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We present a divide-and-conquer version of the Cylindrical Algebraic Decomposition (CAD) algorithm. The algorithm represents the input as a Boolean combination of subformulas, computes cylindrical algebraic decompositions of solution sets…

Symbolic Computation · Computer Science 2014-02-05 Adam Strzebonski

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

Several quantum algorithms for linear algebra problems, and in particular quantum machine learning problems, have been "dequantized" in the past few years. These dequantization results typically hold when classical algorithms can access the…

Quantum Physics · Physics 2024-12-16 François Le Gall

Rational design of compounds with specific properties requires conceptual understanding and fast evaluation of molecular properties throughout chemical compound space (CCS) -- the huge set of all potentially stable molecules. Recent…

Chemical Physics · Physics 2019-12-02 O. Anatole von Lilienfeld , Klaus-Robert Müller , Alexandre Tkatchenko

Recent developments in higher order calculations within the framework of Dimensional Reduction, the preferred regularization scheme for supersymmetric theories, are reported on. Special emphasis is put on the treatment of evanescent…

High Energy Physics - Phenomenology · Physics 2007-06-21 Robert Harlander , Philipp Kant , Luminita Mihaila , Matthias Steinhauser

This article provides an introduction to and review of the field of computer-aided molecular design (CAMD). It is intended to be approachable for the absolute beginner as well as useful to the seasoned CAMD practitioner. We begin by…

Computational Engineering, Finance, and Science · Computer Science 2017-01-17 Nick D. Austin , Nikolaos V. Sahinidis , Daniel W. Trahan

Modern adiabatic quantum computers (AQC) are already used to solve difficult combinatorial optimisation problems in various domains of science. Currently, only a few applications of AQC in computer vision have been demonstrated. We review…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Vladislav Golyanik , Christian Theobalt

A Cylindrical Algebraic Decomposition (CAD) is a decomposition of R^n into a finite collection of semialgebraic cells. A CAD satisfies the "frontier condition" if, for every cell C, there is a collection of cells of the decomposition whose…

Algebraic Geometry · Mathematics 2023-07-18 Hollie Baker

Arrays of quantum dots (QDs) are a promising candidate system to realize scalable, coupled qubit systems and serve as a fundamental building block for quantum computers. In such semiconductor quantum systems, devices now have tens of…

Quantum Physics · Physics 2023-05-26 Justyna P. Zwolak , Jacob M. Taylor

Advances in the field of Machine Learning and Deep Neural Networks (DNNs) has enabled rapid development of sophisticated and autonomous systems. However, the inherent complexity to rigorously assure the safe operation of such systems…

Machine Learning · Computer Science 2019-09-23 Hao Ren , Sai Krishnan Chandrasekar , Anitha Murugesan

Typically, a practical algorithm of hardware verification obtains a semantic result by being applied to a particular formula $F$. That is, although this algorithm uses the specifics of $F$ (sometimes inadvertently), its result holds for all…

Logic in Computer Science · Computer Science 2026-05-13 Eugene Goldberg

The use of geometric and symmetry techniques in quantum and classical information processing has a long tradition across the physical sciences as a means of theoretical discovery and applied problem solving. In the modern era, the emergent…

Quantum Physics · Physics 2024-09-10 Elija Perrier

Recent advancements in quantum computing (QC) and machine learning (ML) have fueled significant research efforts aimed at integrating these two transformative technologies. Quantum machine learning (QML), an emerging interdisciplinary…

Quantum Physics · Physics 2025-04-24 Samuel Yen-Chi Chen , Zhiding Liang

The cylindrical algebraic covering method was originally proposed to decide the satisfiability of a set of non-linear real arithmetic constraints. We reformulate and extend the cylindrical algebraic covering method to allow for checking the…

Symbolic Computation · Computer Science 2025-10-07 Jasper Nalbach , Gereon Kremer

Modern software systems complexity challenges efficient testing, as traditional machine learning (ML) struggles with large test suites. This research presents a hybrid framework integrating Quantum Annealing with ML to optimize test case…

Software Engineering · Computer Science 2025-06-04 Gopichand Bandarupalli

We survey both old and new developments in the theory of algorithms in real algebraic geometry -- starting from effective quantifier elimination in the first order theory of reals due to Tarski and Seidenberg, to more recent algorithms for…

Algebraic Geometry · Mathematics 2014-09-05 Saugata Basu

When building a cylindrical algebraic decomposition (CAD) savings can be made in the presence of an equational constraint (EC): an equation logically implied by a formula. The present paper is concerned with how to use multiple ECs,…

Symbolic Computation · Computer Science 2015-07-20 Matthew England , Russell Bradford , James H. Davenport

Earlier, we introduced Partial Quantifier Elimination (PQE). It is a $\mathit{generalization}$ of regular quantifier elimination where one can take a $\mathit{part}$ of the formula out of the scope of quantifiers. We apply PQE to CNF…

Logic in Computer Science · Computer Science 2024-07-16 Eugene Goldberg

We investigate the distribution of cells by dimension in cylindrical algebraic decompositions (CADs). We find that they follow a standard distribution which seems largely independent of the underlying problem or CAD algorithm used. Rather,…

Symbolic Computation · Computer Science 2015-02-13 David Wilson , Matthew England , Russell Bradford , James H. Davenport

Quantum computers show promise to solve select problems otherwise intractable on classical computers. However, noisy intermediate-scale quantum (NISQ) era devices are currently prone to various sources of error. Quantum error correction…

Quantum Physics · Physics 2026-02-25 Maxwell Poster , Sayam Sethi , Jonathan Baker