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Medical image segmentation is critical for diagnosing and treating spinal disorders. However, the presence of high noise, ambiguity, and uncertainty makes this task highly challenging. Factors such as unclear anatomical boundaries,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-13 Zhiqing Zhang , Guojia Fan , Tianyong Liu , Nan Li , Yuyang Liu , Ziyu Liu , Canwei Dong , Shoujun Zhou

Through Diffusion Models (DMs), we have made significant advances in generating high-quality images. Our exploration of these models delves deeply into their core operational principles by systematically investigating key aspects across…

Machine Learning · Computer Science 2024-02-22 Karam Ghanem , Danilo Bzdok

Denoising diffusion models, a class of generative models, have garnered immense interest lately in various deep-learning problems. A diffusion probabilistic model defines a forward diffusion stage where the input data is gradually perturbed…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Amirhossein Kazerouni , Ehsan Khodapanah Aghdam , Moein Heidari , Reza Azad , Mohsen Fayyaz , Ilker Hacihaliloglu , Dorit Merhof

Unsupervised anomaly detection and localization is crucial to the practical application when collecting and labeling sufficient anomaly data is infeasible. Most existing representation-based approaches extract normal image features with a…

Computer Vision and Pattern Recognition · Computer Science 2021-11-17 Jiawei Yu , Ye Zheng , Xiang Wang , Wei Li , Yushuang Wu , Rui Zhao , Liwei Wu

Due to the diversity of brain anatomy and the scarcity of annotated data, supervised anomaly detection for brain MRI remains challenging, driving the development of unsupervised anomaly detection (UAD) approaches. Current UAD methods…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Hao Li , Zhenfeng Zhuang , Jingyu Lin , Yu Liu , Yifei Chen , Qiong Peng , Lequan Yu , Liansheng Wang

Anomaly localization in images -- identifying regions that deviate from normal patterns -- is vital in applications such as medical diagnosis and industrial inspection. A recent trend is the use of image generation models in anomaly…

Machine Learning · Statistics 2026-04-28 Teruyuki Katsuoka , Tomohiro Shiraishi , Daiki Miwa , Vo Nguyen Le Duy , Ichiro Takeuchi

Contrastive Analysis (CA) detects anomalies by contrasting patterns unique to a target group (e.g., unhealthy subjects) from those in a background group (e.g., healthy subjects). In the context of brain MRIs, existing CA approaches rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Cristiano Patrício , Carlo Alberto Barbano , Attilio Fiandrotti , Riccardo Renzulli , Marco Grangetto , Luis F. Teixeira , João C. Neves

Out-of-distribution detection is crucial to the safe deployment of machine learning systems. Currently, unsupervised out-of-distribution detection is dominated by generative-based approaches that make use of estimates of the likelihood or…

Reconstruction-based methods have been commonly used for unsupervised anomaly detection, in which a normal image is reconstructed and compared with the given test image to detect and locate anomalies. Recently, diffusion models have shown…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Di Wu , Shicai Fan , Xue Zhou , Li Yu , Yuzhong Deng , Jianxiao Zou , Baihong Lin

Ultrasound offers a safe, cost-effective, and widely accessible technology for fetal brain imaging, making it especially suitable for routine clinical use. However, it suffers from view-dependent artifacts, operator variability, and a…

Image and Video Processing · Electrical Eng. & Systems 2026-01-13 Mohammad Khateri , Morteza Ghahremani , Sergio Valencia , Camilo Jaimes , Alejandra Sierra , Jussi Tohka , P. Ellen Grant , Davood Karimi

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Unsupervised anomaly detection (UAD) in medical imaging is crucial for identifying pathological abnormalities without requiring extensive labeled data. However, existing diffusion-based UAD models rely solely on imaging features, limiting…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Harim Kim , Yuhan Wang , Minkyu Ahn , Heeyoul Choi , Yuyin Zhou , Charmgil Hong

Detecting out-of-distribution (OOD) inputs is pivotal for deploying safe vision systems in open-world environments. We revisit diffusion models, not as generators, but as universal perceptual templates for OOD detection. This research…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Lemar Abdi , Amaan Valiuddin , Francisco Caetano , Christiaan Viviers , Fons van der Sommen

In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Zhaohu Xing , Liang Wan , Huazhu Fu , Guang Yang , Lei Zhu

Ultrasound imaging is widely used in medical diagnosis, especially for fetal health assessment. However, the availability of high-quality annotated ultrasound images is limited, which restricts the training of machine learning models. In…

Computer Vision and Pattern Recognition · Computer Science 2025-07-04 Yueying Tian , Elif Ucurum , Xudong Han , Rupert Young , Chris Chatwin , Philip Birch

This paper investigates the performance of diffusion models for video anomaly detection (VAD) within the most challenging but also the most operational scenario in which the data annotations are not used. As being sparse, diverse,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Anil Osman Tur , Nicola Dall'Asen , Cigdem Beyan , Elisa Ricci

Diffusion probabilistic models (DPMs) have exhibited significant effectiveness in computer vision tasks, particularly in image generation. However, their notable performance heavily relies on labelled datasets, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Keqiang Fan , Xiaohao Cai , Mahesan Niranjan

Latent defect screening is challenged by extremely low failure rates, high-dimensional test data, and absence of labeled anomalies. We propose the first unsupervised anomaly detection framework incorporating a Diffusion Transformer. Raw…

Machine Learning · Computer Science 2026-05-27 Yuxuan Yin , Chen He , Todd Jacobs , Jialei He , Boxun Xu , Robert Jin , Peng Li

Unsupervised Anomaly Detection has become a popular method to detect pathologies in medical images as it does not require supervision or labels for training. Most commonly, the anomaly detection model generates a "normal" version of an…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Felix Meissen , Johannes Paetzold , Georgios Kaissis , Daniel Rueckert

Due to the high complexity and technical requirements of industrial production processes, surface defects will inevitably appear, which seriously affects the quality of products. Although existing lightweight detection networks are highly…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Xuyi Yu