Rath , Maya B. Mathur , Kris Kapphahn , Manisha Desai

Pre-symptomatic (or Preclinical) Alzheimer's Disease is defined by biomarker evidence of fibrillar amyloid beta pathology in the absence of clinical symptoms. Clinical trials in this early phase of disease are challenging due to the slow…

Applications · Statistics 2020-03-10 Dan Li , Samuel Iddi , Paul S. Aisen , Wesley K. Thompson , Michael C. Donohue

For a medical diagnosis, health professionals use different kinds of pathological ways to make a decision for medical reports in terms of patients medical condition. In the modern era, because of the advantage of computers and technologies,…

Machine Learning · Statistics 2021-06-08 Fahad B. Mostafa , Md Easin Hasan

Missing values pose a persistent challenge in modern data science. Consequently, there is an ever-growing number of publications introducing new imputation methods in various fields. While many studies compare imputation approaches, they…

Computation · Statistics 2025-11-10 Krystyna Grzesiak , Christophe Muller , Julie Josse , Jeffrey Näf

Prediction Rule Ensembles (PREs) are robust and interpretable statistical learning techniques with potential for predictive analytics, yet their efficacy in the presence of missing data is untested. This study uses multiple imputation to…

Applications · Statistics 2024-10-22 Vincent Schroeder , Jakob Schwerter , Marjolein Fokkema , Philipp Doebler

Data harmonization is the process by which an equivalence is developed between two variables measuring a common trait. Our problem is motivated by dementia research in which multiple tests are used in practice to measure the same underlying…

Methodology · Statistics 2021-10-13 Steven Wilkins-Reeves , Yen-Chi Chen , Kwun Chuen Gary Chan

Imputation of missing attribute values in medical datasets for extracting hidden knowledge from medical datasets is an interesting research topic of interest which is very challenging. One cannot eliminate missing values in medical records.…

Databases · Computer Science 2016-03-11 Yelipe UshaRani , P. Sammulal

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Artificial Intelligence · Computer Science 2026-01-30 Abhijith Shaji , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Greg Ver Steeg , Paul M. Thompson , Jose-Luis Ambite

Machine learning techniques typically applied to dementia forecasting lack in their capabilities to jointly learn several tasks, handle time dependent heterogeneous data and missing values. In this paper, we propose a framework using the…

Machine Learning · Statistics 2022-01-14 Carlos Sevilla-Salcedo , Vandad Imani , Pablo M. Olmos , Vanessa Gómez-Verdejo , Jussi Tohka