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Recent studies have demonstrated promising performance of ChatGPT and GPT-4 on several medical domain tasks. However, none have assessed its performance using a large-scale real-world electronic health record database, nor have evaluated…

Computation and Language · Computer Science 2023-07-18 Jingqing Zhang , Kai Sun , Akshay Jagadeesh , Mahta Ghahfarokhi , Deepa Gupta , Ashok Gupta , Vibhor Gupta , Yike Guo

The integration of Large Language Models (LLMs) into the healthcare domain has the potential to significantly enhance patient care and support through the development of empathetic, patient-facing chatbots. This study investigates an…

Computation and Language · Computer Science 2024-05-28 Man Luo , Christopher J. Warren , Lu Cheng , Haidar M. Abdul-Muhsin , Imon Banerjee

The proliferation of Large Language Models (LLMs) and Intelligent Virtual Agents acting as psychotherapists presents significant opportunities for expanding mental healthcare access. However, their deployment has also been linked to serious…

Computation and Language · Computer Science 2025-09-23 Ian Steenstra , Timothy W. Bickmore

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

Artificial Intelligence · Computer Science 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

Large language models (LLMs) are increasingly used for diagnostic tasks in medicine. In clinical practice, the correct diagnosis can rarely be immediately inferred from the initial patient presentation alone. Rather, reaching a diagnosis…

Artificial Intelligence · Computer Science 2026-02-20 Hui Min Wong , Philip Heesen , Pascal Janetzky , Martin Bendszus , Stefan Feuerriegel

Therapeutic art activities, such as expressive drawing and painting, require the synergy between creative visual production and interactive dialogue. Recent advancements in Multimodal Large Language Models (MLLMs) have expanded the capacity…

Human-Computer Interaction · Computer Science 2026-05-12 Le Lin , Zihao Zhu , Rainbow Tin Hung Ho , Jing Liao , Yuhan Luo

Accurate diagnosis of Mendelian diseases is crucial for precision therapy and assistance in preimplantation genetic diagnosis. However, existing methods often fall short of clinical standards or depend on extensive datasets to build…

The advent of ChatGPT and similar large language models (LLMs) has revolutionized the human-AI interaction and information-seeking process. Leveraging LLMs as an alternative to search engines, users can now access summarized information…

Human-Computer Interaction · Computer Science 2024-04-18 Ben Wang

Medical question answer (QA) assistants respond to lay users' health-related queries by synthesizing information from multiple sources using natural language processing and related techniques. They can serve as vital tools to alleviate…

Computation and Language · Computer Science 2024-10-01 Prakash Chandra Sukhwal , Vaibhav Rajan , Atreyi Kankanhalli

Worldwide, several cases go undiagnosed due to poor healthcare support in remote areas. In this context, a centralized system is needed for effective monitoring and analysis of the medical records. A web-based patient diagnostic system is a…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Harish Rajora , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal

This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…

Artificial Intelligence · Computer Science 2024-04-11 Elham Nasarian , Roohallah Alizadehsani , U. Rajendra Acharya , Kwok-Leung Tsui

Systems engineering (SE) is evolving with the availability of generative artificial intelligence (AI) and the demand for a systems-of-systems perspective, formalized under the purview of mission engineering (ME) in the US Department of…

Software Engineering · Computer Science 2025-02-07 Max Ofsa , Taylan G. Topcu

Artificial intelligence (AI) is widely deployed to solve problems related to marketing attribution and budget optimization. However, AI models can be quite complex, and it can be difficult to understand model workings and insights without…

Computation and Language · Computer Science 2024-04-23 Yilin Gao , Sai Kumar Arava , Yancheng Li , James W. Snyder

Generative Large Language Models (gLLMs), such as ChatGPT, are increasingly being used in communication research for content analysis. Studies show that gLLMs can outperform both crowd workers and trained coders, such as research…

Artificial Intelligence · Computer Science 2025-10-29 Daria Kravets-Meinke , Hannah Schmid-Petri , Sonja Niemann , Ute Schmid

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

This review introduces the transformative potential of generative Artificial Intelligence (AI) and foundation models, including large language models (LLMs), for health technology assessment (HTA). We explore their applications in four…

Machine Learning · Computer Science 2024-09-24 Rachael Fleurence , Jiang Bian , Xiaoyan Wang , Hua Xu , Dalia Dawoud , Mitch Higashi , Jagpreet Chhatwal

Artificial Intelligence (AI) for supporting healthcare services has never been more necessitated than by the recent global pandemic. Here, we review the state-of-the-art in AI-enabled Chatbots in healthcare proposed during the last 10 years…

Artificial Intelligence · Computer Science 2023-08-09 Basabdatta Sen Bhattacharya , Vibhav Sinai Pissurlenkar

With the boom of e-commerce and web applications, recommender systems have become an important part of our daily lives, providing personalized recommendations based on the user's preferences. Although deep neural networks (DNNs) have made…

Artificial Intelligence · Computer Science 2024-03-13 Xiaonan Xu , Yichao Wu , Penghao Liang , Yuhang He , Han Wang

Machine learning (ML) is crucial in network anomaly detection for proactive threat hunting, reducing detection and response times significantly. However, challenges in model training, maintenance, and frequent false positives impact its…

Cryptography and Security · Computer Science 2023-09-29 Tarek Ali , Panos Kostakos

Demand for mental health support through AI chatbots is surging, though current systems present several limitations, like sycophancy or overvalidation, and reinforcement of maladaptive beliefs. A core obstacle to the creation of better…

Computation and Language · Computer Science 2025-12-08 José Pombal , Maya D'Eon , Nuno M. Guerreiro , Pedro Henrique Martins , António Farinhas , Ricardo Rei