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Accurate ECG interpretation is vital, yet complex cardiac data and "black-box" AI models limit clinical utility. Inspired by Transformer architectures' success in NLP for understanding sequential data, we frame ECG as the heart's unique…

Signal Processing · Electrical Eng. & Systems 2025-06-09 Berat Kutay Uğraş , Ömer Nezih Gerek , İbrahim Talha Saygı

Remote patient monitoring based on wearable single-lead electrocardiogram (ECG) devices has significant potential for enabling the early detection of heart disease, especially in combination with artificial intelligence (AI) approaches for…

Signal Processing · Electrical Eng. & Systems 2024-04-30 Aruna Mohan , Danne Elbers , Or Zilbershot , Fatemeh Afghah , David Vorchheimer

Real-world processes often generate data that are a mix of categorical and numeric values that are recorded at irregular and informative intervals. Discrete token-based approaches are limited in numeric representation capacity while methods…

Machine Learning · Computer Science 2025-06-02 Andrew J. Loza , Jun Yup Kim , Shangzheng Song , Yihang Liu , Joseph J. Y. Sung , R Andrew Taylor , Dennis L. Shung

The emergence of deep learning has significantly enhanced the analysis of electrocardiograms (ECGs), a non-invasive method that is essential for assessing heart health. Despite the complexity of ECG interpretation, advanced deep learning…

Machine Learning · Computer Science 2023-06-05 Zibin Zhao

ECG heartbeat classification plays a vital role in diagnosis of cardiac arrhythmia. The goal of the Physionet/CinC 2021 challenge was to accurately classify clinical diagnosis based on 12, 6, 4, 3 or 2-lead ECG recordings in order to aid…

Modelling the complex spatiotemporal patterns of large-scale brain dynamics is crucial for neuroscience, but traditional methods fail to capture the rich structure in modalities such as magnetoencephalography (MEG). Recent advances in deep…

Machine Learning · Computer Science 2025-10-22 Rukuang Huang , Sungjun Cho , Chetan Gohil , Oiwi Parker Jones , Mark Woolrich

Transformer-based models have improved predictive modeling on longitudinal electronic health records through large-scale self-supervised pretraining. However, most EHR transformer architectures treat each clinical encounter as an unordered…

Machine Learning · Computer Science 2026-03-17 Krish Tadigotla

Wearable systems for the continuous and real-time monitoring of cardiovascular diseases are becoming widespread and valuable assets in diagnosis and therapy. A promising approach for real-time analysis of the electrocardiographic (ECG)…

Signal Processing · Electrical Eng. & Systems 2024-06-24 Paola Busia , Matteo Antonio Scrugli , Victor Jean-Baptiste Jung , Luca Benini , Paolo Meloni

Although we have witnessed great success of pre-trained models in natural language processing (NLP) and computer vision (CV), limited progress has been made for general time series analysis. Unlike NLP and CV where a unified model can be…

Machine Learning · Computer Science 2023-10-17 Tian Zhou , PeiSong Niu , Xue Wang , Liang Sun , Rong Jin

Cardiovascular disease remains one of the leading causes of mortality worldwide, underscoring the need for accurate as well as interpretable diagnostic machine learning tools. In this work, we investigate heart disease classification using…

Signal Processing · Electrical Eng. & Systems 2025-04-08 Mario Padilla Rodriguez , Mohamed Nafea

Large-scale pre-trained models (PTMs) such as BERT and GPT have recently achieved great success in Natural Language Processing and Computer Vision domains. However, the development of PTMs on healthcare time-series data is lagging…

Machine Learning · Computer Science 2024-09-10 Ziyang Song , Qincheng Lu , Hao Xu , He Zhu , David L. Buckeridge , Yue Li

Transformers are groundbreaking architectures that have changed a flow of deep learning, and many high-performance models are developing based on transformer architectures. Transformers implemented only with attention with encoder-decoder…

Human-Computer Interaction · Computer Science 2021-12-20 Young-Eun Lee , Seo-Hyun Lee

Interpreting and communicating electrocardiogram (ECG) findings are crucial yet challenging tasks in cardiovascular diagnosis, traditionally requiring significant expertise and precise clinical communication. This paper introduces…

Signal Processing · Electrical Eng. & Systems 2025-10-30 Koustav Mallick , Neel Singh , Mohammedreza Hajiarbabi

Many Transformer-based pre-trained models for code have been developed and applied to code-related tasks. In this paper, we review the existing literature, examine the suitability of model architectures for different tasks, and look at the…

Software Engineering · Computer Science 2023-10-03 Yan Xiao , Xinyue Zuo , Lei Xue , Kailong Wang , Jin Song Dong , Ivan Beschastnikh

Foundation models are large-scale machine learning models that are pre-trained on massive amounts of data and can be adapted for various downstream tasks. They have been extensively applied to tasks in Natural Language Processing and…

This study introduces a novel application of a Generative Pre-trained Transformer (GPT) model tailored for photoplethysmography (PPG) signals, serving as a foundation model for various downstream tasks. Adapting the standard GPT…

Machine Learning · Computer Science 2025-03-12 Zhaoliang Chen , Cheng Ding , Saurabh Kataria , Runze Yan , Minxiao Wang , Randall Lee , Xiao Hu

Electrocardiography (ECG), an electrical measurement which captures cardiac activities, is the gold standard for diagnosing cardiovascular disease (CVD). However, ECG is infeasible for continuous cardiac monitoring due to its requirement…

Signal Processing · Electrical Eng. & Systems 2022-12-06 Ella Lan

Accurate analysis of medical time series (MedTS) data, such as electroencephalography (EEG) and electrocardiography (ECG), plays a pivotal role in healthcare applications, including the diagnosis of brain and heart diseases. MedTS data…

Machine Learning · Computer Science 2026-05-08 Guoqi Yu , Juncheng Wang , Chen Yang , Jing Qin , Angelica I. Aviles-Rivero , Shujun Wang

Learning time-series representations for discriminative tasks, such as classification and regression, has been a long-standing challenge in the healthcare domain. Current pre-training methods are limited in either unidirectional next-token…

Artificial Intelligence · Computer Science 2024-08-27 Ziyang Song , Qincheng Lu , He Zhu , David Buckeridge , Yue Li

Pre-trained large transformer models have achieved remarkable performance in the fields of natural language processing and computer vision. However, the limited availability of public electroencephalogram (EEG) data presents a unique…

Signal Processing · Electrical Eng. & Systems 2024-04-16 Bingxin Wang , Xiaowen Fu , Yuan Lan , Luchan Zhang , Wei Zheng , Yang Xiang
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