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Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

Genomics · Quantitative Biology 2016-03-08 Dan Ofer

The growing Synthetic Aperture Radar (SAR) data has the potential to build a foundation model through Self-Supervised Learning (SSL) methods, which can achieve various SAR Automatic Target Recognition (ATR) tasks with pre-training in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Weijie Li , Yang Wei , Tianpeng Liu , Yuenan Hou , Yuxuan Li , Zhen Liu , Yongxiang Liu , Li Liu

Answer Set Programming (ASP) is a prominent problem-modeling and solving framework, whose solutions are called answer sets. Epistemic logic programs (ELP) extend ASP to reason about all or some answer sets. Solutions to an ELP can be seen…

Logic in Computer Science · Computer Science 2025-03-10 Thomas Eiter , Johannes K. Fichte , Markus Hecher , Stefan Woltran

Predicting a structure of an antibody from its sequence is important since it allows for a better design process of synthetic antibodies that play a vital role in the health industry. Most of the structure of an antibody is conservative.…

Biomolecules · Quantitative Biology 2021-12-23 Natalia Zenkova , Ekaterina Sedykh , Tatiana Shugaeva , Vladislav Strashko , Timofei Ermak , Aleksei Shpilman

Anticancer peptides (ACPs) are a class of molecules that have gained significant attention in the field of cancer research and therapy. ACPs are short chains of amino acids, the building blocks of proteins, and they possess the ability to…

Biomolecules · Quantitative Biology 2024-01-05 Zeynep Hilal Kilimci , Mustafa Yalcin

Accurate phase estimation at the edge of data segments is crucial for EEG applications such as EEG-TMS in offline and real-time data analysis. Our research evaluates the phase estimation performance of four commonly used methods…

Neurons and Cognition · Quantitative Biology 2026-04-03 Miriam Kirchhoff , Johanna Rösch , Maria Ermolova , Oskari Ahola , Sarah Harders , Juliana Hougland , Ulf Ziemann

Unsupervised learning of vision transformers seeks to pretrain an encoder via pretext tasks without labels. Among them is the Masked Image Modeling (MIM) aligned with pretraining of language transformers by predicting masked patches as a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Xiao Wang , Ying Wang , Ziwei Xuan , Guo-Jun Qi

Significant progress has been made in semi-supervised hyperspectral image (HSI) classification regarding feature extraction and classification performance. However, due to high annotation costs and limited sample availability,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Yunfei Qiu , Qiqiong Ma , Tianhua Lv , Li Fang , Shudong Zhou , Wei Yao

Preparticipation cardiovascular examination (PPCE) aims to prevent sudden cardiac death (SCD) by identifying athletes with structural or electrical cardiac abnormalities. Anthropometric measurements, such as waist circumference, limb…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Lucas R. Mareque , Ricardo L. Armentano , Leandro J. Cymberknop

Analogy-based effort estimation (ABE) is one of the efficient methods for software effort estimation because of its outstanding performance and capability of handling noisy datasets. Conventional ABE models usually use the same number of…

Software Engineering · Computer Science 2017-03-20 Mohammad Azzeh , Ali Bou Nassif

Affinity maturation produces antibodies that bind antigens with high specificity by accumulating mutations in the antibody sequence. Mapping out the antibody-antigen affinity landscape can give us insight into the accessible paths during…

Populations and Evolution · Quantitative Biology 2019-05-14 Rhys M. Adams , Justin B. Kinney , Aleksandra M. Walczak , Thierry Mora

Byte-Pair Encoding (BPE) has become a widely adopted subword tokenization method in modern language models due to its simplicity and strong empirical performance across downstream tasks. However, applying BPE to unsegmented languages such…

Computation and Language · Computer Science 2025-06-23 Yifan Hu , Frank Liang , Dachuan Zhao , Jonathan Geuter , Varshini Reddy , Craig W. Schmidt , Chris Tanner

Antibodies are Y-shaped proteins that neutralize pathogens and constitute the core of our adaptive immune system. De novo generation of new antibodies that target specific antigens holds the key to accelerating vaccine discovery. However,…

Machine Learning · Computer Science 2023-06-05 Yogesh Verma , Markus Heinonen , Vikas Garg

Antinuclear antibody (ANA) testing is a crucial method for diagnosing autoimmune disorders, including lupus, Sj\"ogren's syndrome, and scleroderma. Despite its importance, manual ANA detection is slow, labor-intensive, and demands years of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Yiyang Jiang , Guangwu Qian , Jiaxin Wu , Qi Huang , Qing Li , Yongkang Wu , Xiao-Yong Wei

Bayesian decision theory advocates the Bayes classifier as the optimal approach for minimizing the risk in machine learning problems. Current deep learning algorithms usually solve for the optimal classifier by \emph{implicitly} estimating…

Machine Learning · Computer Science 2025-07-01 Chaoqun Du , Yulin Wang , Shiji Song , Gao Huang

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

Accurate prediction of enzyme function is crucial for elucidating biological mechanisms and driving innovation across various sectors. Existing deep learning methods tend to rely solely on either sequence data or structural data and predict…

Quantitative Methods · Quantitative Biology 2024-08-14 Dingyi Rong , Wenzhuo Zheng , Bozitao Zhong , Zhouhan Lin , Liang Hong , Ning Liu

Automatic polyp segmentation is helpful to assist clinical diagnosis and treatment. In daily clinical practice, clinicians exhibit robustness in identifying polyps with both location and size variations. It is uncertain if deep segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Runpu Wei , Zijin Yin , Kongming Liang , Min Min , Chengwei Pan , Gang Yu , Haonan Huang , Yan Liu , Zhanyu Ma

Deep learning techniques are increasingly being adopted in diagnostic medical imaging. However, the limited availability of high-quality, large-scale medical datasets presents a significant challenge, often necessitating the use of transfer…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Heba El-Shimy , Hind Zantout , Michael A. Lones , Neamat El Gayar

The Epithelial Dysplasia (ED) is a tissue alteration commonly present in lesions preceding oral cancer, being its presence one of the most important factors in the progression toward carcinoma. This study proposes a method to design a low…

Image and Video Processing · Electrical Eng. & Systems 2022-04-08 Karoline da Rocha , José C. M. Bermudez , Elena R. C. Rivero , Márcio H. Costa