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Related papers: SepsisLab: Early Sepsis Prediction with Uncertaint…

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Sepsis is a syndrome that develops in the body in response to the presence of an infection. Characterized by severe organ dysfunction, sepsis is one of the leading causes of mortality in Intensive Care Units (ICUs) worldwide. These…

Machine Learning · Computer Science 2023-11-20 Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

Machine Learning · Computer Science 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Machine Learning · Computer Science 2025-01-03 Arseniy Shumilov , Yueting Zhu , Negin Ashrafi , Armin Abdollahi , Greg Placencia , Kamiar Alaei , Maryam Pishgar

Timely and interpretable early warning of sepsis remains a major clinical challenge due to the complex temporal dynamics of physiological deterioration. Traditional data-driven models often provide accurate yet opaque predictions, limiting…

Machine Learning · Computer Science 2026-04-24 Weizhi Nie , Zhen Qu , Weijie Wang , Chunpei Li , Ke Lu , Bingyang Zhou , Hongzhi Yu

Interest in an electronic health record-based computational model that can accurately predict a patient's risk of sepsis at a given point in time has grown rapidly in the last several years. Like other EHR vendors, the Epic Systems…

Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…

Machine Learning · Computer Science 2025-02-19 Bruno Petrungaro , Neville K. Kitson , Anthony C. Constantinou

Sepsis is a lethal syndrome of organ dysfunction that is triggered by an infection and claims 11 million lives per year globally. Prognostic algorithms based on deep learning have shown promise in detecting the onset of sepsis hours before…

Tissues and Organs · Quantitative Biology 2024-08-19 Marco Giordano , Kanika Dheman , Michele Magno

Electronic health records (EHR) are characterized as non-stationary, heterogeneous, noisy, and sparse data; therefore, it is challenging to learn the regularities or patterns inherent within them. In particular, sparseness caused mostly by…

Machine Learning · Computer Science 2020-03-03 Eunji Jun , Ahmad Wisnu Mulyadi , Jaehun Choi , Heung-Il Suk

Sepsis is a life-threatening condition that seriously endangers millions of people over the world. Hopefully, with the widespread availability of electronic health records (EHR), predictive models that can effectively deal with clinical…

Machine Learning · Computer Science 2019-10-16 Luchen Liu , Haoxian Wu , Zichang Wang , Zequn Liu , Ming Zhang

Sepsis is a life-threatening syndrome with high morbidity and mortality in hospitals. Early prediction of sepsis plays a crucial role in facilitating early interventions for septic patients. However, early sepsis prediction systems with…

Machine Learning · Computer Science 2025-03-20 Anni Zhou , Beyah Raheem , Rishikesan Kamaleswaran , Yao Xie

We develop and analyze explainable machine learning (ML) models for sepsis outcome prediction using a novel Electronic Health Record (EHR) dataset from 12,286 hospitalizations at a large emergency hospital in Romania. The dataset includes…

Machine Learning · Computer Science 2026-04-07 Andrei-Alexandru Bunea , Ovidiu Ghibea , Dan-Matei Popovici , Ion Daniel , Octavian Andronic

Sepsis is a potentially life threatening inflammatory response to infection or severe tissue damage. It has a highly variable clinical course, requiring constant monitoring of the patient's state to guide the management of intravenous…

Machine Learning · Computer Science 2022-02-21 Thesath Nanayakkara , Gilles Clermont , Christopher James Langmead , David Swigon

This study proposes the use of Machine Learning models to predict the early onset of sepsis using deidentified clinical data from Montefiore Medical Center in Bronx, NY, USA. A supervised learning approach was adopted, wherein an XGBoost…

Sepsis is a life-threatening condition affecting over 48.9 million people globally and causing 11 million deaths annually. Despite medical advancements, predicting sepsis remains a challenge due to non-specific symptoms and complex…

Machine Learning · Computer Science 2025-05-30 Dharambir Mahto , Prashant Yadav , Mahesh Banavar , Jim Keany , Alan T Joseph , Srinivas Kilambi

Sepsis is a leading cause of death in the Intensive Care Units (ICU). Early detection of sepsis is critical for patient survival. In this paper, we propose a multimodal Transformer model for early sepsis prediction, using the physiological…

Machine Learning · Computer Science 2022-03-29 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

Machine Learning · Computer Science 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

Sepsis is a leading cause of mortality and critical illness worldwide. While robust biomarkers for early diagnosis are still missing, recent work indicates that hyperspectral imaging (HSI) has the potential to overcome this bottleneck by…

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

Machine Learning · Computer Science 2019-03-07 Avijit Mitra , Khalid Ashraf

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Machine Learning · Computer Science 2026-02-04 Yin Jin , Tucker R. Stewart , Deyi Zhou , Chhavi Gupta , Arjita Nema , Scott C. Brakenridge , Grant E. O'Keefe , Juhua Hu

Motivated by an observational study of the effect of hospital ward versus intensive care unit admission on severe sepsis mortality, we develop methods to address two common problems in observational studies: (1) when there is a lack of…

Applications · Statistics 2015-08-13 Colin B. Fogarty , Mark E. Mikkelsen , David F. Gaieski , Dylan S. Small