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Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

Recognizing spatial relations and reasoning about them is essential in multiple applications including navigation, direction giving and human-computer interaction in general. Spatial relations between objects can either be explicit --…

Computation and Language · Computer Science 2020-07-21 Soham Dan , Hangfeng He , Dan Roth

The tumor microenvironment (TME) significantly impacts cancer prognosis due to its immune composition. While therapies for altering the immune composition, including immunotherapies, have shown exciting results for treating hematological…

Quantitative Methods · Quantitative Biology 2023-10-17 Zitong Jerry Wang , Alexander M. Xu , Aman Bhargava , Matt W. Thomson

Image Processing, Optimization and Prediction of an Image play a key role in Computer Science. Image processing provides a way to analyze and identify an image .Many areas like medical image processing, Satellite images, natural images and…

Computer Vision and Pattern Recognition · Computer Science 2013-05-14 Shweta Jain , Urmila Shrawankar

Generative artificial intelligence (AI) is rapidly transforming medical imaging by enabling capabilities such as data synthesis, image enhancement, modality translation, and spatiotemporal modeling. This review presents a comprehensive and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Xuanru Zhou , Cheng Li , Shuqiang Wang , Ye Li , Tao Tan , Hairong Zheng , Shanshan Wang

This paper investigates the problem of adjusting for spatial effects in genomic prediction. Despite being seldomly considered in genomic prediction, spatial effects often affect phenotypic measurements of plants. We consider a Gaussian…

Applications · Statistics 2020-06-09 Xiaojun Mao , Somak Dutta , Raymond K. W. Wong , Dan Nettleton

Spatial grounding, the process of associating natural language expressions with corresponding image regions, has rapidly advanced due to the introduction of transformer-based models, significantly enhancing multimodal representation and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Ijazul Haq , Muhammad Saqib , Yingjie Zhang

A recent technology breakthrough in spatial molecular profiling has enabled the comprehensive molecular characterizations of single cells while preserving spatial information. It provides new opportunities to delineate how cells from…

Applications · Statistics 2021-10-07 Xi Jiang , Qiwei Li , Guanghua Xiao

The field of mathematical morphology offers well-studied techniques for image processing. In this work, we view morphological operations through the lens of persistent homology, a tool at the heart of the field of topological data analysis.…

Computational Geometry · Computer Science 2021-03-25 Yu-Min Chung , Sarah Day , Chuan-Shen Hu

Many works in the recent literature introduce semantic mapping methods that use CNNs (Convolutional Neural Networks) to recognize semantic properties in images. The types of properties (eg.: room size, place category, and objects) and their…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Ygor C. N. Sousa , Hansenclever F. Bassani

Biological intelligence is remarkable in its ability to produce complex behaviour in many diverse situations through data efficient, generalisable and transferable skill acquisition. It is believed that learning "good" sensory…

Neurons and Cognition · Quantitative Biology 2022-03-18 Irina Higgins , Sébastien Racanière , Danilo Rezende

Spatial transcriptomics (ST) provides essential spatial context by mapping gene expression within tissue, enabling detailed study of cellular heterogeneity and tissue organization. However, aligning ST data with histology images poses…

Building Information Modeling (BIM) has revolutionized the construction industry by providing a comprehensive digital representation of building structures throughout their lifecycle. However, existing research lacks effective methods for…

Computational Engineering, Finance, and Science · Computer Science 2025-10-28 Jin Han , Xin-Zheng Lu , Jia-Rui Lin

This article proposes a generic framework to process jointly the spatial and spectral information of hyperspectral images. First, sub-images are extracted. Then each of these sub-images follows two parallel workflows, one dedicated to the…

Deep learning based localization and mapping has recently attracted significant attention. Instead of creating hand-designed algorithms through exploitation of physical models or geometric theories, deep learning based solutions provide an…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Changhao Chen , Bing Wang , Chris Xiaoxuan Lu , Niki Trigoni , Andrew Markham

Intelligent embodied agents (e.g. robots) need to perform complex semantic tasks in unfamiliar environments. Among many skills that the agents need to possess, building and maintaining a semantic map of the environment is most crucial in…

Robotics · Computer Science 2025-08-13 Sonia Raychaudhuri , Angel X. Chang

Spatial transcriptomics (ST) enables the visualization of gene expression within the context of tissue morphology. This emerging discipline has the potential to serve as a foundation for developing tools to design precision medicines.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Shivam Kumar , Samrat Chatterjee

Spatial transcriptomics (ST) bridges gene expression and tissue morphology but faces clinical adoption barriers due to technical complexity and prohibitive costs. While computational methods predict gene expression from H&E-stained…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Ziqiao Weng , Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee AD Cooper , Weidong Cai , Bo Zhou

Although 3D shape matching and interpolation are highly interrelated, they are often studied separately and applied sequentially to relate different 3D shapes, thus resulting in sub-optimal performance. In this work we present a unified…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Dongliang Cao , Marvin Eisenberger , Nafie El Amrani , Daniel Cremers , Florian Bernard

Recent years have witnessed remarkable progress in multimodal learning within computational pathology. Existing models primarily rely on vision and language modalities; however, language alone lacks molecular specificity and offers limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Minghao Han , Dingkang Yang , Linhao Qu , Zizhi Chen , Gang Li , Han Wang , Jiacong Wang , Lihua Zhang