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IMPORTANCE The response effectiveness of different large language models (LLMs) and various individuals, including medical students, graduate students, and practicing physicians, in pediatric ophthalmology consultations, has not been…

Lab results are often confusing and hard to understand. Large language models (LLMs) such as ChatGPT have opened a promising avenue for patients to get their questions answered. We aim to assess the feasibility of using LLMs to generate…

Purpose: Enhanced health literacy has been linked to better health outcomes; however, few interventions have been studied. We investigate whether large language models (LLMs) can serve as a medium to improve health literacy in children and…

Since the release of ChatGPT in November 2022, large language models (LLMs) have seen considerable success, including in the open-source community, with many open-weight models available. However, the requirements to deploy such a service…

Background Large language models (LLMs) are increasingly deployed in medical consultations, yet their safety under realistic user pressures remains understudied. Prior assessments focused on neutral conditions, overlooking vulnerabilities…

As Large Language Models (LLMs) are predictive models building their response based on the words in the prompts, there is a risk that small talk and irrelevant information may alter the response and the suggestion given. Therefore, this…

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

This paper investigates the performance of the Large Language Models (LLMs) ChatGPT-3.5 and GPT-4 in solving introductory programming tasks. Based on the performance, implications for didactic scenarios and assessment formats utilizing LLMs…

Large Language Models (LLMs) have emerged as a potential solution to assist digital health development with patient education, commonly medication-related enquires. We trained and validated Med-Pal, a medication domain-specific LLM-chatbot…

Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

This paper presents a comprehensive survey of ChatGPT-related (GPT-3.5 and GPT-4) research, state-of-the-art large language models (LLM) from the GPT series, and their prospective applications across diverse domains. Indeed, key innovations…

Millions of patients are already using large language model (LLM) chatbots for medical advice on a regular basis, raising patient safety concerns. This physician-led red-teaming study compares the safety of four publicly available…

Large language models (LLMs) such as ChatGPT and Vicuna have shown remarkable capacities in comprehending and producing language. However, their internal workings remain a black box, and it is unclear whether LLMs and chatbots can develop…

Recently developed large language models (LLMs) such as ChatGPT, Claude, and Llama have demonstrated impressive abilities, and even surpass human-level performance in several tasks. Despite their success, the resource-intensive demands of…

Open-weight versions of large language models (LLMs) are rapidly advancing, with state-of-the-art models like DeepSeek-V3 now performing comparably to proprietary LLMs. This progression raises the question of whether small open-weight LLMs…

This study evaluates the performance of several Large Language Models (LLMs) on MedRedQA, a dataset of consumer-based medical questions and answers by verified experts extracted from the AskDocs subreddit. While LLMs have shown proficiency…

Large Language Models (LLMs) are distinguished by their architecture, which dictates their parameter size and performance capabilities. Social scientists have increasingly adopted LLMs for text classification tasks, which are difficult to…

Recently, Large Language Models (LLMs) have gained significant traction in medical domain, especially in developing a QA systems to Medical QA systems for enhancing access to healthcare in low-resourced settings. This paper compares five…