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Related papers: Milli-spinner thrombectomy

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Blood clots, consisting of red blood cells (RBCs) entrapped within a fibrin network, can cause life-threatening conditions such as stroke and heart attack. The recently developed milli-spinner thrombectomy device presents a promising…

Biological Physics · Physics 2025-05-09 Yilong Changa , Guansheng Li , Jay Sim , George Em Karniadakis , Ruike Renee Zhao

Vascular diseases such as atherosclerosis, thrombosis, and aneurysms can lead to life-threatening medical events. Conventional catheter- or guidewire-based interventional devices often struggle to navigate through highly tortuous…

Medical Physics · Physics 2026-04-06 Lu Lu , Luca Higgins , Jack Bernardo , Ruike Renee Zhao

Vascular diseases such as thrombosis, atherosclerosis, and aneurysm, which can lead to blockage of blood flow or blood vessel rupture, are common and life-threatening. Conventional minimally invasive treatments utilize catheters, or long…

Robotics · Computer Science 2024-10-29 Shuai Wu , Sophie Leanza , Lu Lu , Yilong Chang , Qi Li , Diego Stone , Ruike Renee Zhao

Minimally invasive interventions performed inside brain vessels with the synergistic use of microcatheters pushed over guidewires have revolutionized the way aneurysms, stroke, arteriovenous malformations, brain tumors and other…

Thrombolytic occlusions in stroke, pulmonary embolism and the peripheral vasculature are increasingly treated with aspiration, a catheter-based approach that employs suction to extract clots through a hollow catheter lumen. Unfortunately,…

Medical Physics · Physics 2024-05-21 Li Gong , Alex R. Wright , Kullervo Hynynen , David E. Goertz

Background: Mechanical Thrombectomy (MT) is a widely accepted first-line treatment for Acute Ischemic Stroke (AIS) and it has been studied using in vitro and in silico models. Thrombectomy outcomes have been performed for patient-specific…

Medicine has taken a big jump in its advancement in the past few years. With the introduction of technology and the synthesis of personalized medicines, doctors have been successful in treating even the deadliest of the diseases. Though…

Medical Physics · Physics 2020-11-10 Puru Malhotra , Nimesh Shahdadpuri

Pulmonary embolism (PE) is a highly mortal disease, currently assessed by pulmonary CT angiography. True-FISP MRI has emerged as an innocuous alternative that does not hold many of the limitations of x-ray imaging. However, True-FISP MRI is…

Computer Vision and Pattern Recognition · Computer Science 2017-09-26 Luis R Soenksen , Luis Jiménez-Angeles , Gabriela Melendez , Aloha Meave

Blood clots occur in the human body when they are required to prevent bleeding. In pathological states such as diabetes and sickle cell disease, blood clots can also form undesirably due to hypercoagulable plasma conditions. With the…

Biological Physics · Physics 2021-10-05 Tyler Scogin , Sumith Yesudasan , Mitchell L. R. Walker , Rodney D. Averett

Ventricular fibrillation, the major reason behind sudden cardiac death, is turbulent cardiac electrical activity in which rapid, irregular disturbances in the spatiotemporal electrical activation of the heart makes it incapable of any…

Chaotic Dynamics · Physics 2009-11-07 Sitabhra Sinha , Ashwin Pande , Rahul Pandit

May-Thurner Syndrome (MTS) is a vascular condition that affects over 20\% of the population and significantly increases the risk of iliofemoral deep venous thrombosis. Accurate and early diagnosis of MTS using computed tomography (CT)…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yixin Huang , Yiqi Jin , Ke Tao , Kaijian Xia , Jianfeng Gu , Lei Yu , Haojie Li , Lan Du , Cunjian Chen

A new approach to prevent spurious behavior caused by conventional shock-capturing schemes when solving stiff detonation waves problems is introduced in the present work. Due to smearing of discontinuous solution by the excessive numerical…

Computational Physics · Physics 2017-08-04 Xi Deng , Honghui Teng , Bin Xie , Feng Xiao

Aspiration thrombectomy is a treatment option for ischemic stroke due to occlusions in large vessels. During the therapy a device is inserted into the vessel and suction is applied. A new one-dimensional model is introduced that is capable…

Numerical Analysis · Mathematics 2024-03-11 Michael Herty , Niklas Kolbe , Michael Neidlin

Ischemia leading to heart attacks and strokes is the major cause of deaths in the world. Whether an occlusion occurs or not, depends on the ability of a growing thrombus to resist forces exerted on its structure. This manuscript provides…

Cell Behavior · Quantitative Biology 2019-01-16 Olufemi Emmanuel Kadri , Vishnu Deep Chandran , Migle Surblyte , Roman S. Voronov

Kidney stones can cause severe pain and complications such as chronic kidney disease or kidney failure. Retrograde intrarenal surgery (RIRS), which uses laser lithotripsy to fragment stones for removal via a ureteroscope, is widely adopted…

Applied Physics · Physics 2025-04-17 Yilong Chang , Jasmine Vallejo , Yangqing Sun , Ruike Renee Zhao

Subclinical leaflet thrombosis (SLT) is a potentially serious complication of aortic valve replacement with a bioprosthetic valve in which blood clots form on the replacement valve. SLT is associated with increased risk of transient…

Small-scale robots offer significant potential in minimally-invasive medical procedures. Due to the nature of soft biological tissues, however, robots are exposed to complex environments with various challenges in locomotion, which is…

Robotics · Computer Science 2025-02-28 Moonkwang Jeon , Xiangzhou Tan , Felix Fischer , Tian Qiu

Patients suffering chronic severe pulmonary thromboembolism need Pulmonary Thromboendarterectomy (PTE) to remove the thromb and intima located inside pulmonary artery (PA). During the surgery, a surgeon holds tweezers and a dissector to…

Robotics · Computer Science 2026-02-04 Runfeng Zhu , Xin Zhong , Qingxiang Zhao , Jing Lin , Zhong Wu , Kang Li

Dried blood spot (DBS) has risen in popularity due to the ease of sampling, storing, shipping and more. Despite those advantages, recovery of the dried blood in solution for analysis is still a bottleneck as it is manual, time-consuming and…

An innovative two-stage methodology for categorizing blood clot origins is presented in this paper, which is important for the diagnosis and treatment of ischemic stroke. First, a background classifier based on MobileNetV3 segments big…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Koushik Sivarama Krishnan , P. J. Joe Nikesh , Swathi Gnanasekar , Karthik Sivarama Krishnan
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