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Early detection of dementia through specific biomarkers in MR images plays a critical role in developing support strategies proactively. Fazekas scale facilitates an accurate quantitative assessment of the severity of white matter lesions…

Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Simisola Odimayo , Chollette C. Olisah , Khadija Mohammed

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that predominantly affects the elderly population and currently has no cure. Magnetic Resonance Imaging (MRI), as a non-invasive imaging technique, is essential for the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Xinyue Yang , Meiliang Liu , Yunfang Xu , Xiaoxiao Yang , Zhengye Si , Zijin Li , Zhiwen Zhao

We present a proof-of-concept, deep learning (DL) based, differentiable biomechanical model of realistic brain deformations. Using prescribed maps of local atrophy and growth as input, the network learns to deform images according to a…

Machine Learning · Computer Science 2020-12-15 Mariana da Silva , Kara Garcia , Carole H. Sudre , Cher Bass , M. Jorge Cardoso , Emma Robinson

Deformable registration consists of finding the best dense correspondence between two different images. Many algorithms have been published, but the clinical application was made difficult by the high calculation time needed to solve the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Théo Estienne , Maria Vakalopoulou , Enzo Battistella , Theophraste Henry , Marvin Lerousseau , Amaury Leroy , Nikos Paragios , Eric Deutsch

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

With the increasing incidence of neurodegenerative diseases such as Alzheimer's Disease (AD), there is a need for further research that enhances detection and monitoring of the diseases. We present MORPHADE (Morphological Autoencoders for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Mehmet Yigit Avci , Emily Chan , Veronika Zimmer , Daniel Rueckert , Benedikt Wiestler , Julia A. Schnabel , Cosmin I. Bercea

Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Ahsan Bin Tufail , Qiu-Na Zhang , Yong-Kui Ma

Accurate diagnosis of brain disorders such as Alzheimer's disease and brain tumors remains a critical challenge in medical imaging. Conventional methods based on manual MRI analysis are often inefficient and error-prone. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Sumshun Nahar Eity , Mahin Montasir Afif , Tanisha Fairooz , Md. Mortuza Ahmmed , Md Saef Ullah Miah

Recent advances in deep learning have improved the segmentation accuracy of subcortical brain structures, which would be useful in neuroimaging studies of many neurological disorders. However, most of the previous deep learning work does…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Yilin Liu , Gengyan Zhao , Brendon M. Nacewicz , Nagesh Adluru , Gregory R. Kirk , Peter A Ferrazzano , Martin Styner , Andrew L. Alexander

Brain stroke is a leading cause of mortality and long-term disability worldwide, underscoring the need for precise and rapid prediction techniques. Computed Tomography (CT) scan is considered one of the most effective methods for diagnosing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Md. Sabbir Hossen , Eshat Ahmed Shuvo , Shibbir Ahmed Arif , Pabon Shaha , Anichur Rahman , Md. Saiduzzaman , Fahmid Al Farid , Hezerul Abdul Karim , Abu Saleh Musa Miah

Radiation therapy has emerged as one of the preferred techniques to treat brain cancer patients. During treatment, a very high dose of radiation is delivered to a very narrow area. Prescribed radiation therapy for brain cancer requires…

Computer Vision and Pattern Recognition · Computer Science 2017-04-06 Jose Dolz , Nicolas Reyns , Nacim Betrouni , Dris Kharroubi , Mathilde Quidet , Laurent Massoptier , Maximilien Vermandel

Dementia encompasses a group of syndromes that impair cognitive functions such as memory, reasoning, and the ability to perform daily activities. As populations globally age, over 10 million new dementia diagnoses are reported annually.…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-24 Marko Niemelä , Mikaela von Bonsdorff , Sami Äyrämö , Tommi Kärkkäinen

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

The evolution of deep learning and artificial intelligence has significantly reshaped technological landscapes. However, their effective application in crucial sectors such as medicine demands more than just superior performance, but…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yasmine Mustafa , Tie Luo

Multimodal 3D MRI brain tumor segmentation is a pivotal step in radiotherapy target delineation, surgical planning and post-treatment assessment. Existing methods often assume artifact-free MRI images. However, inevitable patient motion…

Image and Video Processing · Electrical Eng. & Systems 2026-05-18 Yuchun Wang , Xiaosong Li , Gefei Liang , Yang Liu

Introduction: Machine learning (ML) has been extremely successful in identifying key features from high-dimensional datasets and executing complicated tasks with human expert levels of accuracy or greater. Methods: We summarize and…

Magnetic resonance imaging (MRI) is a crucial medical imaging modality. However, long acquisition times remain a significant challenge, leading to increased costs, and reduced patient comfort. Recent studies have shown the potential of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Amirmohammad Shamaei , Alexander Stebner , Salome , Bosshart , Johanna Ospel , Gouri Ginde , Mariana Bento , Roberto Souza

Brain tumors, particularly glioblastoma, continue to challenge medical diagnostics and treatments globally. This paper explores the application of deep learning to multi-modality magnetic resonance imaging (MRI) data for enhanced brain…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Chiranjeewee Prasad Koirala , Sovesh Mohapatra , Advait Gosai , Gottfried Schlaug