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Diffusion MRI tractography is an advanced imaging technique for quantitative mapping of the brain's structural connectivity. Whole brain tractography (WBT) data contains over hundreds of thousands of individual fiber streamlines (estimated…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Fan Zhang , Tengfei Xue , Weidong Cai , Yogesh Rathi , Carl-Fredrik Westin , Lauren J O'Donnell

Tracking microsctructural changes in the developing brain relies on accurate inter-subject image registration. However, most methods rely on either structural or diffusion data to learn the spatial correspondences between two or more…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Irina Grigorescu , Alena Uus , Daan Christiaens , Lucilio Cordero-Grande , Jana Hutter , A. David Edwards , Joseph V. Hajnal , Marc Modat , Maria Deprez

Diffusion magnetic resonance imaging (dMRI) and tractography provide means to study the anatomical structures within the white matter of the brain. When studying tractography data across subjects, it is usually necessary to align, i.e. to…

Machine Learning · Statistics 2016-02-01 Thien Bao Nguyen , Emanuele Olivetti , Paolo Avesani

Fine-grained radio map presents communication parameters of interest, e.g., received signal strength, at every point across a large geographical region. It can be leveraged to improve the efficiency of spectrum utilization for a large area,…

Signal Processing · Electrical Eng. & Systems 2025-07-09 Zhiyuan Liu , Shuhang Zhang , Qingyu Liu , Hongliang Zhang , Lingyang Song

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Accurate segmentation of punctate white matter lesions (PWMLs) are fundamental for the timely diagnosis and treatment of related developmental disorders. Automated PWMLs segmentation from infant brain MR images is challenging, considering…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Zehua Ren , Yongheng Sun , Miaomiao Wang , Yuying Feng , Xianjun Li , Chao Jin , Jian Yang , Chunfeng Lian , Fan Wang

Diffusion Weighted Imaging (DWI) is an advanced imaging technique commonly used in neuroscience and neurological clinical research through a Diffusion Tensor Imaging (DTI) model. Volumetric scalar metrics including fractional anisotropy,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Zihao Tang , Xinyi Wang , Lihaowen Zhu , Mariano Cabezas , Dongnan Liu , Michael Barnett , Weidong Cai , Chengyu Wang

We propose Microscopic Propagator Imaging (MPI) as a novel method to retrieve the indices of the microscopic propagator which is the probability density function of water displacements due to diffusion within the nervous tissue…

Neurons and Cognition · Quantitative Biology 2025-03-03 Tommaso Zajac , Gloria Menegaz , Marco Pizzolato

Accurate detection and segmentation of brain tumors from magnetic resonance imaging (MRI) are essential for diagnosis, treatment planning, and clinical monitoring. While convolutional architectures such as U-Net have long been the backbone…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Arman Behnam

Diffusion magnetic resonance imaging (MRI) has revealed important insights into white matter microstructure, but its application to gray matter remains comparatively less explored. Here, we investigate whether global patterns of gray-matter…

Quantitative Methods · Quantitative Biology 2026-04-13 Lucas Z. Brito , Ryan P. Cabeen , David H. Laidlaw

Score diffusion methods can learn probability densities from samples. The score of the noise-corrupted density is estimated using a deep neural network, which is then used to iteratively transport a Gaussian white noise density to a target…

Computer Vision and Pattern Recognition · Computer Science 2024-10-16 Zahra Kadkhodaie , Stéphane Mallat , Eero P. Simoncelli

Identification of tumor margins is essential for surgical decision-making for glioblastoma patients and provides reliable assistance for neurosurgeons. Despite improvements in deep learning architectures for tumor segmentation over the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Tianyi Ren , Abhishek Sharma , Juampablo Heras Rivera , Harshitha Rebala , Ethan Honey , Agamdeep Chopra , Jacob Ruzevick , Mehmet Kurt

Solving medical imaging data scarcity through semantic image generation has attracted growing attention in recent years. However, existing generative models mainly focus on synthesizing whole-organ or large-tissue structures, showing…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Jiahao Xia , Yutao Hu , Yaolei Qi , Zhenliang Li , Wenqi Shao , Junjun He , Ying Fu , Longjiang Zhang , Guanyu Yang

Image segmentation is crucial in many computational pathology pipelines, including accurate disease diagnosis, subtyping, outcome, and survivability prediction. The common approach for training a segmentation model relies on a pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Sachin Kumar Danisetty , Alexandros Graikos , Srikar Yellapragada , Dimitris Samaras

Accurate medical image segmentation is crucial for precise anatomical delineation. Deep learning models like U-Net have shown great success but depend heavily on large datasets and struggle with domain shifts, complex structures, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Hantao Zhang , Yuhe Liu , Jiancheng Yang , Weidong Guo , Xinyuan Wang , Pascal Fua

This study introduces a novel point-wise diffusion model that processes spatio-temporal points independently to efficiently predict complex physical systems with shape variations. This methodological contribution lies in applying forward…

Computational Physics · Physics 2025-08-05 Jiyong Kim , Sunwoong Yang , Namwoo Kang

The brain's white matter (WM) undergoes developmental and degenerative processes during the human lifespan. To investigate the relationship between WM anatomical regions and age, we study diffusion magnetic resonance imaging tractography…

Neurons and Cognition · Quantitative Biology 2023-07-06 Yuxiang Wei , Tengfei Xue , Yogesh Rathi , Nikos Makris , Fan Zhang , Lauren J. O'Donnell

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Diffusion models are powerful tools for sampling from high-dimensional distributions by progressively transforming pure noise into structured data through a denoising process. When equipped with a guidance mechanism, these models can also…

Machine Learning · Computer Science 2026-05-04 Saeed Mohseni-Sehdeh , Walid Saad , Kei Sakaguchi , Tao Yu

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti