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The adoption of neural network models in medical imaging has been constrained by strict privacy regulations, limited data availability, high acquisition costs, and demographic biases. Deep generative models offer a promising solution by…

Image and Video Processing · Electrical Eng. & Systems 2025-06-16 Zuzanna Skorniewska , Bartlomiej W. Papiez

Differentially private learning on real-world data poses challenges for standard machine learning practice: privacy guarantees are difficult to interpret, hyperparameter tuning on private data reduces the privacy budget, and ad-hoc privacy…

Machine Learning · Statistics 2018-12-10 Koen Lennart van der Veen , Ruben Seggers , Peter Bloem , Giorgio Patrini

Many approaches have been proposed to use diffusion models to augment training datasets for downstream tasks, such as classification. However, diffusion models are themselves trained on large datasets, often with noisy annotations, and it…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Max F. Burg , Florian Wenzel , Dominik Zietlow , Max Horn , Osama Makansi , Francesco Locatello , Chris Russell

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Despite recent progress in enhancing the privacy of federated learning (FL) via differential privacy (DP), the trade-off of DP between privacy protection and performance is still underexplored for real-world medical scenario. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Meirui Jiang , Yuan Zhong , Anjie Le , Xiaoxiao Li , Qi Dou

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

Deep learning models in medical contexts face challenges like data scarcity, inhomogeneity, and privacy concerns. This study focuses on improving ventricular segmentation in brain MRI images using synthetic data. We employed two latent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Tim Ruschke , Jonathan Frederik Carlsen , Adam Espe Hansen , Ulrich Lindberg , Amalie Monberg Hindsholm , Martin Norgaard , Claes Nøhr Ladefoged

Achieving robust performance and fairness across diverse patient populations remains a challenge in developing clinically deployable deep learning models for diagnostic imaging. Synthetic data generation has emerged as a promising strategy…

Synthetic data has recently reached a level of visual fidelity that makes it nearly indistinguishable from real data, offering great promise for privacy-preserving data sharing in medical imaging. However, fully synthetic datasets still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Mischa Dombrowski , Bernhard Kainz

With increasing concerns over privacy in healthcare, especially for sensitive medical data, this research introduces a federated learning framework that combines local differential privacy and secure aggregation using Secure Multi-Party…

Machine Learning · Computer Science 2024-12-03 Mohamad Haj Fares , Ahmed Mohamed Saad Emam Saad

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

Cryptography and Security · Computer Science 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

Synthetic data from generative models emerges as the privacy-preserving data sharing solution. Such a synthetic data set shall resemble the original data without revealing identifiable private information. Till date, the prior focus on…

Machine Learning · Computer Science 2025-07-23 Chaoyi Zhu , Jiayi Tang , Juan F. Pérez , Marten van Dijk , Lydia Y. Chen

While deep learning holds great promise for disease diagnosis and prognosis in cardiac magnetic resonance imaging, its progress is often constrained by highly imbalanced and biased training datasets. To address this issue, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Grzegorz Skorupko , Richard Osuala , Zuzanna Szafranowska , Kaisar Kushibar , Vien Ngoc Dang , Nay Aung , Steffen E Petersen , Karim Lekadir , Polyxeni Gkontra

Diffusion models are becoming defector generative models, which generate exceptionally high-resolution image data. Training effective diffusion models require massive real data, which is privately owned by distributed parties. Each data…

Artificial Intelligence · Computer Science 2024-06-03 Jiyue Huang , Chi Hong , Lydia Y. Chen , Stefanie Roos

Recent years have witnessed the tremendous success of diffusion models in data synthesis. However, when diffusion models are applied to sensitive data, they also give rise to severe privacy concerns. In this paper, we systematically present…

Cryptography and Security · Computer Science 2023-01-25 Hailong Hu , Jun Pang

In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality…

Medical image annotation is constrained by privacy concerns and labor-intensive labeling, significantly limiting the performance and generalization of segmentation models. While mask-controllable diffusion models excel in synthesis, they…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Kunpeng Qiu , Zhiying Zhou , Yongxin Guo

In privacy-preserving machine learning, differentially private stochastic gradient descent (DP-SGD) performs worse than SGD due to per-sample gradient clipping and noise addition. A recent focus in private learning research is improving the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Xinyu Tang , Ashwinee Panda , Vikash Sehwag , Prateek Mittal

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai
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