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Survival random forest is a popular machine learning tool for modeling censored survival data. However, there is currently no statistically valid and computationally feasible approach for estimating its confidence band. This paper proposes…

Methodology · Statistics 2022-04-27 Sarah Elizabeth Formentini , Wei Liang , Ruoqing Zhu

Objectives: Lung cancer poses a significant global health challenge, necessitating improved prognostic methods for personalized treatment. This study introduces a censor-aware semi-supervised learning (SSL) framework that integrates…

Medical Physics · Physics 2025-06-16 Arman Gorji , Ali Fathi Jouzdani , Nima Sanati , Ren Yuan , Arman Rahmim , Mohammad R. Salmanpour

Survival analysis is a fundamental area of focus in biomedical research, particularly in the context of personalized medicine. This prominence is due to the increasing prevalence of large and high-dimensional datasets, such as omics and…

Machine Learning · Statistics 2024-08-23 Carlos García Meixide , Marcos Matabuena , Louis Abraham , Michael R. Kosorok

Random Forest (RF) is a well-known data-driven algorithm applied in several fields thanks to its flexibility in modeling the relationship between the response variable and the predictors, also in case of strong non-linearities. In…

Machine Learning · Statistics 2023-10-18 Luca Patelli , Michela Cameletti , Natalia Golini , Rosaria Ignaccolo

This paper addresses the problem of identifying and estimating the causal effect of a treatment in the presence of unmeasured confounding and various types of right-censoring. Examples of these censoring mechanisms are administrative…

Statistics Theory · Mathematics 2025-03-19 Ilias Willems , Sara Rutten , Gilles Crommen , Ingrid Van Keilegom

Residuals in normal regression are used to assess a model's goodness-of-fit (GOF) and discover directions for improving the model. However, there is a lack of residuals with a characterized reference distribution for censored regression. In…

Methodology · Statistics 2022-01-04 Longhai Li , Tingxuan Wu , Cindy Feng

Survival analysis, time-to-event analysis, is an important problem in healthcare since it has a wide-ranging impact on patients and palliative care. Many survival analysis methods have assumed that the survival data is centrally available…

Machine Learning · Computer Science 2022-07-13 Md Mahmudur Rahman , Sanjay Purushotham

Ranked set sampling (RSS) is a cost-efficient study design that uses inexpensive baseline ranking to select a more informative subset of individuals for full measurement. While RSS is well known to improve precision over simple random…

Methodology · Statistics 2025-12-30 Nabil Awan , Richard J. Chappell

Privacy and regulatory barriers often hinder centralized machine learning solutions, particularly in sectors like healthcare where data cannot be freely shared. Federated learning has emerged as a powerful paradigm to address these…

Machine Learning · Computer Science 2025-07-23 Alexandre Cotorobai , Jorge Miguel Silva , Jose Luis Oliveira

Applications of machine learning in healthcare often require working with time-to-event prediction tasks including prognostication of an adverse event, re-hospitalization or death. Such outcomes are typically subject to censoring due to…

Machine Learning · Computer Science 2022-08-04 Chirag Nagpal , Willa Potosnak , Artur Dubrawski

Functional Isolation Forest (FIF) is a recent state-of-the-art Anomaly Detection (AD) algorithm designed for functional data. It relies on a tree partition procedure where an abnormality score is computed by projecting each curve…

Machine Learning · Statistics 2025-02-26 Marta Campi , Guillaume Staerman , Gareth W. Peters , Tomoko Matsui

In survival analysis, estimating the conditional survival function given predictors is often of interest. There is a growing trend in the development of deep learning methods for analyzing censored time-to-event data, especially when…

Machine Learning · Statistics 2025-03-13 Sehwan Kim , Rui Wang , Wenbin Lu

Functional data analysis (FDA) and ensemble learning can be powerful tools for analyzing complex environmental time series. Recent literature has highlighted the key role of diversity in enhancing accuracy and reducing variance in ensemble…

Machine Learning · Statistics 2024-09-13 Donato Riccio , Fabrizio Maturo , Elvira Romano

We introduce a modification of Random Forests to estimate functions when unobserved confounding variables are present. The technique is tailored for high-dimensional settings with many observed covariates. We use spectral deconfounding…

Computation · Statistics 2025-09-25 Markus Ulmer , Cyrill Scheidegger , Peter Bühlmann

The restricted mean survival time (RMST) has become a popular measure to summarize event times in longitudinal studies. Defined as the area under the survival function up to a time horizon $\tau$ > 0, the RMST can be interpreted as the life…

Methodology · Statistics 2024-11-05 Alina Schenk , Vanessa Basten , Matthias Schmid

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

Methodology · Statistics 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

The wealth of data being gathered about humans and their surroundings drives new machine learning applications in various fields. Consequently, more and more often, classifiers are trained using not only numerical data but also complex data…

Machine Learning · Computer Science 2022-04-13 Maciej Piernik , Dariusz Brzezinski , Pawel Zawadzki

Factorial analyses offer a powerful nonparametric means to detect main or interaction effects among multiple treatments. For survival outcomes, e.g. from clinical trials, such techniques can be adopted for comparing reasonable…

Methodology · Statistics 2023-02-06 Takeshi Emura , Marc Ditzhaus , Dennis Dobler , Kenta Murotani

Survival analysis provides a powerful statistical framework for modeling time-to-event outcomes in the presence of censoring. However, selecting an appropriate estimator from the many specialized survival approaches often requires…

Machine Learning · Computer Science 2026-05-18 Shi-ang Qi , Vahid Balazadeh , Michael Cooper , Russell Greiner , Rahul G. Krishnan

In modern scientific research, the objective is often to identify which variables are associated with an outcome among a large class of potential predictors. This goal can be achieved by selecting variables in a manner that controls the the…

Methodology · Statistics 2023-10-10 Yushu Shi , Michael Martens