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Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

Deep learning-based medical image segmentation faces significant challenges arising from limited labeled data and domain shifts. While prior approaches have primarily addressed these issues independently, their simultaneous occurrence is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Zanting Ye , Ke Wang , Wenbing Lv , Qianjin Feng , Lijun Lu

Although deep learning models like CNNs have achieved great success in medical image analysis, the small size of medical datasets remains a major bottleneck in this area. To address this problem, researchers have started looking for…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Xiaozheng Xie , Jianwei Niu , Xuefeng Liu , Zhengsu Chen , Shaojie Tang , Shui Yu

Standard supervised learning setting assumes that training data and test data come from the same distribution (domain). Domain generalization (DG) methods try to learn a model that when trained on data from multiple domains, would…

Computer Vision and Pattern Recognition · Computer Science 2020-08-18 Udit Maniyar , Joseph K J , Aniket Anand Deshmukh , Urun Dogan , Vineeth N Balasubramanian

Despite the recent success of domain generalization in medical image segmentation, voxel-wise annotation for all source domains remains a huge burden. Semi-supervised domain generalization has been proposed very recently to combat this…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Muyang Qiu , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

Federated learning enables collaborative model training across geographically distributed medical centers while preserving data privacy. However, domain shifts and heterogeneity in data often lead to a degradation in model performance.…

Data fabric is an automated and AI-driven data fusion approach to accomplish data management unification without moving data to a centralized location for solving complex data problems. In a Federated learning architecture, the global model…

Federated learning is the process of developing machine learning models over datasets distributed across data centers such as hospitals, clinical research labs, and mobile devices while preventing data leakage. This survey examines previous…

Machine Learning · Computer Science 2022-11-22 Madhura Joshi , Ankit Pal , Malaikannan Sankarasubbu

Artificial intelligence has transformed the perspective of medical imaging, leading to a genuine technological revolution in modern computer-assisted healthcare systems. However, ubiquitously featured deep learning (DL) systems require…

Image and Video Processing · Electrical Eng. & Systems 2026-01-09 Dominika Ciupek , Maciej Malawski , Tomasz Pieciak

Medical imaging is a domain which suffers from a paucity of manually annotated data for the training of learning algorithms. Manually delineating pathological regions at a pixel level is a time consuming process, especially in 3D images,…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Christopher Bowles , Roger Gunn , Alexander Hammers , Daniel Rueckert

Health information is generally fragmented across silos. Though it is technically feasible to unite data for analysis in a manner that underpins a rapid learning healthcare system, privacy concerns and regulatory barriers limit data…

Machine Learning · Computer Science 2020-12-10 Dianbo Liu , Kathe Fox , Griffin Weber , Tim Miller

Data privacy has become a major concern in healthcare due to the increasing digitization of medical records and data-driven medical research. Protecting sensitive patient information from breaches and unauthorized access is critical, as…

Digitization techniques for biomedical images yield different visual patterns in radiological exams. These differences may hamper the use of data-driven approaches for inference over these images, such as Deep Neural Networks. Another…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Hugo Oliveira , Edemir Ferreira , Jefersson A. dos Santos

Image normalization is a building block in medical image analysis. Conventional approaches are customarily utilized on a per-dataset basis. This strategy, however, prevents the current normalization algorithms from fully exploiting the…

Machine Learning · Computer Science 2020-10-06 Pierre-Luc Delisle , Benoit Anctil-Robitaille , Christian Desrosiers , Herve Lombaert

Domain generalization involves learning a classifier from a heterogeneous collection of training sources such that it generalizes to data drawn from similar unknown target domains, with applications in large-scale learning and personalized…

Machine Learning · Computer Science 2021-12-24 Xavier Thomas , Dhruv Mahajan , Alex Pentland , Abhimanyu Dubey

Due to medical data privacy regulations, it is often infeasible to collect and share patient data in a centralised data lake. This poses challenges for training machine learning algorithms, such as deep convolutional networks, which often…

Computer Vision and Pattern Recognition · Computer Science 2019-10-03 Wenqi Li , Fausto Milletarì , Daguang Xu , Nicola Rieke , Jonny Hancox , Wentao Zhu , Maximilian Baust , Yan Cheng , Sébastien Ourselin , M. Jorge Cardoso , Andrew Feng

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-15 Yundong Zhang , Hang Wu , Huiye Liu , Li Tong , May D Wang

We present MaskGen, a theoretically grounded and deliberately simple approach for domain generalization in 3D biomedical image segmentation. Modern segmentation models degrade sharply under shifts in modality, disease severity, clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebo Diaz , Polina Golland , Elfar Adalsteinsson , Neel Dey

Self-supervised learning (SSL) has emerged as a promising paradigm in medical imaging, addressing the chronic challenge of limited labeled data in healthcare settings. While SSL has shown impressive results, existing studies in the medical…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Valay Bundele , Karahan Sarıtaş , Bora Kargi , Oğuz Ata Çal , Kıvanç Tezören , Zohreh Ghaderi , Hendrik Lensch

In the problem of domain generalization (DG), there are labeled training data sets from several related prediction problems, and the goal is to make accurate predictions on future unlabeled data sets that are not known to the learner. This…

Machine Learning · Statistics 2021-01-08 Gilles Blanchard , Aniket Anand Deshmukh , Urun Dogan , Gyemin Lee , Clayton Scott