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Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Accurate segmentation of brain tumors is vital for diagnosis, surgical planning, and treatment monitoring. Deep learning has advanced on benchmarks, but two issues limit clinical use: no uncertainty estimates for errors and no segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Andrew Zhou

Accurate tumor staging in lung cancer is crucial for prognosis and treatment planning and is governed by explicit anatomical criteria under fixed guidelines. However, most existing deep learning approaches treat this spatially structured…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Saniah Kayenat Chowdhury , Rusab Sarmun , Muhammad E. H. Chowdhury , Sohaib Bassam Zoghoul , Israa Al-Hashimi , Adam Mushtak , Amith Khandakar

Brachytherapy involves bringing a radioactive source near tumor tissue using implanted needles. Image-guided brachytherapy planning requires amongst others, the reconstruction of the needles. Manually annotating these needles on patient…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Vangelis Kostoulas , Arthur Guijt , Ellen M. Kerkhof , Bradley R. Pieters , Peter A. N. Bosman , Tanja Alderliesten

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

Advances in computing technology have allowed researchers across many fields of endeavor to collect and maintain vast amounts of observational statistical data such as clinical data, biological patient data, data regarding access of web…

Computer Vision and Pattern Recognition · Computer Science 2014-01-24 Narkhede Sachin G , Vaishali Khairnar

Healthcare research and development face significant obstacles due to data scarcity and stringent privacy regulations, such as HIPAA and the GDPR, restricting access to essential real-world medical data. These limitations impede innovation,…

Machine Learning · Computer Science 2025-10-17 Md Ibrahim Shikder Mahin , Md Shamsul Arefin , Md Tanvir Hasan

Machine learning heavily relies on data, but real-world applications often encounter various data-related issues. These include data of poor quality, insufficient data points leading to under-fitting of machine learning models, and…

Machine Learning · Computer Science 2025-04-07 Yingzhou Lu , Lulu Chen , Yuanyuan Zhang , Minjie Shen , Huazheng Wang , Xiao Wang , Capucine van Rechem , Tianfan Fu , Wenqi Wei

Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Wessam M. Salama , Ahmed Shokry

Accurate tumor segmentation is crucial for cancer diagnosis and treatment. While foundation models have advanced general-purpose segmentation, existing methods still struggle with: (1) limited incorporation of medical priors, (2) imbalance…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Runqi Meng , Sifan Song , Pengfei Jin , Yujin Oh , Lin Teng , Yulin Wang , Yiqun Sun , Ling Chen , Xiang Li , Quanzheng Li , Ning Guo , Dinggang Shen

Pancreatic tumor segmentation in contrast-enhanced computed tomography (CT) is clinically important yet technically challenging: lesions are often small, heterogeneous, and easily confused with surrounding soft tissue, and models that…

Quantitative Methods · Quantitative Biology 2026-04-24 Sunny Joy Ma , Xiang Ma

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Accurately evaluating model performance is crucial for deploying machine learning systems in real-world applications. Traditional methods often require a sufficiently large labeled test set to ensure a reliable evaluation. However, in many…

Machine Learning · Computer Science 2025-11-04 Hai Hoang Thanh , Duy-Tung Nguyen , Hung The Tran , Khoat Than

Supervised deep learning methods for segmentation require large amounts of labelled training data, without which they are prone to overfitting, not generalizing well to unseen images. In practice, obtaining a large number of annotations…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Krishna Chaitanya , Neerav Karani , Christian Baumgartner , Olivio Donati , Anton Becker , Ender Konukoglu

Microplastic particle ingestion or inhalation by humans is a problem of growing concern. Unfortunately, current research methods that use machine learning to understand their potential harms are obstructed by a lack of available data. Deep…

Machine Learning · Computer Science 2024-05-02 Daniel Platnick , Sourena Khanzadeh , Alireza Sadeghian , Richard Anthony Valenzano

The realm of medical image diagnosis has advanced significantly with the integration of computer-aided diagnosis and surgical systems. However, challenges persist, particularly in achieving precise image segmentation. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Mutyyba Asghar , Ahmad Raza Shahid , Akhtar Jamil , Kiran Aftab , Syed Ather Enam

Computational pathology is part of precision oncology medicine. The integration of high-throughput data including genomics, transcriptomics, proteomics, metabolomics, pathomics, and radiomics into clinical practice improves cancer treatment…

Image and Video Processing · Electrical Eng. & Systems 2022-06-07 Liangrui Pan , Zhichao Feng , Shaoliang Peng

Pancreatic cancer carries a poor prognosis and relies on endoscopic ultrasound (EUS) for targeted biopsy and radiotherapy. However, the speckle noise, low contrast, and unintuitive appearance of EUS make segmentation of pancreatic tumors…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Pascal Spiegler , Taha Koleilat , Arash Harirpoush , Corey S. Miller , Hassan Rivaz , Marta Kersten-Oertel , Yiming Xiao