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The popularity of machine learning has increased the risk of unfair models getting deployed in high-stake applications, such as justice system, drug/vaccination design, and medical diagnosis. Although there are effective methods to train…

Machine Learning · Computer Science 2022-07-14 Mohit Bajaj , Lingyang Chu , Vittorio Romaniello , Gursimran Singh , Jian Pei , Zirui Zhou , Lanjun Wang , Yong Zhang

Vision-language foundation models (VLMs) have shown impressive performance in guiding image generation through text, with emerging applications in medical imaging. In this work, we are the first to investigate the question: 'Can fine-tuned…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Amar Kumar , Anita Kriz , Barak Pertzov , Tal Arbel

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Over the past decades, researchers and ML practitioners have come up with better and better ways to build, understand and improve the quality of ML models, but mostly under the key assumption that the training data is distributed…

Machine Learning · Computer Science 2019-10-14 Yeounoh Chung , Peter J. Haas , Eli Upfal , Tim Kraska

We study whether deep networks for medical imaging learn useful nonrobust features - predictive input patterns that are not human interpretable and highly susceptible to small adversarial perturbations - and how these features impact test…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Coenraad Mouton , Randle Rabe , Niklas C. Koser , Nicolai Krekiehn , Christopher Hansen , Jan-Bernd Hövener , Claus-C. Glüer

Deep learning methods have become very popular for the processing of natural images, and were then successfully adapted to the neuroimaging field. As these methods are non-transparent, interpretability methods are needed to validate them…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Elina Thibeau-Sutre , Sasha Collin , Ninon Burgos , Olivier Colliot

This paper claims that machine learning models deployed in high stakes domains such as medicine must be interpretable, shareable, reproducible and accountable. We argue that these principles should form the foundational design criteria for…

Machine Learning · Computer Science 2025-08-25 Ayyüce Begüm Bektaş , Mithat Gönen

The identification and quantification of markers in medical images is critical for diagnosis, prognosis, and disease management. Supervised machine learning enables the detection and exploitation of findings that are known a priori after…

Interpretability and small labelled datasets are key issues in the practical application of deep learning, particularly in areas such as medicine. In this paper, we present a semi-supervised technique that addresses both these issues by…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Jarrel Seah , Jennifer Tang , Andy Kitchen , Jonathan Seah

Image-to-image translation is an ill-posed problem as unique one-to-one mapping may not exist between the source and target images. Learning-based methods proposed in this context often evaluate the performance on test data that is similar…

Image and Video Processing · Electrical Eng. & Systems 2021-10-08 Uddeshya Upadhyay , Viswanath P. Sudarshan , Suyash P. Awate

A medical AI system's generalizability describes the continuity of its performance acquired from varying geographic, historical, and methodologic settings. Previous literature on this topic has mostly focused on "how" to achieve high…

Image and Video Processing · Electrical Eng. & Systems 2022-12-19 Engin Dikici , Xuan Nguyen , Noah Takacs , Luciano M. Prevedello

Computer vision leveraging deep learning has achieved significant success in the last decade. Despite the promising performance of the existing deep models in the recent literature, the extent of models' reliability remains unknown.…

Computer Vision and Pattern Recognition · Computer Science 2020-04-13 Seyed Omid Sajedi , Xiao Liang

Despite remarkable success in unpaired image-to-image translation, existing systems still require a large amount of labeled images. This is a bottleneck for their real-world applications; in practice, a model trained on labeled CelebA…

Computer Vision and Pattern Recognition · Computer Science 2019-12-09 Hyojin Bahng , Sunghyo Chung , Seungjoo Yoo , Jaegul Choo

Interpretability is often an essential requirement in medical imaging. Advanced deep learning methods are required to address this need for explainability and high performance. In this work, we investigate whether additional information…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Luisa Gallee , Meinrad Beer , Michael Goetz

Interpretability is a crucial factor in building reliable models for various medical applications. Concept Bottleneck Models (CBMs) enable interpretable image classification by utilizing human-understandable concepts as intermediate…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Injae Kim , Jongha Kim , Joonmyung Choi , Hyunwoo J. Kim

Medical image-language pre-training aims to align medical images with clinically relevant text to improve model performance on various downstream tasks. However, existing models often struggle with the variability and ambiguity inherent in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Shreyank N Gowda , Ruichi Zhang , Xiao Gu , Ying Weng , Lu Yang

The growing adoption of Graph Neural Networks (GNNs) in high-stakes domains like healthcare and finance demands reliable explanations of their decision-making processes. While inherently interpretable GNN architectures like Graph…

Machine Learning · Computer Science 2025-05-27 Rishabh Bhattacharya , Hari Shankar , Vaishnavi Shivkumar , Ponnurangam Kumaraguru

Driven by advancements in deep learning, computer-aided diagnoses have made remarkable progress. However, outside controlled laboratory settings, algorithms may encounter several challenges. In the medical domain, these difficulties often…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Arnav Aditya , Nitin Kumar , Saurabh Shigwan

Unsupervised neural machine translation (UNMT) has recently achieved remarkable results with only large monolingual corpora in each language. However, the uncertainty of associating target with source sentences makes UNMT theoretically an…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Yuanhang Su , Kai Fan , Nguyen Bach , C. -C. Jay Kuo , Fei Huang

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez