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Among the plethora of techniques devised to curb the prevalence of noise in medical images, deep learning based approaches have shown the most promise. However, one critical limitation of these deep learning based denoisers is the…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Fahad Shamshad , Muhammad Awais , Muhammad Asim , Zain ul Aabidin Lodhi , Muhammad Umair , Ali Ahmed

Recently, Stein's unbiased risk estimator (SURE) has been applied to unsupervised training of deep neural network Gaussian denoisers that outperformed classical non-deep learning based denoisers and yielded comparable performance to those…

Computer Vision and Pattern Recognition · Computer Science 2019-09-09 Magauiya Zhussip , Shakarim Soltanayev , Se Young Chun

Learning from unlabeled and noisy data is one of the grand challenges of machine learning. As such, it has seen a flurry of research with new ideas proposed continuously. In this work, we revisit a classical idea: Stein's Unbiased Risk…

Machine Learning · Statistics 2020-07-24 Christopher A. Metzler , Ali Mousavi , Reinhard Heckel , Richard G. Baraniuk

Recently developed deep-learning-based denoisers often outperform state-of-the-art conventional denoisers such as the BM3D. They are typically trained to minimize the mean squared error (MSE) between the output image of a deep neural…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Shakarim Soltanayev , Se Young Chun

Image reconstruction using deep learning algorithms offers improved reconstruction quality and lower reconstruction time than classical compressed sensing and model-based algorithms. Unfortunately, clean and fully sampled ground-truth data…

Computer Vision and Pattern Recognition · Computer Science 2022-12-05 Hemant Kumar Aggarwal , Aniket Pramanik , Maneesh John , Mathews Jacob

Recently, many self-supervised learning methods for image reconstruction have been proposed that can learn from noisy data alone, bypassing the need for ground-truth references. Most existing methods cluster around two classes: i) Stein's…

Machine Learning · Statistics 2025-02-12 Julián Tachella , Mike Davies , Laurent Jacques

Deep learning algorithms that rely on extensive training data are revolutionizing image recovery from ill-posed measurements. Training data is scarce in many imaging applications, including ultra-high-resolution imaging. The deep image…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Maneesh John , Hemant Kumar Aggarwal , Qing Zou , Mathews Jacob

Unsupervised denoising is a crucial challenge in real-world imaging applications. Unsupervised deep-learning methods have demonstrated impressive performance on benchmarks based on synthetic noise. However, no metrics are available to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Adria Marcos-Morales , Matan Leibovich , Sreyas Mohan , Joshua Lawrence Vincent , Piyush Haluai , Mai Tan , Peter Crozier , Carlos Fernandez-Granda

Magnetic Resonance Imaging (MRI) is an essential diagnostic tool in clinical settings but its utility is often hindered by noise artifacts introduced during the imaging process. Effective denoising is critical for enhancing image quality…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Zeyun Deng , Joseph Campbell

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

Deep learning image reconstruction algorithms often suffer from model mismatches when the acquisition scheme differs significantly from the forward model used during training. We introduce a Generalized Stein's Unbiased Risk Estimate…

Machine Learning · Computer Science 2022-01-02 Hemant Kumar Aggarwal , Mathews Jacob

Ultrasound images are widespread in medical diagnosis for muscle-skeletal, cardiac, and obstetrical diseases, due to the efficiency and non-invasiveness of the acquisition methodology. However, ultrasound acquisition introduces noise in the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Simone Cammarasana , Paolo Nicolardi , Giuseppe Patanè

Ultrasound images are widespread in medical diagnosis for musculoskeletal, cardiac, and obstetrical imaging due to the efficiency and non-invasiveness of the acquisition methodology. However, the acquired images are degraded by acoustic…

Image and Video Processing · Electrical Eng. & Systems 2023-06-14 Hojat Asgariandehkordi , Sobhan Goudarzi , Adrian Basarab , Hassan Rivaz

Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Hyungjin Chung , Eun Sun Lee , Jong Chul Ye

We consider the problem of estimating a low-rank signal matrix from noisy measurements under the assumption that the distribution of the data matrix belongs to an exponential family. In this setting, we derive generalized Stein's unbiased…

Statistics Theory · Mathematics 2017-10-03 Jérémie Bigot , Charles Deledalle , Delphine Féral

In the era of Foundation Models' (FMs) rising prominence in AI, our study addresses the challenge of biases in medical images while the model operates in black-box (e.g., using FM API), particularly spurious correlations between pixels and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Ruinan Jin , Wenlong Deng , Minghui Chen , Xiaoxiao Li

Convolutional neural networks (CNN) have emerged as a powerful tool for solving computational imaging reconstruction problems. However, CNNs are generally difficult-to-understand black-boxes. Accordingly, it is challenging to know when they…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Ruangrawee Kitichotkul , Christopher A. Metzler , Frank Ong , Gordon Wetzstein

We address the problem of image denoising in additive white noise without placing restrictive assumptions on its statistical distribution. In the recent literature, specific noise distributions have been considered and correspondingly,…

Computer Vision and Pattern Recognition · Computer Science 2015-01-28 Sagar Venkatesh Gubbi , Chandra Sekhar Seelamantula

Stein's unbiased risk estimate (SURE) was proposed by Stein for the independent, identically distributed (iid) Gaussian model in order to derive estimates that dominate least-squares (LS). In recent years, the SURE criterion has been…

Methodology · Statistics 2009-11-13 Yonina C. Eldar

This paper revisits two prominent adaptive filtering algorithms, namely recursive least squares (RLS) and equivariant adaptive source separation (EASI), through the lens of algorithm unrolling. Building upon the unrolling methodology, we…

Signal Processing · Electrical Eng. & Systems 2023-11-17 Zahra Esmaeilbeig , Mojtaba Soltanalian
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