Related papers: Design of a System for Analyzing Cell Mechanics
Acoustical tweezers open major prospects in microbiology for cells and microorganisms contactless manipulation, organization and mechanical properties testing since they are biocompatible, label-free and can exert forces several orders of…
Patch-clamp technique is the gold standard for cellular electrophysiological measurements, which is capable of measuring single ion transport events across the cell membrane. However, the measurement possesses significant complexity, and it…
In this work, a novel approach for the detection and localisation of nonlinear guided waves often associated with the presence of damage in structural components is proposed. The method is active and consists of a piezoelectric transducer…
The energy range of hard X-rays is a key waveband to the study of high energy processes in celestial objects, but still remains poorly explored. In contrast to direct imaging methods used in the low energy X-ray and high energy gamma-ray…
Microfluidics offer remarkable flexibility for in-flow analyte characterization and can even measure the mechanical properties of biological cells through the application of hydrodynamic forces. In this work, we present a new approach to…
Optical whispering gallery mode microcavity acoustic sensors have emerged significant potential in high-sensitivity acoustic signal detection, but the narrow dynamic range limits the application prospect. To address the challenge, we…
We use a novel scanning electron Mach-Zehnder interferometer constructed in a conventional transmission electron microscope to perform inelastic interferometric imaging with free electrons. An electron wave function is prepared in two paths…
An accurate determination of specimen thickness is essential for quantitative analytical electron microscopy. Here we demonstrate that a position-averaged incoherent bright-field signal recorded on an absolute scale can be used to determine…
Comb-based optical arbitrary waveform measurement (OAWM) techniques can overcome the bandwidth limitations of conventional coherent detection schemes and may have disruptive impact on a wide range of scientific and industrial applications.…
Atomic force microscopes have proved to be fundamental research tools in many situations where a gentle imaging process is required, and in a variety of environmental conditions, such as the study of biological samples. Among the possible…
To understand cell migration, it is crucial to gain knowledge on how cells exert and integrate forces on/from their environment. A quantity of prime interest for biophysicists interested in cell movements modeling is the intracellular…
Atomic force microscopy (AFM) has been constantly supporting nanosciences and nanotechnologies for over 30 years, being present in many fields from condensed matter physics to biology. It enables measuring very weak forces at the nanoscale,…
A high sensitivity force sensor based on dielectric microspheres in vacuum, optically trapped by a single, upward-propagating laser beam, is described. Off-axis parabolic mirrors are used both to focus the 1064~nm trapping beam and to…
Cell injection is a technique in the domain of biological cell micro-manipulation for the delivery of small volumes of samples into the suspended or adherent cells. It has been widely applied in various areas, such as gene injection,…
Stable narrow-linewidth light sources play a significant role in many precision optical systems. Electro-optic laser frequency stabilization systems, such as the well-known Pound-Drever-Hall (PDH) technique, have been key components of…
We experimentally realized a new method for transmitting quantum information reliably through paired optical polarization-maintaining (PM) fibers. The physical setup extends the use of a Mach-Zehnder interferometer, where noises are…
Cells actively probe and respond to the stiffness of their surroundings. Since mechanosensory cells in connective tissue are surrounded by a disordered network of biopolymers, their in vivo mechanical environment can be extremely…
The multi-wavelength anomalous diffraction (MAD) method is used to determine phase information in x-ray crystallography by employing dispersion corrections from heavy atoms on coherent x-ray scattering. X-ray free-electron lasers (FELs)…
Optical sensing is one of the key-enablers of modern diagnostics. Especially label-free imaging modalities hold great promise as they eliminate labeling procedures prior to analysis. However, scattering signals of nanometric particles scale…
We demonstrate an optomechanical phase shifter. By electrostatically deflecting the nanofabricated mechanical structure, the effective index of a nearby waveguide is changed and the resulting phase shift is measured using an integrated…