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Acanthamoebae are free-living protists and human pathogens, whose cellular functions and pathogenicity strongly depend on the transport of intracellular vesicles and granules through the cytosol. Using high-speed live cell imaging in…

Biological Physics · Physics 2015-07-03 J. F. Reverey , J. -H. Jeon , H. Bao , M. Leippe , R. Metzler , C. Selhuber-Unkel

We study the dynamics of a model of membrane vesicle transport into dendritic spines, which are bulbous intracellular compartments in neurons driven by molecular motors. We reduce the lubrication model proposed in [Fai et al., Active…

Cell Behavior · Quantitative Biology 2020-11-19 Youngmin Park , Thomas G. Fai

This paper is concerned with a non-homogeneous in space and non-local in time random walk model for anomalous subdiffusive transport of cells. Starting with a Markov model involving a structured probability density function, we derive the…

Statistical Mechanics · Physics 2013-02-21 S. Fedotov , A. O. Ivanov , A. Y. Zubarev

We study the persistent random walk of photons on a one-dimensional lattice of random asymmetric transmittances. Each site is characterized by its intensity transmittance t (t') for photons moving to the right (left) direction.…

Statistical Mechanics · Physics 2012-03-19 Zeinab Sadjadi , MirFaez Miri

A quantitative understanding of organism-level behavior requires predictive models that can capture the richness of behavioral phenotypes, yet are simple enough to connect with underlying mechanistic processes. Here we investigate the…

Neurons and Cognition · Quantitative Biology 2019-03-26 Stephen J. Helms , W. Mathijs Rozemuller , Antonio Carlos Costa , Leon Avery , Greg J. Stephens , Thomas S. Shimizu

The electrodynamic response of DNA in the millimeter wave range is investigated. By performing measurements under a wide range of humidity conditions and comparing the response of single strand DNA and double strand DNA, we show that the…

Disordered Systems and Neural Networks · Physics 2015-06-24 M. Briman , N. P. Armitage , E. Helgren , G. Gruner

Anomalous transport processes in which the variance of the distance travelled does not necessarily increase linearly with time are modelled using the formalism of continuous time random walks. We compute particle propagators which have the…

Astrophysics · Physics 2011-05-23 B. R. Ragot , J. G. Kirk

The L\'evy walk process with rests is discussed. The jumping time is governed by an $\alpha$-stable distribution with $\alpha>1$ while a waiting time distribution is Poissonian and involves a position-dependent rate which reflects a…

Statistical Mechanics · Physics 2017-10-11 A. Kamińska , T. Srokowski

It is well known that, during replication, RNA viruses spontaneously generate defective viral genomes (DVGs). DVGs are unable to complete an infectious cycle autonomously, and depend on coinfection with a helper wild-type virus (HV) for…

Cells move differently on substrates with different elasticities. In particular, the persistence time of their motion is higher on stiffer substrates. We show that this behavior will result in a net transport of cells directed up a…

Biological Physics · Physics 2017-03-09 Elizaveta A. Novikova , Matthew Raab , Dennis E. Discher , Cornelis Storm

We experimentally investigate the transmission of light by dense atomic vapor. The light propagating in dense atomic vapor can be modeled as a L\'evy flight random walk. For such system, the step-length distribution can be modeled as…

In cellular vortical flows, namely arrays of counter-rotating vortices, short but flexible filaments can show simple random walks through their stretch-coil interactions with flow stagnation points. Here, we study the dynamics of semi-rigid…

Soft Condensed Matter · Physics 2021-08-18 Shi-Yuan Hu , Jun-Jun Chu , Michael J. Shelley , Jun Zhang

Based on experimental observations it is known that various biological cells exhibit a persistent random walk during migration on flat substrates. The persistent random walk is characterized by `stop-and-go' movements : unidirectional…

Subcellular Processes · Quantitative Biology 2009-11-11 B. Nandy , A. Baumgaertner

Transport in disordered systems often occurs via the variable range hopping (VRH) in the dilute carrier density limit, where electrons hop between randomly distributed localized levels. We study the nonequilibrium transport by a uniform DC…

Disordered Systems and Neural Networks · Physics 2025-09-24 Kunal Mozumdar , Herbert F. Fotso , Jong E. Han

We study the spreading of initially localized excitations in 1D disordered granular crystals. We thereby investigate localization phenomena in strongly nonlinear systems, which we demonstrate to be fundamentally different from localization…

Disordered Systems and Neural Networks · Physics 2016-02-17 Alejandro J. Martínez , P. G. Kevrekidis , Mason A. Porter

The movement of organisms and cells can be governed by occasional long distance runs, according to an approximate L\'evy walk. For T cells migrating through chronically-infected brain tissue, runs are further interrupted by long pauses, and…

Biological Physics · Physics 2020-03-06 Gissell Estrada-Rodriguez , Heiko Gimperlein , Kevin J. Painter , Jakub Stocek

A model for the unidirectional movement of dynein is presented based on structural observations and biochemical experimental results available. In this model, the binding affinity of dynein for microtubule is independent of its nucleotide…

Biomolecules · Quantitative Biology 2007-08-18 Ping Xie , Shuo-Xing Dou , Peng-Ye Wang

We introduce a persistent random walk model for the stochastic transport of particles involving self-reinforcement and a rest state with Mittag-Leffler distributed residence times. The model involves a system of hyperbolic partial…

Statistical Mechanics · Physics 2021-11-16 Daniel Han , Dmitri V. Alexandrov , Anna Gavrilova , Sergei Fedotov

Motivated by studies on the recurrent properties of animal and human mobility, we introduce a path-dependent random walk model with long range memory for which not only the mean square displacement (MSD) can be obtained exactly in the…

Statistical Mechanics · Physics 2015-06-19 D. Boyer , J. C. R. Romo-Cruz

We demonstrate the phenomenon of cumulative inertia in intracellular transport involving multiple motor proteins in human epithelial cells by measuring the empirical survival probability of cargoes on the microtubule and their detachment…

Statistical Mechanics · Physics 2018-10-31 Sergei Fedotov , Nickolay Korabel , Thomas A. Waigh , Daniel Han , Victoria J. Allan
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