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Likelihood methods for measuring statistical evidence obey the likelihood principle while maintaining bounded and well-controlled frequency properties. These methods lend themselves to sequential study designs because they measure the…

Methodology · Statistics 2017-11-07 Jeffrey D Blume , Leena Choi

During the COVID-19 pandemic, the sheer volume of imaging performed in an emergency setting for COVID-19 diagnosis has resulted in a wide variability of clinical CXR acquisitions. This variation is seen in the CXR projections used, image…

With the spread of COVID-19 over the world, the need arose for fast and precise automatic triage mechanisms to decelerate the spread of the disease by reducing human efforts e.g. for image-based diagnosis. Although the literature has shown…

We study the population size time series of a Neotropical small mammal with the intent of detecting and modelling population regulation processes generated by density-dependent factors and their possible delayed effects. The application of…

Populations and Evolution · Quantitative Biology 2017-02-20 E. Brigatti , M. V. Vieira , M. Kajin , P. J. A. L. Almeida , M. A. de Menezes , R. Cerqueira

Updating observations of a signal due to the delays in the measurement process is a common problem in signal processing, with prominent examples in a wide range of fields. An important example of this problem is the nowcasting of COVID-19…

We present a robust data-driven machine learning analysis of the COVID-19 pandemic from its early infection dynamics, specifically infection counts over time. The goal is to extract actionable public health insights. These insights include…

Populations and Evolution · Quantitative Biology 2020-04-06 Malik Magdon-Ismail

The COVID-19 pandemic represents the most significant public health disaster since the 1918 influenza pandemic. During pandemics such as COVID-19, timely and reliable spatio-temporal forecasting of epidemic dynamics is crucial. Deep…

Machine Learning · Computer Science 2020-11-25 Lijing Wang , Aniruddha Adiga , Srinivasan Venkatramanan , Jiangzhuo Chen , Bryan Lewis , Madhav Marathe

Phenomenological and deterministic models are often used for the estimation of transmission parameters in an epidemic and for the prediction of its growth trajectory. Such analyses are usually based on single peak outbreak dynamics. In…

Populations and Evolution · Quantitative Biology 2022-01-20 D. P. Mahapatra , S. Triambak

Epidemics and pandemics have ravaged human life since time. To combat these, novel ideas have always been created and deployed by humanity, with varying degrees of success. At this very moment, the COVID-19 pandemic is the singular global…

Accurate forecasts for COVID-19 are necessary for better preparedness and resource management. Specifically, deciding the response over months or several months requires accurate long-term forecasts which is particularly challenging as the…

Populations and Evolution · Quantitative Biology 2020-07-10 Ajitesh Srivastava , Viktor K. Prasanna

During the outbreak of COVID-19 pandemic, several research areas joined efforts to mitigate the damages caused by SARS-CoV-2. In this paper we present an interpretability analysis of a convolutional neural network based model for COVID-19…

COVID-19 had a strong and disruptive impact on our society, and yet further analyses on most relevant factors explaining the spread of the pandemic are needed. Interdisciplinary studies linking epidemiological, mobility, environmental, and…

We present a workflow for clinical data analysis that relies on Bayesian Structure Learning (BSL), an unsupervised learning approach, robust to noise and biases, that allows to incorporate prior medical knowledge into the learning process…

Machine Learning · Computer Science 2022-10-12 Elisa Ferrari , Luna Gargani , Greta Barbieri , Lorenzo Ghiadoni , Francesco Faita , Davide Bacciu

We propose a novel approach that integrates machine learning into compartmental disease modeling to predict the progression of COVID-19. Our model is explainable by design as it explicitly shows how different compartments evolve and it uses…

Statistical inference of evolutionary parameters from molecular sequence data relies on coalescent models to account for the shared genealogical ancestry of the samples. However, inferential algorithms do not scale to available data sets. A…

Applications · Statistics 2019-09-10 Lorenzo Cappello , Julia A. Palacios

Serology testing can identify past infection by quantifying the immune response of an infected individual providing important public health guidance. Individual immune responses are time-dependent, which is reflected in antibody…

Quantitative Methods · Quantitative Biology 2022-08-04 Prajakta Bedekar , Anthony J. Kearsley , Paul N. Patrone

The collection of large, complex datasets has become common across a wide variety of domains. Visual analytics tools increasingly play a key role in exploring and answering complex questions about these large datasets. However, many…

Human-Computer Interaction · Computer Science 2020-06-19 David Borland , Wenyuan Wang , Jonathan Zhang , Joshua Shrestha , David Gotz

The prediction of phenotypic traits using high-density genomic data has many applications such as the selection of plants and animals of commercial interest; and it is expected to play an increasing role in medical diagnostics. Statistical…

Methodology · Statistics 2016-09-29 Marco Scutari , Ian Mackay , David Balding

COVID-19 is a global health crisis that has had unprecedented, widespread impact on households across the United States and has been declared a global pandemic on March 11, 2020 by World Health Organization (WHO) [1]. According to Centers…

Systems and Control · Electrical Eng. & Systems 2021-10-25 Harshvardhan Uppaluru , Hamid Emadi , Hossein Rastgoftar

We consider the problem of inference for the states and parameters of a continuous-time multitype branching process from partially observed time series data. Exact inference for this class of models, typically using sequential Monte Carlo,…

Methodology · Statistics 2025-12-01 Angus Lewis , Antonio Parrella , John Maclean , Andrew J. Black
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