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Ontology development methodologies emphasise knowledge gathering from domain experts and documentary resources, and knowledge representation using an ontology language such as OWL or FOL. However, working ontologists are often surprised by…

Artificial Intelligence · Computer Science 2023-01-11 Fabian Neuhaus , Janna Hastings

Ontology learning in complex domains, such as life sciences, poses significant challenges for current Large Language Models (LLMs). Existing LLMs struggle to generate ontologies with multiple hierarchical levels, rich interconnections, and…

Artificial Intelligence · Computer Science 2024-12-04 Nadeen Fathallah , Steffen Staab , Alsayed Algergawy

Ontology Matching (OM), is a critical task in knowledge integration, where aligning heterogeneous ontologies facilitates data interoperability and knowledge sharing. Traditional OM systems often rely on expert knowledge or predictive…

Artificial Intelligence · Computer Science 2024-04-24 Hamed Babaei Giglou , Jennifer D'Souza , Felix Engel , Sören Auer

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

Large Language Models (LLMs) are advancing at a rapid pace, with significant improvements at natural language processing and coding tasks. Yet, their ability to work with formal languages representing data, specifically within the realm of…

Artificial Intelligence · Computer Science 2023-10-02 Johannes Frey , Lars-Peter Meyer , Natanael Arndt , Felix Brei , Kirill Bulert

Managing scientific names in ontologies that represent species taxonomies is challenging due to the ever-evolving nature of these taxonomies. Manually maintaining these names becomes increasingly difficult when dealing with thousands of…

Ontology matching (OM) plays an essential role in enabling semantic interoperability and integration across heterogeneous knowledge sources, particularly in the biomedical domain which contains numerous complex concepts related to diseases…

Artificial Intelligence · Computer Science 2026-04-03 Yiping Song , Jiaoyan Chen , Renate A. Schmidt

Objective: Clinical deep phenotyping and phenotype annotation play a critical role in both the diagnosis of patients with rare disorders as well as in building computationally-tractable knowledge in the rare disorders field. These processes…

In this research short, we examine the potential of using GPT-4o, a state-of-the-art large language model (LLM) to undertake evidence synthesis and systematic assessment tasks. Traditional workflows for such tasks involve large groups of…

Computation and Language · Computer Science 2024-07-19 Elphin Tom Joe , Sai Dileep Koneru , Christine J Kirchhoff

Ontologies of research topics are crucial for structuring scientific knowledge, enabling scientists to navigate vast amounts of research, and forming the backbone of intelligent systems such as search engines and recommendation systems.…

Digital Libraries · Computer Science 2025-06-12 Tanay Aggarwal , Angelo Salatino , Francesco Osborne , Enrico Motta

Large Language Models (LLMs) have been extensively adopted in Knowledge Graph Completion (KGC), showcasing significant research advancements. However, as black-box models driven by deep neural architectures, current LLM-based KGC methods…

Computation and Language · Computer Science 2025-10-22 Wenbin Guo , Xin Wang , Jiaoyan Chen , Zhao Li , Zirui Chen

By leveraging GPT-4 for ontology narration, we developed GPTON to infuse structured knowledge into LLMs through verbalized ontology terms, achieving accurate text and ontology annotations for over 68% of gene sets in the top five…

Quantitative Methods · Quantitative Biology 2024-10-18 Rongbin Li , Wenbo Chen , Jinbo Li , Hanwen Xing , Hua Xu , Zhao Li , W. Jim Zheng

In the fast-evolving domain of artificial intelligence, large language models (LLMs) such as GPT-3 and GPT-4 are revolutionizing the landscapes of finance, healthcare, and law: domains characterized by their reliance on professional…

Computation and Language · Computer Science 2024-11-25 Zhiyu Zoey Chen , Jing Ma , Xinlu Zhang , Nan Hao , An Yan , Armineh Nourbakhsh , Xianjun Yang , Julian McAuley , Linda Petzold , William Yang Wang

The conventional process of building Ontologies and Knowledge Graphs (KGs) heavily relies on human domain experts to define entities and relationship types, establish hierarchies, maintain relevance to the domain, fill the ABox (or populate…

Computation and Language · Computer Science 2024-03-14 Vamsi Krishna Kommineni , Birgitta König-Ries , Sheeba Samuel

The emergence of Generative Artificial Intelligence (AI) and Large Language Models (LLMs) has marked a new era of Natural Language Processing (NLP), introducing unprecedented capabilities that are revolutionizing various domains. This paper…

Computation and Language · Computer Science 2024-08-26 Desta Haileselassie Hagos , Rick Battle , Danda B. Rawat

Generative Pre-trained Transformer 4 (GPT-4) is the fourth-generation language model in the GPT series, developed by OpenAI, which promises significant advancements in the field of natural language processing (NLP). In this research…

Computation and Language · Computer Science 2023-05-08 Jawid Ahmad Baktash , Mursal Dawodi

Ontologies have been known for their semantic representation of knowledge. ontologies cannot automatically evolve to reflect updates that occur in respective domains. To address this limitation, researchers have called for automatic…

Artificial Intelligence · Computer Science 2022-01-19 Samaa Elnagar , Victoria Yoon , Manoj A. Thomas

We addressed the problem of a lack of semantic representation for user-centric explanations and different explanation types in our Explanation Ontology (https://purl.org/heals/eo). Such a representation is increasingly necessary as…

Artificial Intelligence · Computer Science 2020-10-06 Shruthi Chari , Oshani Seneviratne , Daniel M. Gruen , Morgan A. Foreman , Amar K. Das , Deborah L. McGuinness

This work presents an ontology-integrated large language model (LLM) framework for chemical engineering that unites structured domain knowledge with generative reasoning. The proposed pipeline aligns model training and inference with the…

Machine Learning · Computer Science 2025-12-15 Crystal Su , Kuai Yu , Jingrui Zhang , Mingyuan Shao , Daniel Bauer

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser