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The rapid digitization of histopathology slides has opened up new possibilities for computational tools in clinical and research workflows. Among these, content-based slide retrieval stands out, enabling pathologists to identify…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hongyi Wang , Zhengjie Zhu , Jiabo Ma , Fang Wang , Yue Shi , Bo Luo , Jili Wang , Qiuyu Cai , Xiuming Zhang , Yen-Wei Chen , Lanfen Lin , Hao Chen

The fusion of language and vision in large vision-language models (LVLMs) has revolutionized deep learning-based object detection by enhancing adaptability, contextual reasoning, and generalization beyond traditional architectures. This…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Ranjan Sapkota , Manoj Karkee

Incorporating multiple modalities into large language models (LLMs) is a powerful way to enhance their understanding of non-textual data, enabling them to perform multimodal tasks. Vision language models (VLMs) form the fastest growing…

Machine Learning · Computer Science 2025-02-04 Shiqi He , Insu Jang , Mosharaf Chowdhury

Modern Vision-Language Models (VLMs) exhibit unprecedented capabilities in cross-modal semantic understanding between visual and textual modalities. Given the intrinsic need for multi-modal integration in clinical applications, VLMs have…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 Haoneng Lin , Cheng Xu , Jing Qin

The integration of artificial intelligence (AI) with radiology marks a transformative era in medicine. Vision foundation models have been adopted to enhance radiologic imaging analysis. However, the distinct complexities of radiologic 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Zhixiu Lu , Hailong Li , Nehal A. Parikh , Jonathan R. Dillman , Lili He

Remarkable progress has been made by data-driven machine-learning methods in the analysis of MRI scans. However, most existing MRI analysis approaches are crafted for specific MR pulse sequences (MR contrasts) and usually require nearly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Peirong Liu , Oula Puonti , Annabel Sorby-Adams , William T. Kimberly , Juan E. Iglesias

Low back pain affects millions worldwide, driving the need for robust diagnostic models that can jointly analyze complex medical images and accompanying text reports. We present LumbarCLIP, a novel multimodal framework that leverages…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Thanh Binh Le , Hoang Nhat Khang Vo , Tan-Ha Mai , Trong Nhan Phan

Large-scale pre-trained Vision-Language Models (VLMs), such as CLIP, establish the correlation between texts and images, achieving remarkable success on various downstream tasks with fine-tuning. In existing fine-tuning methods, the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Yi Zhang , Ce Zhang , Yushun Tang , Zhihai He

Despite the promise of foundation models in medical AI, current systems remain limited - they are modality-specific and lack transparent reasoning processes, hindering clinical adoption. To address this gap, we present EVLF-FM, a multimodal…

In high-stakes medical applications, consistent answering across diverse question phrasings is essential for reliable diagnosis. However, we reveal that current Medical Vision-Language Models (Med-VLMs) exhibit concerning fragility in…

Computation and Language · Computer Science 2025-08-27 Songtao Jiang , Yuxi Chen , Sibo Song , Yan Zhang , Yeying Jin , Yang Feng , Jian Wu , Zuozhu Liu

Whole slide images (WSIs) in computational pathology (CPath) pose a major computational challenge due to their gigapixel scale, often requiring the processing of tens to hundreds of thousands of high-resolution patches per slide. This…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Yonghan Shin , SeungKyu Kim , Won-Ki Jeong

Surgery is a highly complex process, and artificial intelligence has emerged as a transformative force in supporting surgical guidance and decision-making. However, the unimodal nature of most current AI systems limits their ability to…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Nakul Poudel , Richard Simon , Cristian A. Linte

Medical image segmentation is a fundamental yet challenging task due to the arduous process of acquiring large volumes of high-quality labeled data from experts. Contrastive learning offers a promising but still problematic solution to this…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Shuang Zeng , Lei Zhu , Xinliang Zhang , Micky C Nnamdi , Wenqi Shi , J Ben Tamo , Qian Chen , Hangzhou He , Lujia Jin , Zifeng Tian , Qiushi Ren , Zhaoheng Xie , Yanye Lu

Pathological diagnosis remains the definitive standard for identifying tumors. The rise of multimodal large models has simplified the process of integrating image analysis with textual descriptions. Despite this advancement, the substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Xiaomin Wu , Rui Xu , Pengchen Wei , Wenkang Qin , Peixiang Huang , Ziheng Li , Lin Luo

Vision language models (VLM) have achieved success in both natural language comprehension and image recognition tasks. However, their use in pathology report generation for whole slide images (WSIs) is still limited due to the huge size of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Jing Wei Tan , SeungKyu Kim , Eunsu Kim , Sung Hak Lee , Sangjeong Ahn , Won-Ki Jeong

Recent advances in vision language models (VLMs) have enabled broad progress in the general medical field. However, pathology still remains a more challenging subdomain, with current pathology specific VLMs exhibiting limitations in both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Penghao Zhang , Jingru Guo , Tao Cheng , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Survival prediction using whole-slide images (WSIs) is crucial in cancer re-search. Despite notable success, existing approaches are limited by their reliance on sparse slide-level labels, which hinders the learning of discriminative…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Jiaqi Cui , Lu Wen , Yuchen Fei , Bo Liu , Luping Zhou , Dinggang Shen , Yan Wang

Vision-Language Models (VLMs) have shown impressive performance in vision tasks, but adapting them to new domains often requires expensive fine-tuning. Prompt tuning techniques, including textual, visual, and multimodal prompting, offer…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Rabin Adhikari , Safal Thapaliya , Manish Dhakal , Bishesh Khanal

Traditional whole slide image (WSI) analysis methods typically rely on the multiple instance learning (MIL) paradigm, which extracts patch-level features at high magnification and aggregates them for slide-level prediction. However, such…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Jiusong Ge , Yingkang Zhan , Wenjie Zhao , Di Zhang , Ke Wang , Jiashuai Liu , Chunze Yang , Chengzu Li , Jian Zhang , Yuxin Dong , Ni Zhang , Qidong Liu , Mireia Crispin-Ortuzar , Huazhu Fu , Chen Li , Zeyu Gao

Recent advances in multimodal large language models (LLMs) have highlighted their potential for medical and surgical applications. However, existing surgical datasets predominantly adopt a Visual Question Answering (VQA) format with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Tae-Min Choi , Tae Kyeong Jeong , Garam Kim , Jaemin Lee , Yeongyoon Koh , In Cheul Choi , Jae-Ho Chung , Jong Woong Park , Juyoun Park