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Digital Breast Tomosynthesis (DBT) is a widely used medical imaging modality for breast cancer screening and diagnosis, offering higher spatial resolution and greater detail through its 3D-like breast volume imaging capability. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Yuexi Du , Regina J. Hooley , John Lewin , Nicha C. Dvornek

Mammography-based screening has helped reduce the breast cancer mortality rate, but has also been associated with potential harms due to low specificity, leading to unnecessary exams or procedures, and low sensitivity. Digital breast…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sadanand Singh , Thomas Paul Matthews , Meet Shah , Brent Mombourquette , Trevor Tsue , Aaron Long , Ranya Almohsen , Stefano Pedemonte , Jason Su

The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…

Digital Breast Tomosynthesis (DBT) provides an insight into the fine details of normal fibroglandular tissues and abnormal lesions by reconstructing a pseudo-3D image of the breast. In this respect, DBT overcomes a major limitation of…

Computer Vision and Pattern Recognition · Computer Science 2013-07-24 Guang Yang , John H. Hipwell , David J. Hawkes , Simon R. Arridge

Full Field Digital Mammograms (FFDMs) and Digital Breast Tomosynthesis (DBT) are the two most widely used imaging modalities for breast cancer screening. Although DBT has increased cancer detection compared to FFDM, its widespread adoption…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Umang Sharma , Jungkyu Park , Laura Heacock , Sumit Chopra , Krzysztof Geras

Digital Breast Tomosynthesis (DBT) enhances finding visibility for breast cancer detection by providing volumetric information that reduces the impact of overlapping tissues; however, limited annotated data has constrained the development…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Yen Nhi Truong Vu , Dan Guo , Sripad Joshi , Harshit Kumar , Jason Su , Thomas Paul Matthews

Foundation models have shown promise in medical imaging but remain underexplored for three-dimensional imaging modalities. No foundation model currently exists for Digital Breast Tomosynthesis (DBT), despite its use for breast cancer…

When developing Computer Aided Detection (CAD) systems for Digital Breast Tomosynthesis (DBT), the complexity arising from the volumetric nature of the modality poses significant technical challenges for obtaining large-scale accurate…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Laurent Dillard , Hyeonsoo Lee , Weonsuk Lee , Tae Soo Kim , Ali Diba , Thijs Kooi

The segmentation of mass lesions in digital breast tomosynthesis (DBT) images is very significant for the early screening of breast cancer. However, the high-density breast tissue often leads to high concealment of the mass lesions, which…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Haoxuan Zhang , Wenju Cui , Yuzhu Cao , Tao Tan , Jie Liu , Yunsong Peng , Jian Zheng

Digital breast tomosynthesis (DBT) is an emerging modality for breast imaging. A typical tomosynthesis image is reconstructed from projection data acquired at a limited number of views over a limited angular range. In general, the…

Medical Physics · Physics 2009-08-19 I. Reiser , J. Bian , R. M. Nishikawa , E. Y. Sidky , X. Pan

Multimodal learning that integrates genomics and histopathology has shown strong potential in cancer diagnosis, yet its clinical translation is hindered by the limited availability of paired histology-genomics data. Knowledge distillation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Yongxin Guo , Hao Lu , Onur C. Koyun , Zhengjie Zhu , Muhammet Fatih Demir , Metin Nafi Gurcan

Breast cancer screening is one of the most common radiological tasks with over 39 million exams performed each year. While breast cancer screening has been one of the most studied medical imaging applications of artificial intelligence, the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Mateusz Buda , Ashirbani Saha , Ruth Walsh , Sujata Ghate , Nianyi Li , Albert Święcicki , Joseph Y. Lo , Maciej A. Mazurowski

As early detection of breast cancer strongly favors successful therapeutic outcomes, there is major commercial interest in optimizing breast cancer screening. However, current risk prediction models achieve modest performance and do not…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Manon A. Dorster , Felix J. Dorfner , Mason C. Cleveland , Melisa S. Guelen , Jay Patel , Dania Daye , Jean-Philippe Thiran , Albert E. Kim , Christopher P. Bridge

Lesion detection in digital breast tomosynthesis (DBT) is an important and a challenging problem characterized by a low prevalence of images containing tumors. Due to the label scarcity problem, large deep learning models and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Yifan Zhang , Haoyu Dong , Nicholas Konz , Hanxue Gu , Maciej A. Mazurowski

Immunohistochemical (IHC) biomarker prediction benefits from multi-modal data fusion analysis. However, the simultaneous acquisition of multi-modal data, such as genomic and pathological information, is often challenging due to cost or…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Qibin Zhang , Xinyu Hao , Qiao Chen , Rui Xu , Fengyu Cong , Cheng Lu , Hongming Xu

Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

There is no doubt that advanced artificial intelligence models and high quality data are the keys to success in developing computational pathology tools. Although the overall volume of pathology data keeps increasing, a lack of quality data…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Trinh Thi Le Vuong , Jin Tae Kwak

This work presents a novel breast cancer imaging approach that uses compressive sensing in a hybrid Digital Breast Tomosynthesis (DBT) / Nearfield Radar Imaging (NRI) system configuration. The non-homogeneous tissue distribution of the…

Optimization and Control · Mathematics 2016-03-22 Richard Obermeier , Jose Angel Martinez Lorenzo

Recently, efficient Multimodal Large Language Models (MLLMs) have gained significant attention as a solution to their high computational complexity, making them more practical for real-world applications. In this regard, the knowledge…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Jiwan Kim , Kibum Kim , Sangwoo Seo , Chanyoung Park

Numerous self-supervised learning paradigms, such as contrastive learning and masked image modeling, have been proposed to acquire powerful and general representations from unlabeled data. However, these models are commonly pretrained…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Yuang Liu , Jing Wang , Qiang Zhou , Fan Wang , Jun Wang , Wei Zhang
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