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Related papers: Quantum Long Short-Term Memory for Drug Discovery

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Machine learning applications are limited by computational power. In this paper, we gain novel insights into the application of quantum annealing (QA) to machine learning (ML) through experiments in natural language processing (NLP),…

Quantum Physics · Physics 2016-03-28 Joseph Dulny , Michael Kim

Quantum computing holds promise for revolutionizing computational chemistry simulations, particularly in drug discovery. However, current quantum hardware is limited by noise and scale, necessitating bridging technologies. This study…

Quantum Physics · Physics 2025-04-16 Marek Kowalik , Ellen Michael , Peter Pogány , Phalgun Lolur

Despite significant efforts, the realization of the hybrid quantum-classical algorithms has predominantly been confined to proof-of-principles, mainly due to the hardware noise. With fault-tolerant implementation being a long-term goal,…

Quantum Physics · Physics 2025-04-10 Srushti Patil , Dibyendu Mondal , Rahul Maitra

Reconstructing quantum states from measurement data represents a formidable challenge in quantum information science, especially as system sizes grow beyond the reach of traditional tomography methods. While recent studies have explored…

Quantum Physics · Physics 2026-04-06 Shabnam Jabeen , Dmytro Kurdydyk , Aadi Palnitkar , Mihir Talati , Jeffrey Yan , Jinghong Yang

As medium-scale quantum computers progress, the application of quantum algorithms across diverse fields like simulating physical systems, chemistry, optimization, and cryptography becomes more prevalent. However, these quantum computers,…

Quantum Physics · Physics 2024-04-04 Purnachandra Mandadapu

Hybrid Quantum-Classical (HQC) Architectures are used in near-term NISQ Quantum Computers for solving Quantum Machine Learning problems. The quantum advantage comes into picture due to the exponential speedup offered over classical…

Quantum Physics · Physics 2024-04-16 Syed Farhan Ahmad , Raghav Rawat , Minal Moharir

Integrating quantum mechanics into drug discovery marks a decisive shift from empirical trial-and-error toward quantitative precision. However, the prohibitive cost of ab initio molecular dynamics has historically forced a compromise…

Quantum sources with strong correlations are essential but delicate resources in quantum information science and engineering. Decoherence and loss are the primary factors that degrade nonclassical quantum correlations, with scattering…

Quantum Physics · Physics 2025-03-31 Edward W. Steele , Donald R. Reising , Tian Li

Quantum machine learning (QML) networks promise to have some computational (or quantum) advantage for classifying supervised datasets (e.g., satellite images) over some conventional deep learning (DL) techniques due to their expressive…

Quantum Physics · Physics 2023-09-21 Soronzonbold Otgonbaatar , Gottfried Schwarz , Mihai Datcu , Dieter Kranzlmüller

The emergence of quantum computing and related technologies presents opportunities for enhancing network security. The transition towards quantum computational power paves the way for creating strategies to mitigate the constantly advancing…

Cryptography and Security · Computer Science 2024-11-08 Diego Abreu , Christian Esteve Rothenberg , Antonio Abelem

Learning problems involving quantum data are natural candidates for demonstrating an advantage in quantum machine learning. Recent results indicate that, for certain tasks and under noiseless conditions, coherent processing of quantum data…

Recently deep learning based quantitative structure-activity relationship (QSAR) models has shown surpassing performance than traditional methods for property prediction tasks in drug discovery. However, most DL based QSAR models are…

Biomolecules · Quantitative Biology 2023-04-25 Zhifeng Gao , Xiaohong Ji , Guojiang Zhao , Hongshuai Wang , Hang Zheng , Guolin Ke , Linfeng Zhang

Quantum machine learning (QML) has attracted considerable research interest, yet whether it offers practical benefits over classical approaches remains an open question. The choice of data encoding significantly influences QML performance,…

Quantum Physics · Physics 2026-05-19 Lena Tokuhiro , Amine Bentellis , Jeanette Miriam Lorenz

We investigate whether a novel method of quantum machine learning (QML) can identify anomalous events in X-ray light curves as transient events and apply it to detect such events from the XMM-Newton 4XMM-DR14 catalog. The architecture we…

High Energy Astrophysical Phenomena · Physics 2025-07-14 Taiki Kawamuro , Shinya Yamada , Shigehiro Nagataki , Shunji Matsuura , Yusuke Sakai , Satoshi Yamada

This study explores the application and performance of Transformational Machine Learning (TML) in drug discovery. TML, a meta learning algorithm, excels in exploiting common attributes across various domains, thus developing composite…

Biomolecules · Quantitative Biology 2023-10-02 Adnan Mahmud , Oghenejokpeme Orhobor , Ross D. King

Exploiting the fact that samples drawn from a quantum annealer inherently follow a Boltzmann-like distribution, annealing-based Quantum Boltzmann Machines (QBMs) have gained increasing popularity in the quantum research community. While…

Hybrid Quantum-Classical Machine Learning (ML) is an emerging field, amalgamating the strengths of both classical neural networks and quantum variational circuits on the current noisy intermediate-scale quantum devices. This paper performs…

Accurate amine property prediction is essential for optimizing CO2 capture efficiency in post-combustion processes. Quantum machine learning (QML) can enhance predictive modeling by leveraging superposition, entanglement, and interference…

Quantum Physics · Physics 2025-06-24 Hyein Cho , Jeonghoon Kim , Hocheol Lim

Artificial Intelligence (AI) systems have shown good success at classifying. However, the lack of explainability is a true and significant challenge, especially in high-stakes domains, such as health and finance, where understanding is…

Machine Learning · Computer Science 2026-01-14 A. M. A. S. D. Alagiyawanna , Asoka Karunananda , Thushari Silva , A. Mahasinghe

One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo