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We present SoftSMPL, a learning-based method to model realistic soft-tissue dynamics as a function of body shape and motion. Datasets to learn such task are scarce and expensive to generate, which makes training models prone to overfitting.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Igor Santesteban , Elena Garces , Miguel A. Otaduy , Dan Casas

Morphoelasticity represents a foundational theory for tracing back growth, remodelling, and morphogenesis, yet crucial challenges persist. A unified growth law -- independent of a priori assumptions about constitutive relations or specified…

Soft Condensed Matter · Physics 2025-07-29 Angelo Rosario Carotenuto , Stefania Palumbo , Arsenio Cutolo , Massimiliano Fraldi

We propose a mathematical model that combines elastic, viscous and porous effects with growth or shrinkage due to microstructural changes. This phenomenon is important in tissue or tumor growth, as well as in dermal contraction. Although…

Numerical Analysis · Mathematics 2025-12-12 Sabia Asghar , Duncan den Bakker , Etelvina Javierre , Qiyao Peng , Fred J. Vermolen

Macroscopic elastic core-shell systems can be generated as toy models to be deformed and haptically studied by hand. On the mesoscale, colloidal core-shell particles and microgels are fabricated and investigated by different types of…

Soft Condensed Matter · Physics 2022-05-30 Jannis Kolker , Lukas Fischer , Andreas M. Menzel , Hartmut Löwen

Mechanical models of tumor growth based on a porous medium approach have been attracting a lot of interest both analytically and numerically. In this paper, we study the stability properties of a finite difference scheme for a model where…

Numerical Analysis · Mathematics 2021-05-24 Noemi David , Xinran Ruan

A multiscale asymptotic homogenization method for periodic microstructured materials in presence of thermoelasticity with periodic spatially dependent one relaxation time is introduced. The asymptotic expansions of the micro-displacement…

Materials Science · Physics 2021-04-12 Deison Préve , Andrea Bacigalupo , Marco Paggi

In silico, cell based approaches for modeling biological morphogenesis are used to test and validate our understanding of the biological and mechanical process that are at work during the growth and the organization of multi-cell tissues.…

Biological Physics · Physics 2026-01-06 Raphaël Conradin , Christophe Coreixas , Jonas Latt , Bastien Chopard

Biomembranes play a central role in various phenomena like locomotion of cells, cell-cell interactions, packaging of nutrients, and in maintaining organelle morphology and functionality. During these processes, the membranes undergo…

Quantitative Methods · Quantitative Biology 2021-12-01 Debabrata Auddya , Xiaoxuan Zhang , Rahul Gulati , Ritvik Vasan , Krishna Garikipati , Padmini Rangamani , Shiva Rudraraju

Spatially confined rigid membranes reorganize their morphology in response to the imposed constraints. A crumpled elastic sheet presents a complex pattern of random folds focusing the deformation energy while compressing a membrane resting…

Modeling the spontaneous evolution of morphology in natural systems and its preservation by proportionate growth remains a major scientific challenge. Yet, it is conceivable that if the basic mechanisms of growth and the coupled kinetic…

Soft Condensed Matter · Physics 2020-12-30 Virginia von Streng , Rami Abi-Akl , Bianca Giovanardi , Tal Cohen

We introduce two 2D mechanical models reproducing the evolution of two viscous tissues in contact. Their main property is to model the swirling cell motions while keeping the tissues segregated, as observed during vertebrate embryo…

Analysis of PDEs · Mathematics 2022-03-25 Pierre Degond , Sophie Hecht , Michèle Romanos , Ariane Trescases

Mathematical models of biological populations commonly use discrete structure classes to capture trait variation among individuals (e.g. age, size, phenotype, intracellular state). Upscaling these discrete models into continuum descriptions…

Populations and Evolution · Quantitative Biology 2026-03-18 Eleonora Agostinelli , Keith L. Chambers , Helen M. Byrne , Mohit P. Dalwadi

We propose a general method for deriving one-dimensional models for nonlinear structures. It captures the contribution to the strain energy arising not only from the macroscopic elastic strain as in classical structural models, but also…

Applied Physics · Physics 2020-03-18 Claire Lestringant , Basile Audoly

Numerical dynamo models always employ parameter values that differ by orders of magnitude from the values expected in natural objects. However, such models have been successful in qualitatively reproducing properties of planetary and…

Solar and Stellar Astrophysics · Physics 2015-06-15 Rakesh K. Yadav , Thomas Gastine , Ulrich R. Christensen , Lúcia D. V. Duarte

We report on the buckling and subsequent collapse of orthotropic elastic spherical shells under volume and pressure control. Going far beyond what is known for isotropic shells, a rich morphological phase space with three distinct regimes…

Soft Condensed Matter · Physics 2019-08-02 Gautam Munglani , Falk K. Wittel , Roman Vetter , Filippo Bianchi , Hans J. Herrmann

Hard-magnetic soft materials (HMSMs) are particulate composites that consist of a soft matrix embedded with particles of high remnant magnetic induction. Since the application of an external magnetic flux induces a body couple in HMSMs, the…

Numerical Analysis · Mathematics 2023-01-05 Farzam Dadgar-Rad , Mokarram Hossain

Experiments on fracture surface morphologies offer increasing amounts of data that can be analyzed using methods of statistical physics. One finds scaling exponents associated with correlation and structure functions, indicating a rich…

Materials Science · Physics 2009-11-11 Eran Bouchbinder , Itamar Procaccia , Shani Sela

A curious feature of organ and organoid morphogenesis is that in certain cases, spatial oscillations in the thickness of the growing "film" are out-of-phase with the deformation of the slower-growing "substrate," while in other cases, the…

Biological Physics · Physics 2018-12-26 T. A. Engstrom , Teng Zhang , A. K. Lawton , A. L. Joyner , J. M. Schwarz

Flexible slender structures such as rods, ribbons, plates, and shells exhibit extreme nonlinear responses bending, twisting, buckling, wrinkling, and self contact, that defy conventional simulation frameworks. Discrete Differential Geometry…

Many parts of biological organisms are comprised of deformable porous media. The biological media is both pliable enough to deform in response to an outside force and can deform by itself using the work of an embedded muscle. For example,…

Fluid Dynamics · Physics 2021-08-18 Tagir Farkhutdinov , François Gay-Balmaz , Vakhtang Putkaradze
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