Related papers: Design of a System for Analyzing Cell Mechanics
Alignment-based optically pumped magnetometers (OPMs) are capable of measuring oscillating magnetic fields with high sensitivity in the fT/sqrt(Hz) range. Until now, alignment-based magnetometers have only used paraffin-coated vapour cells…
Spectroscopy is a powerful tool to probe physical, chemical, and biological systems. Recent advances in microfabrication have introduced novel, intriguing mesoscopic quantum systems including superconductor-semiconductor hybrid devices and…
This paper introduces an innovative two-core fiber (TCF) optic sensor employing a Mach-Zehnder interferometer (MZI) to monitor the optogenetic response of light-sensitive human dental pulp stem cells (hDPSCs). The in-fiber MZI, formed using…
We report a laser noise reduction method by locking it to an actively stabilized fiber-based Mach Zehnder interferometer with 10 km optical fiber to achieve large arm imbalance. An acousto optic modulator is used for interferometer…
Serial section electron microscopy (ssEM) is a widely used technique for obtaining volumetric information of biological tissues at nanometer scale. However, accurate 3D reconstructions of identified cellular structures and volumetric…
Accelerometers offer motion sensing capabilities across a wide range of areas, enabling navigational awareness in consumer goods and defense applications, and playing a key role in monitoring and control systems. To date, on-chip…
Solid stress is increasingly being recognized as a key driver of tumor progression and aggressiveness, yet it has not been directly measured in patients so far. Here, we combine multifrequency magnetic resonance elastography with 3D…
The mechanical properties of PC12 living cells have been studied at the nanoscale with a Force Feedback Microscope using two experimental approaches. Firstly, the local mechanical impedance of the cell membrane has been mapped…
Accurate position and posture measurements of the freely-falling test mass are crucial for the success of spaceborne gravitational wave detection missions. This paper presents a novel laboratory-developed test mass motion readout that…
Nanomechanical oscillators have been employed as transducers to measure force, mass and charge with high sensitivity. They are also used in opto- or electromechanical experiments with the goal of quantum control and phenomena of mechanical…
Double-slit electron interferometers, fabricated in high mobility two-dimensional electron gas (2DEG), proved to be very powerful tools in studying coherent wave-like phenomena in mesoscopic systems. However, they suffer from small fringe…
Interferometry techniques are essential for extracting phase information from optical systems, enabling precise measurements of dispersion and highly sensitive detection of perturbations. While phase sensing offers enhanced sensitivity…
Real-time monitoring of dynamic biological processes in the body is critical to understanding disease progression and treatment response. This data, for instance, can help address the lower than 50% response rates to cancer immunotherapy.…
The ability to probe a materials electromechanical functionality on the nanoscale is critical to applications from energy storage and computing to biology and medicine. Voltage modulated atomic force microscopy (VM-AFM) has become a…
The ever-increasing demand for high-capacity rechargeable batteries highlights the need for sensitive and accurate diagnostic technology for determining the state of a cell, for identifying and localizing defects, or for sensing capacity…
Polymeric materials are widely used in industries ranging from automotive to biomedical. Their mechanical properties play a crucial role in their application and function and arise from the nanoscale structures and interactions of their…
We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model,…
We show that the atomic force microscope can perform stress relaxation and creep compliance measurements on living cells. We propose a method to obtain the mechanical properties of the studied biomaterial: the relaxation time, the elastic…
High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…
Acoustic holography in the megahertz frequency range can impact numerous applications, including manufacturing, non-destructive testing, and transcranial ultrasound. However, designing lens topologies for complex acoustic holograms in the…