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In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

Volunteer computing is being used successfully for large scale scientific computations. This research is in the context of Volpex, a programming framework that supports communicating parallel processes in a volunteer environment. Redundancy…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-03-14 Mohammad Tanvir Rahman , Hien Nguyen , Jaspal Subhlok , Gopal Pandurangan

Scaling up model and data size have demonstrated impressive performance improvement over a wide range of tasks. Despite extensive studies on scaling behaviors for general-purpose tasks, medical images exhibit substantial differences from…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Jiarun Liu , Hong-Yu Zhou , Weijian Huang , Hao Yang , Dongning Song , Tao Tan , Yong Liang , Shanshan Wang

Since the release of GPT2-1.5B in 2019, the large language models (LLMs) have evolved from specialized deep models to versatile foundation models. While demonstrating remarkable zero-shot ability, the LLMs still require fine-tuning on local…

Artificial Intelligence · Computer Science 2025-08-07 Yanjie Dong , Haijun Zhang , Chengming Li , Song Guo , Victor C. M. Leung , Xiping Hu

Efficient and robust bioprocess control is essential for maximizing performance and adaptability in advanced biotechnological systems. In this work, we present a reinforcement-learning framework for multi-setpoint and multi-trajectory…

Systems and Control · Electrical Eng. & Systems 2025-07-29 Sebastián Espinel-Ríos , José L. Avalos , Ehecatl Antonio del Rio Chanona , Dongda Zhang

Large Language Models (LLMs) are rapidly becoming critical infrastructure for enterprise applications, driving unprecedented demand for GPU-based inference services. A key operational challenge arises from the two-phase nature of LLM…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-04 Ruihan Lin , Zezhen Ding , Zean Han , Jiheng Zhang

We tackle the challenge of feature embedding for the purposes of improving the click-through rate prediction process. We select three models: logistic regression, factorization machines and deep factorization machines, as our baselines and…

Machine Learning · Computer Science 2022-09-21 Samo Pahor , Davorin Kopič , Jure Demšar

Large language models (LLMs) have made a profound impact across various fields due to their advanced capabilities. However, training these models at unprecedented scales requires extensive AI accelerator clusters and sophisticated…

Video Large Language Models (Video-LLMs) require continual learning to adapt to non-stationary real-world data. However, existing benchmarks fall short of evaluating modern foundation models: many still rely on models without large-scale…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Haiyang Guo , Yichen Shi , Fei Zhu , Wenzhuo Liu , Hongbo Zhao , Fanhu Zeng , Shijie Ma , Da-Han Wang , Xu-Yao Zhang

Speculative decoding accelerates memory-bound LLM inference without quality degradation by using a fast drafter to propose multiple candidate tokens and the target model to verify them in parallel. However, conventional sequential…

Computation and Language · Computer Science 2026-05-20 Yaojie Zhang , Jianuo Huang , Junlong Ke , Yuhang Han , Yongji Long , Tianchen Zhao , Biqing Qi , Linfeng Zhang

The pretrained large language models (LLMs) are finetuned with labeled data for better instruction following ability and alignment with human values. In this paper, we study the learning dynamics of LLM finetuning on reasoning tasks and…

Computation and Language · Computer Science 2025-09-30 Zhiwen Ruan , Yun Chen , Yutao Hou , Peng Li , Yang Liu , Guanhua Chen

The paradigm of scaling Large Language Models (LLMs) in both parameter size and test time has pushed the boundaries of AI capabilities, but at the cost of making the traditional generative evaluation paradigm prohibitively expensive,…

Machine Learning · Computer Science 2026-04-02 Zhichen Liu , Tianle Lun , Zhibin Wen , Hao An , Yulin Ou , Jianhui Xu , Hao Zhang , Wenyi Fang , Yang Zheng , Yang Xu

A vast amount of instruction tuning data is crucial for the impressive performance of Large Multimodal Models (LMMs), but the associated computational costs and data collection demands during supervised fine-tuning make it impractical for…

Machine Learning · Computer Science 2025-07-22 Haiyang Guo , Fanhu Zeng , Fei Zhu , Wenzhuo Liu , Da-Han Wang , Jian Xu , Xu-Yao Zhang , Cheng-Lin Liu

Supervised fine-tuning (SFT) is a pivotal approach to adapting large language models (LLMs) for downstream tasks; however, performance often suffers from the ``seesaw phenomenon'', where indiscriminate parameter updates yield progress on…

Computation and Language · Computer Science 2025-09-22 Yao Wang , Di Liang , Minlong Peng

Large language models for code are advancing fast, yet our ability to evaluate them lags behind. Current benchmarks focus on narrow tasks and single metrics, which hide critical gaps in robustness, interpretability, fairness, efficiency,…

Supervised fine-tuning (SFT) plays a critical role for pretrained large language models (LLMs), notably enhancing their capacity to acquire domain-specific knowledge while preserving or potentially augmenting their general-purpose…

Machine Learning · Computer Science 2026-03-31 Ali Taheri , Alireza Taban , Qizhou Wang , Shanshan Ye , Abdolreza Mirzaei , Tongliang Liu , Bo Han

We present the design, implementation and engineering experience in building and deploying MegaScale, a production system for training large language models (LLMs) at the scale of more than 10,000 GPUs. Training LLMs at this scale brings…

Despite their remarkable capabilities, Large Language Models (LLMs) struggle to effectively leverage historical interaction information in dynamic and complex environments. Memory systems enable LLMs to move beyond stateless interactions by…

Computation and Language · Computer Science 2026-03-03 Jizhan Fang , Xinle Deng , Haoming Xu , Ziyan Jiang , Yuqi Tang , Ziwen Xu , Shumin Deng , Yunzhi Yao , Mengru Wang , Shuofei Qiao , Huajun Chen , Ningyu Zhang

Pre-training large language models on massive GPU clusters has made hardware faults routine rather than rare, driving the need for resilient training systems. Yet existing frameworks either focus on specific parallelism schemes or risk…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-25 Ziyue Liu , Zhengyang Wang , Ruijie Zhang , Avinash Maurya , Hui Zhou , Paul Hovland , Sheng Di , Franck Cappello , Bogdan Nicolae , Zheng Zhang

In scientific computing and data science disciplines, it is often necessary to share application workflows and repeat results. Current tools containerize application workflows, and share the resulting container for repeating results. These…

Databases · Computer Science 2022-02-18 Naga Nithin Manne , Shilvi Satpati , Tanu Malik , Amitabha Bagchi , Ashish Gehani , Amitabh Chaudhary