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A new ensemble framework for interpretable model called Linear Iterative Feature Embedding (LIFE) has been developed to achieve high prediction accuracy, easy interpretation and efficient computation simultaneously. The LIFE algorithm is…

Machine Learning · Statistics 2021-03-19 Agus Sudjianto , Jinwen Qiu , Miaoqi Li , Jie Chen

Explanations are crucial for building trustworthy AI systems, but a gap often exists between the explanations provided by models and those needed by users. To address this gap, we introduce MetaExplainer, a neuro-symbolic framework designed…

Human-Computer Interaction · Computer Science 2025-09-11 Shruthi Chari , Oshani Seneviratne , Prithwish Chakraborty , Pablo Meyer , Deborah L. McGuinness

Accurate prediction of synthetic lethality (SL) is important for guiding the development of cancer drugs and therapies. SL prediction faces significant challenges in the effective fusion of heterogeneous multi-source data. Existing…

The objective of this proposal is to bridge the gap between Deep Learning (DL) and System Dynamics (SD) by developing an interpretable neural system dynamics framework. While DL excels at learning complex models and making accurate…

Machine Learning · Computer Science 2025-05-21 Riccardo D'Elia

This paper investigates robot manipulation based on human instruction with ambiguous requests. The intent is to compensate for imperfect natural language via visual observations. Early symbolic methods, based on manually defined symbols,…

Robotics · Computer Science 2022-03-01 Ruinian Xu , Hongyi Chen , Yunzhi Lin , Patricio A. Vela

Synergistic drug combinations provide huge potentials to enhance therapeutic efficacy and to reduce adverse reactions. However, effective and synergistic drug combination prediction remains an open question because of the unknown causal…

Quantitative Methods · Quantitative Biology 2023-08-24 Zehao Dong , Heming Zhang , Yixin Chen , Philip R. O. Payne , Fuhai Li

Graph Neural Networks have been widely applied in critical decision-making areas that demand interpretable predictions, leading to the flourishing development of interpretability algorithms. However, current graph interpretability…

Machine Learning · Computer Science 2024-09-04 Xiaodi Li , Jianfeng Gui , Qian Gao , Haoyuan Shi , Zhenyu Yue

Advances in machine learning have led to graph neural network-based methods for drug discovery, yielding promising results in molecular design, chemical synthesis planning, and molecular property prediction. However, current graph neural…

Quantitative Methods · Quantitative Biology 2021-07-13 Jiahua Rao , Shuangjia Zheng , Yuedong Yang

Temporal knowledge graph reasoning (TKGR) aims to predict future events by inferring missing entities with dynamic knowledge structures. Existing LLM-based reasoning methods prioritize contextual over structural relations, struggling to…

Machine Learning · Computer Science 2026-01-30 Shiqi Fan , Quanming Yao , Hongyi Nie , Wentao Ma , Zhen Wang , Wen Hua

Generative AI, particularly Large Language Models, increasingly integrates graph-based representations to enhance reasoning, retrieval, and structured decision-making. Despite rapid advances, there remains limited clarity regarding when,…

Artificial Intelligence · Computer Science 2026-04-21 Hamed Jelodar , Samita Bai , Mohammad Meymani , Parisa Hamedi , Roozbeh Razavi-Far , Ali Ghorbani

Neural-based learning agents make decisions using internal artificial neural networks. In certain situations, it becomes pertinent that this knowledge is re-interpreted in a friendly form to both the human and the machine. These situations…

Multiagent Systems · Computer Science 2022-04-04 Duy Tung Nguyen , Kathryn Kasmarik , Hussein Abbass

The increasing use of generative artificial intelligence (GenAI) in qualitative research raises important questions about analytic practice and interpretive authority. This study examines how researchers interact with an Inductive Thematic…

Artificial Intelligence · Computer Science 2026-01-21 Matthew Nyaaba , Min SungEun , Mary Abiswin Apam , Kwame Owoahene Acheampong , Emmanuel Dwamena , Xiaoming Zhai

The goal of this work is to address two limitations in autoencoder-based models: latent space interpretability and compatibility with unstructured meshes. This is accomplished here with the development of a novel graph neural network (GNN)…

Machine Learning · Computer Science 2023-02-20 Shivam Barwey , Varun Shankar , Venkatasubramanian Viswanathan , Romit Maulik

Recent advances in Generative AI have transformed how users interact with data analysis through natural language interfaces. However, many systems rely too heavily on LLMs, creating risks of hallucination, opaque reasoning, and reduced user…

Human-Computer Interaction · Computer Science 2025-09-04 Ratanond Koonchanok , Alex Kale , Khairi Reda

This study explores the integration of multiple Explainable AI (XAI) techniques to enhance the interpretability of deep learning models for brain tumour detection. A custom Convolutional Neural Network (CNN) was developed and trained on the…

Artificial Intelligence · Computer Science 2026-02-06 Patrick McGonagle , William Farrelly , Kevin Curran

We introduce generative interpretation, a new approach to estimating contractual meaning using large language models. As AI triumphalism is the order of the day, we proceed by way of grounded case studies, each illustrating the capabilities…

Computation and Language · Computer Science 2023-08-15 Yonathan A. Arbel , David Hoffman

This review introduces the transformative potential of generative Artificial Intelligence (AI) and foundation models, including large language models (LLMs), for health technology assessment (HTA). We explore their applications in four…

Machine Learning · Computer Science 2024-09-24 Rachael Fleurence , Jiang Bian , Xiaoyan Wang , Hua Xu , Dalia Dawoud , Mitch Higashi , Jagpreet Chhatwal

Graphs serve as generic tools to encode the underlying relational structure of data. Often this graph is not given, and so the task of inferring it from nodal observations becomes important. Traditional approaches formulate a convex inverse…

Machine Learning · Computer Science 2024-06-24 Max Wasserman , Gonzalo Mateos

We present S-Path-RAG, a semantic-aware shortest-path Retrieval-Augmented Generation framework designed to improve multi-hop question answering over large knowledge graphs. S-Path-RAG departs from one-shot, text-heavy retrieval by…

Computation and Language · Computer Science 2026-03-26 Rong Fu , Yemin Wang , Tianxiang Xu , Yongtai Liu , Weizhi Tang , Wangyu Wu , Xiaowen Ma , Simon Fong

Interpreting complex neural networks is crucial for understanding their decision-making processes, particularly in applications where transparency and accountability are essential. This proposed method addresses this need by focusing on…

Neural and Evolutionary Computing · Computer Science 2024-12-10 Deepshikha Bhati , Fnu Neha , Md Amiruzzaman , Angela Guercio , Deepak Kumar Shukla , Ben Ward