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Recent studies have demonstrated that In-Context Learning (ICL), through the use of specific demonstrations, can align Large Language Models (LLMs) with human preferences known as In-Context Alignment (ICA), indicating that models can…

Computation and Language · Computer Science 2024-06-18 Heyan Huang , Yinghao Li , Huashan Sun , Yu Bai , Yang Gao

Retrieval Augmented Generation (RAG) systems have emerged as a powerful method for enhancing large language models (LLMs) with up-to-date information. However, the retrieval step in RAG can sometimes surface documents containing…

Computation and Language · Computer Science 2025-04-02 Vignesh Gokul , Srikanth Tenneti , Alwarappan Nakkiran

Recently, the astonishing performance of large language models (LLMs) in natural language comprehension and generation tasks triggered lots of exploration of using them as central controllers to build agent systems. Multiple studies focus…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Chenyu Wang , Weixin Luo , Sixun Dong , Xiaohua Xuan , Zhengxin Li , Lin Ma , Shenghua Gao

The effectiveness of Large Language Models (LLMs) in generating accurate responses relies heavily on the quality of input provided, particularly when employing Retrieval Augmented Generation (RAG) techniques. RAG enhances LLMs by sourcing…

Information Retrieval · Computer Science 2024-08-02 Spurthi Setty , Harsh Thakkar , Alyssa Lee , Eden Chung , Natan Vidra

Recent advances in large language models (LLMs) have shown great potential to accelerate drug discovery. However, the specialized nature of biochemical data often necessitates costly domain-specific fine-tuning, posing major challenges.…

Machine Learning · Computer Science 2025-11-17 Namkyeong Lee , Edward De Brouwer , Ehsan Hajiramezanali , Tommaso Biancalani , Chanyoung Park , Gabriele Scalia

Large Language Models (LLMs) have garnered significant attention due to their remarkable ability to process information across various languages. Despite their capabilities, they exhibit inconsistencies in handling identical queries in…

Computation and Language · Computer Science 2024-06-24 Yue Huang , Chenrui Fan , Yuan Li , Siyuan Wu , Tianyi Zhou , Xiangliang Zhang , Lichao Sun

Chatbots via large language models (LLMs) generate fluent responses but often struggle with when to speak, especially for brief, timely listener reactions during ongoing dialogue. We present a multimodal strategy for LLMs, which leverages…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Zikai Liao , Yi Ouyang , Yi-Lun Lee , Chen-Ping Yu , Yi-Hsuan Tsai , Zhaozheng Yin

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large Language Models (LLMs) have significantly advanced natural language processing, demonstrating exceptional reasoning, tool usage, and memory capabilities. As their applications expand into multi-agent environments, there arises a need…

Computation and Language · Computer Science 2024-11-28 Lin Xu , Zhiyuan Hu , Daquan Zhou , Hongyu Ren , Zhen Dong , Kurt Keutzer , See Kiong Ng , Jiashi Feng

Recent advancements in Large Language Models (LLMs) have yielded remarkable success across diverse fields. However, handling long contexts remains a significant challenge for LLMs due to the quadratic time and space complexity of attention…

Computation and Language · Computer Science 2024-09-02 Weijie Liu , Zecheng Tang , Juntao Li , Kehai Chen , Min Zhang

In-Context Learning (ICL) enables transformer-based language models to adapt to new tasks by conditioning on demonstration examples. However, traditional example-driven in-context learning lacks explicit modules for knowledge retrieval and…

Computation and Language · Computer Science 2026-03-31 Pan Chen , Shaohong Chen , Mark Wang , Shi Xuan Leong , Priscilla Fung , Varinia Bernales , Alan Aspuru-Guzik

Proprietary Large Language Models (LLMs), such as ChatGPT, have garnered significant attention due to their exceptional capabilities in handling a diverse range of tasks. Recent studies demonstrate that open-sourced smaller foundational…

Computation and Language · Computer Science 2023-10-10 Yue Zhang , Leyang Cui , Deng Cai , Xinting Huang , Tao Fang , Wei Bi

Multimodal scientific reasoning remains a significant challenge for large language models (LLMs), particularly in chemistry, where problem-solving relies on symbolic diagrams, molecular structures, and structured visual data. Here, we…

Computation and Language · Computer Science 2025-12-18 Yiming Cui , Xin Yao , Yuxuan Qin , Xin Li , Shijin Wang , Guoping Hu

Medical Large Vision-Language Models (Med-LVLMs) have shown strong potential in multimodal diagnostic tasks. However, existing single-agent models struggle to generalize across diverse medical specialties, limiting their performance. Recent…

Machine Learning · Computer Science 2026-01-27 Peng Xia , Jinglu Wang , Yibo Peng , Kaide Zeng , Zihan Dong , Xian Wu , Xiangru Tang , Hongtu Zhu , Yun Li , Linjun Zhang , Shujie Liu , Yan Lu , Huaxiu Yao

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Most of the existing medication recommendation models are predicted with only structured data such as medical codes, with the remaining other large amount of unstructured or semi-structured data underutilization. To increase the utilization…

Computation and Language · Computer Science 2024-07-16 Yu-Tzu Lee

Retrieval-Augmented Generation (RAG) systems in chemistry heavily depend on accurate and relevant retrieval of chemical literature. However, general-purpose text embedding models frequently fail to adequately represent complex chemical…

Large Language Models (LLMs) demonstrate proficiency across diverse tasks but often require targeted adaptations for specific applications. Various methods have been proposed to facilitate this adaptation, including fewshot fine-tuning,…

Machine Learning · Computer Science 2025-11-10 Rajesh Upadhayaya , Manish Raj Osti , Zachary Smith , Chritopher Kottmyer

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Organic reaction mechanisms are the stepwise elementary reactions by which reactants form intermediates and products, and are fundamental to understanding chemical reactivity and designing new molecules and reactions. Although large…

Artificial Intelligence · Computer Science 2026-05-05 Ruiling Xu , Yifan Zhang , Qingyun Wang , Carl Edwards , Heng Ji
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