Related papers: Free boundary limits of coupled bulk-surface model…
We consider a coupled bulk-surface system of partial differential equations with nonlinear coupling modelling receptor-ligand dynamics. The model arises as a simplification of a mathematical model for the reaction between cell surface…
We prove existence, uniqueness, and regularity for a reaction-diffusion system of coupled bulk-surface equations on a moving domain modelling receptor-ligand dynamics in cells. The nonlinear coupling between the three unknowns is through…
The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model…
We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. The authors have justified the well-posedness of this problem and have…
In this article we formulate new models for coupled systems of bulk-surface reaction-diffusion equations on stationary volumes. The bulk reaction-diffusion equations are coupled to the surface reaction-diffusion equations through linear…
Bulk-surface systems on evolving domains are studied. Such problems appear typically from modelling receptor-ligand dynamics in biological cells. Our first main result is the global existence and boundedness of solutions in all dimensions.…
In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…
We introduce and analyze a nonlocal version of the one-phase Stefan problem in which, as in the classical model, the rate of growth of the volume of the liquid phase is proportional to the rate at which energy is lost through the…
A horizontal $N$-dimensional plane, having a diffusion of its own, exchanges with the lower half space. There, a reaction-diffusion process, modelled by a free boundary problem, takes place. We wish to understand whether, and how, the free…
We derive a thermodynamically consistent model, which describes the time evolution of a two-phase flow in an evolving domain. The movement of the free boundary of the domain is driven by the velocity field of the mixture in the bulk, which…
We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. In previous papers, we have established well-posedness of this problem and…
In this paper we numerically research the solutions of the phase field system for the spherically symmetric Stefan-Gibbs-Thomson problem in the case of interaction of the free boundaries. We analyze the effect of the soliton type…
At the continuous level, we consider two types of tumor growth models: the cell density model, which is based on the fluid mechanical construction, is more favorable for scientific interpretation and numerical simulations; and the free…
In this volume a theory for models of transport in the presence of a free boundary is developed. Macroscopic laws of transport are described by PDEs. When the system is open, there are several mechanisms to couple the system with the…
The current series of research papers is to investigate the asymptotic dynamics in logistic type chemotaxis models in one space dimension with a free boundary or an unbounded boundary. Such a model with a free boundary describes the…
A mutualist model with nonlocal diffusions and a free boundary is first considered. We prove that this problem has a unique solution defined $t\ge0$, and its dynamics are governed by a spreading-vanishing dichotomy. Some criteria for…
The current series of research papers is to investigate the asymptotic dynamics in logistic type chemotaxis models in one space dimension with a free boundary or unbounded boundary. Such a model with a free boundary describes the spreading…
We report on recent progress in the study of evolution processes involving degenerate parabolic equations what may exhibit free boundaries. The equations we have selected follow to recent trends in diffusion theory: considering anomalous…
In this paper we study a free boundary problem for the growth of multi-layer tumors in necrotic phase. The tumor region is strip-like and divided into necrotic region and proliferating region with two free boundaries. The upper free…
Realistic examples of reaction-diffusion phenomena governing spatial and spatiotemporal pattern formation are rarely isolated systems, either chemically or thermodynamically. However, even formulations of `open' reaction-diffusion systems…