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In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

Computation and Language · Computer Science 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

The recent development of high-throughput sequencing creates a large collection of multi-omics data, which enables researchers to better investigate cancer molecular profiles and cancer taxonomy based on molecular subtypes. Integrating…

Genomics · Quantitative Biology 2024-01-25 Bingjun Li , Sheida Nabavi

Using natural language processing (NLP) technologies to develop medical chatbots makes the diagnosis of the patient more convenient and efficient, which is a typical application in healthcare AI. Because of its importance, lots of research…

Computation and Language · Computer Science 2023-12-06 Ke Liang , Sifan Wu , Jiayi Gu

Accurate prediction of treatment outcomes in lung cancer remains challenging due to the sparsity, heterogeneity, and contextual overload of real-world electronic health data. Traditional models often fail to capture semantic information…

Based on a weighted knowledge graph to represent first-order knowledge and combining it with a probabilistic model, we propose a methodology for the creation of a medical knowledge network (MKN) in medical diagnosis. When a set of symptoms…

Artificial Intelligence · Computer Science 2017-03-29 Jingchi Jiang , Chao Zhao , Yi Guan , Qiubin Yu

The problem of answering questions using knowledge from pre-trained language models (LMs) and knowledge graphs (KGs) presents two challenges: given a QA context (question and answer choice), methods need to (i) identify relevant knowledge…

Computation and Language · Computer Science 2022-12-14 Michihiro Yasunaga , Hongyu Ren , Antoine Bosselut , Percy Liang , Jure Leskovec

The study of cellular signalling pathways and their deregulation in disease states, such as cancer, is a large and extremely complex task. Indeed, these systems involve many parts and processes but are studied piecewise and their…

Artificial Intelligence · Computer Science 2016-08-22 Adrien Basso-Blandin , Walter Fontana , Russ Harmer

Recent advancements in image classification have demonstrated that contrastive learning (CL) can aid in further learning tasks by acquiring good feature representation from a limited number of data samples. In this paper, we applied CL to…

Machine Learning · Computer Science 2024-10-22 Anchen Sun , Elizabeth J. Franzmann , Zhibin Chen , Xiaodong Cai

In the medical domain, the continuous stream of scientific research contains contradictory results supported by arguments and counter-arguments. As medical expertise occurs at different levels, part of the human agents have difficulties to…

Artificial Intelligence · Computer Science 2016-07-28 Adrian Groza , Oana Popa

Recently, there has been an increase in the number of knowledge graphs that can be only queried by experts. However, describing questions using structured queries is not straightforward for non-expert users who need to have sufficient…

Computation and Language · Computer Science 2021-05-04 Abdelghny Orogat , Isabelle Liu , Ahmed El-Roby

Pre-trained language models (PLMs) have proven to be effective for document re-ranking task. However, they lack the ability to fully interpret the semantics of biomedical and health-care queries and often rely on simplistic patterns for…

Computation and Language · Computer Science 2023-05-09 Deepak Gupta , Dina Demner-Fushman

Cancer claims millions of lives yearly worldwide. While many therapies have been made available in recent years, by in large cancer remains unsolved. Exploiting computational predictive models to study and treat cancer holds great promise…

Quantitative Methods · Quantitative Biology 2022-11-22 Alexander Partin , Thomas S. Brettin , Yitan Zhu , Oleksandr Narykov , Austin Clyde , Jamie Overbeek , Rick L. Stevens

According to the World Health Organization (WHO), cancer is the second leading cause of death globally. Scientific research on different types of cancers grows at an ever-increasing rate, publishing large volumes of research articles every…

Computation and Language · Computer Science 2023-06-27 G. Jeyakodi , Arkadeep Pal , Debapratim Gupta , K. Sarukeswari , V. Amouda

Knowledge Components (KCs) linked to assessments enhance the measurement of student learning, enrich analytics, and facilitate adaptivity. However, generating and linking KCs to assessment items requires significant effort and…

Artificial Intelligence · Computer Science 2024-06-03 Steven Moore , Robin Schmucker , Tom Mitchell , John Stamper

Automating data extraction from clinical documents offers significant potential to improve efficiency in healthcare settings, yet deploying Natural Language Processing (NLP) solutions presents practical challenges. Drawing upon our…

Computation and Language · Computer Science 2025-08-18 Lovedeep Gondara , Gregory Arbour , Raymond Ng , Jonathan Simkin , Shebnum Devji

Computing many useful properties of Boolean formulas, such as their weighted or unweighted model count, is intractable on general representations. It can become tractable when formulas are expressed in a special form, such as the decision…

Logic in Computer Science · Computer Science 2025-01-23 Randal E. Bryant , Wojciech Nawrocki , Jeremy Avigad , Marijn J. H. Heule

Clinical tasks such as diagnosis and treatment require strong decision-making abilities, highlighting the importance of rigorous evaluation benchmarks to assess the reliability of large language models (LLMs). In this work, we introduce a…

Computation and Language · Computer Science 2025-07-04 Running Yang , Wenlong Deng , Minghui Chen , Yuyin Zhou , Xiaoxiao Li

Concept Bottleneck Models (CBMs) provide inherent interpretability by first mapping input samples to high-level semantic concepts, followed by a combination of these concepts for the final classification. However, the annotation of…

Machine Learning · Computer Science 2026-03-02 Yangyi Li , Mengdi Huai

One of the important issues in oncology is finding the genes that perturbation the cell functionality, and result in cancer propagation. The genes, namely driver genes, when they mutate in expression, result in cancer through activation of…

Molecular Networks · Quantitative Biology 2020-12-16 Mostafa Akhavansafar , Babak Teimourpour

Liver cancer has a high incidence rate, but primary healthcare settings often lack experienced doctors. Advances in large models and AI technologies offer potential assistance. This work aims to address limitations in liver cancer diagnosis…

Medical Physics · Physics 2024-06-27 Xuzhou Wu , Guangxin Li , Xing Wang , Zeyu Xu , Yingni Wang , Jianming Xian , Xueyu Wang , Gong Li , Kehong Yuan
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