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Related papers: SepsisLab: Early Sepsis Prediction with Uncertaint…

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Improper pain management can lead to severe physical or mental consequences, including suffering, and an increased risk of opioid dependency. Assessing the presence and severity of pain is imperative to prevent such outcomes and determine…

Machine Learning · Computer Science 2023-11-30 Burcu Ozek , Zhenyuan Lu , Srinivasan Radhakrishnan , Sagar Kamarthi

Monitoring the health status of patients and predicting mortality in advance is vital for providing patients with timely care and treatment. Massive medical signs in electronic health records (EHR) are fitted into advanced machine learning…

Machine Learning · Computer Science 2023-11-07 Xuesong Ye , Jun Wu , Chengjie Mou , Weinan Dai

Sepsis affects millions of people worldwide each year. It occurs when a normal human immune response to a bacterial, viral or fungal infection becomes dysfunctional and triggers widespread inflammation that results in severe tissue damage…

Tissues and Organs · Quantitative Biology 2016-09-26 Todd Gary , Damian Mingle , Ashwini Yenamandra

Although there has been significant research in boosting of weak learners, there has been little work in the field of boosting from strong learners. This latter paradigm is a form of weighted voting with learned weights. In this work, we…

Machine Learning · Computer Science 2020-12-22 Matthew A. Reyna , Gari D. Clifford

In this paper, we introduce SeizNet, a closed-loop system for predicting epileptic seizures through the use of Deep Learning (DL) method and implantable sensor networks. While pharmacological treatment is effective for some epilepsy…

Recent advances in deep learning (DL) have prompted the development of high-performing early warning score (EWS) systems, predicting clinical deteriorations such as acute kidney injury, acute myocardial infarction, or circulatory failure.…

Machine Learning · Computer Science 2025-02-05 Yuxiao Cheng , Xinxin Song , Ziqian Wang , Qin Zhong , Kunlun He , Jinli Suo

Machine learning for early prediction in medicine has recently shown breakthrough performance, however, the focus on improving prediction accuracy has led to a neglect of faithful explanations that are required to gain the trust of medical…

Computation and Language · Computer Science 2025-12-04 Michael Staniek , Artem Sokolov , Stefan Riezler

The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights into the underlying disease-driving mechanisms. In this…

Quantitative Methods · Quantitative Biology 2019-10-24 Pejman F. Ghalati , Satya S. Samal , Jayesh S. Bhat , Robert Deisz , Gernot Marx , Andreas Schuppert

Patient-reported outcome (PRO) measures are increasingly collected as a means of measuring healthcare quality and value. The capability to predict such measures enables patient-provider shared decision making and the delivery of…

Methodology · Statistics 2023-03-01 Jaeyoung Park , Muxuan Liang , Ying-Qi Zhao , Xiang Zhong

We propose a causal hidden Markov model to achieve robust prediction of irreversible disease at an early stage, which is safety-critical and vital for medical treatment in early stages. Specifically, we introduce the hidden variables which…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Jing Li , Botong Wu , Xinwei Sun , Yizhou Wang

Epilepsy is a chronic neurological disorder that affects a significant portion of the human population and imposes serious risks in the daily life of patients. Despite advances in machine learning and IoT, small, nonstigmatizing wearable…

Machine Learning · Computer Science 2023-02-22 Una Pale , Tomas Teijeiro , David Atienza

Seizure forecasting may provide patients with timely warnings to adapt their daily activities and help clinicians deliver more objective, personalized treatments. While recent work has convincingly demonstrated that seizure risk assessment…

Neurons and Cognition · Quantitative Biology 2019-06-10 Christian Meisel , Rima El Atrache , Michele Jackson , Sarah Schubach , Claire Ufongene , Tobias Loddenkemper

Sepsis is a life-threatening condition defined by end-organ dysfunction due to a dysregulated host response to infection. Although the Surviving Sepsis Campaign has launched and has been releasing sepsis treatment guidelines to unify and…

Machine Learning · Computer Science 2024-11-20 Hyewon Jeong , Siddharth Nayak , Taylor Killian , Sanjat Kanjilal

Causal inference from electronic health records (EHR) is fundamentally limited by unmeasured confounding: critical clinical states such as frailty, goals of care, and mental status are documented in free-text notes but absent from…

Machine Learning · Computer Science 2026-04-22 Lei Liu , Jialin Chen , Kathy Macropol

Epistemic Uncertainty is a measure of the lack of knowledge of a learner which diminishes with more evidence. While existing work focuses on using the variance of the Bayesian posterior due to parameter uncertainty as a measure of epistemic…

Deep learning (DL) can aid doctors in detecting worsening patient states early, affording them time to react and prevent bad outcomes. While DL-based early warning models usually work well in the hospitals they were trained for, they tend…

Machine Learning · Computer Science 2023-04-11 Patrick Rockenschaub , Adam Hilbert , Tabea Kossen , Falk von Dincklage , Vince Istvan Madai , Dietmar Frey

Methods to detect the emergence of infectious diseases, and approach to the "critical transition" RE = 1, have to potential to avert substantial disease burden by facilitating preemptive actions like vaccination campaigns. Early warning…

Other Quantitative Biology · Quantitative Biology 2025-04-16 Callum R. K. Arnold , Matthew J. Ferrari

Hospitals lack automated systems to harness the growing volume of heterogeneous clinical and operational data to effectively forecast critical events. Early identification of patients at risk for deterioration is essential not only for…

Uncertainty estimation, which provides a means of building explainable neural networks for medical imaging applications, have mostly been studied for single deep learning models that focus on a specific task. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Leonhard F. Feiner , Martin J. Menten , Kerstin Hammernik , Paul Hager , Wenqi Huang , Daniel Rueckert , Rickmer F. Braren , Georgios Kaissis

Causal inference with observational studies often relies on the assumptions of unconfoundedness and overlap of covariate distributions in different treatment groups. The overlap assumption is violated when some units have propensity scores…

Methodology · Statistics 2022-07-19 Shu Yang , Peng Ding