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Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou

Manual brain tumor segmentation from MRI scans is challenging due to tumor heterogeneity, scarcity of annotated data, and class imbalance in medical imaging datasets. Synthetic data generated by generative models has the potential to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Aditi Jahagirdar , Sameer Joshi

Early detection and localization of pancreatic cancer can increase the 5-year survival rate for patients from 8.5% to 20%. Artificial intelligence (AI) can potentially assist radiologists in detecting pancreatic tumors at an early stage.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Bowen Li , Yu-Cheng Chou , Shuwen Sun , Hualin Qiao , Alan Yuille , Zongwei Zhou

AI requires extensive datasets, while medical data is subject to high data protection. Anonymization is essential, but poses a challenge for some regions, such as the head, as identifying structures overlap with regions of clinical…

This study leverages synthetic data as a validation set to reduce overfitting and ease the selection of the best model in AI development. While synthetic data have been used for augmenting the training set, we find that synthetic data can…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Qixin Hu , Alan Yuille , Zongwei Zhou

Tumor synthesis enables the creation of artificial tumors in medical images, facilitating the training of AI models for tumor detection and segmentation. However, success in tumor synthesis hinges on creating visually realistic tumors that…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Qi Chen , Xiaoxi Chen , Haorui Song , Zhiwei Xiong , Alan Yuille , Chen Wei , Zongwei Zhou

Accurate delineation of pancreatic tumors is critical for diagnosis, treatment planning, and outcome assessment, yet automated segmentation remains challenging due to anatomical variability and limited dataset availability. In this study,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Keshav Jha , William Sharp , Dominic LaBella

Accurate lesion segmentation in whole-body PET/CT scans is crucial for cancer diagnosis and treatment planning, but limited datasets often hinder the performance of automated segmentation models. In this paper, we explore the potential of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Lap Yan Lennon Chan , Chenxin Li , Yixuan Yuan

Automated segmentation of Pancreatic Ductal Adenocarcinoma (PDAC) from MRI is critical for clinical workflows but is hindered by poor tumor-tissue contrast and a scarcity of annotated data. This paper details our submission to the PANTHER…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Omer Faruk Durugol , Maximilian Rokuss , Yannick Kirchhoff , Klaus H. Maier-Hein

Despite the advances in medicine, cancer has remained a formidable challenge. Particularly in the case of pancreatic tumors, characterized by their diversity and late diagnosis, early detection poses a significant challenge crucial for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Reza Babaei , Samuel Cheng , Theresa Thai , Shangqing Zhao

Deep learning-based medical image segmentation models, such as U-Net, rely on high-quality annotated datasets to achieve accurate predictions. However, the increasing use of generative models for synthetic data augmentation introduces…

Image and Video Processing · Electrical Eng. & Systems 2025-02-07 Tianhao Li , Tianyu Zeng , Yujia Zheng , Chulong Zhang , Jingyu Lu , Haotian Huang , Chuangxin Chu , Fang-Fang Yin , Zhenyu Yang

Deep generative models and synthetic medical data have shown significant promise in addressing key challenges in healthcare, such as privacy concerns, data bias, and the scarcity of realistic datasets. While research in this area has grown…

Machine Learning · Computer Science 2025-02-05 Krishan Agyakari Raja Babu , Supriti Mulay , Om Prabhu , Mohanasankar Sivaprakasam

AI-driven tumor analysis has garnered increasing attention in healthcare. However, its progress is significantly hindered by the lack of annotated tumor cases, which requires radiologists to invest a lot of effort in collecting and…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Linshan Wu , Jiaxin Zhuang , Xuefeng Ni , Hao Chen

We develop a novel strategy to generate synthetic tumors. Unlike existing works, the tumors generated by our strategy have two intriguing advantages: (1) realistic in shape and texture, which even medical professionals can confuse with real…

Image and Video Processing · Electrical Eng. & Systems 2022-10-27 Qixin Hu , Junfei Xiao , Yixiong Chen , Shuwen Sun , Jie-Neng Chen , Alan Yuille , Zongwei Zhou

Pancreatic cancer, characterized by its notable prevalence and mortality rates, demands accurate lesion delineation for effective diagnosis and therapeutic interventions. The generalizability of extant methods is frequently compromised due…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Jun Li , Yijue Zhang , Haibo Shi , Minhong Li , Qiwei Li , Xiaohua Qian

In medical image diagnosis, pathology image analysis using semantic segmentation becomes important for efficient screening as a field of digital pathology. The spatial augmentation is ordinary used for semantic segmentation. Tumor images…

Machine Learning · Computer Science 2021-03-04 Takato Yasuno

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Tumor is a leading cause of death worldwide, with an estimated 10 million deaths attributed to tumor-related diseases every year. AI-driven tumor recognition unlocks new possibilities for more precise and intelligent tumor screening and…

This paper presents the winning solution of task 1 and the third-placed solution of task 3 of the BraTS challenge. The use of automated tools in clinical practice has increased due to the development of more and more sophisticated and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 André Ferreira , Tiago Jesus , Behrus Puladi , Jens Kleesiek , Victor Alves , Jan Egger

Pancreatic cancer with more than 60,000 new cases each year has less than 10 percent 5-year overall survival. Radiation therapy (RT) is an effective treatment for Locally advanced pancreatic cancer (LAPC). The current clinical RT workflow…

Medical Physics · Physics 2023-06-07 Hamed Hooshangnejad , Quan Chen , Xue Feng , Rui Zhang , Kai Ding
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