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The amount of data for machine learning (ML) applications is constantly growing. Not only the number of observations, especially the number of measured variables (features) increases with ongoing digitization. Selecting the most appropriate…

Machine Learning · Computer Science 2021-11-25 Konstantin Hopf , Sascha Reifenrath

Previous studies on computer aided detection/diagnosis (CAD) in 4D breast magnetic resonance imaging (MRI) regard lesion detection, segmentation and characterization as separate tasks, and typically require users to manually select 2D MRI…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Hang Min , Darryl McClymont , Shekhar S. Chandra , Stuart Crozier , Andrew P. Bradley

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

Breast ultrasound (US) is an effective imaging modality for breast cancer detection and diagnosis. US computer-aided diagnosis (CAD) systems have been developed for decades and have employed either conventional hand-crafted features or…

Medical Physics · Physics 2020-03-12 Erlei Zhang , Stephen Seiler , Mingli Chen , Weiguo Lu , Xuejun Gu

The use of machine learning (ML) in high-stakes societal decisions has encouraged the consideration of fairness throughout the ML lifecycle. Although data integration is one of the primary steps to generate high quality training data, most…

Machine Learning · Computer Science 2022-04-01 Sainyam Galhotra , Karthikeyan Shanmugam , Prasanna Sattigeri , Kush R. Varshney

The uncontrolled and unstructured growth of brain cells is known as brain tumor, which has one of the highest mortality rates among diseases from all types of cancers. Due to limited diagnostic and treatment capabilities, they pose…

Machine Learning · Computer Science 2024-04-02 PoTsang B. Huang , Muhammad Rizwan , Mehboob Ali

Computer aided diagnosis (CAD) of Breast Cancer (BRCA) images has been an active area of research in recent years. The main goals of this research is to develop reliable automatic methods for detecting and diagnosing different types of BRCA…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Marco A. V. M. Grinet , Nuno M. Garcia , Ana I. R. Gouveia , Jose A. F. Moutinho , Abel J. P. Gomes

The challenges in feature selection, particularly in balancing model accuracy, interpretability, and computational efficiency, remain a critical issue in advancing machine learning methodologies. To address these complexities, this study…

Machine Learning · Computer Science 2026-01-06 Nachiket Kapure , Harsh Joshi , Parul Kumari , Rajeshwari Mistri , Manasi Mali

More attention is being paid for feature importance ranking (FIR), in particular when thousands of features can be extracted for intelligent diagnosis and personalized medicine. A large number of FIR approaches have been proposed, while few…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Shaode Yu , Zhicheng Zhang , Xiaokun Liang , Junjie Wu , Erlei Zhang , Wenjian Qin , Yaoqin Xie

Background. Breast cancer screening programs using mammography have led to significant mortality reduction in high-income countries. However, many low- and middle-income countries lack resources for mammographic screening. Handheld breast…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Arianna Bunnell , Dustin Valdez , Fredrik Strand , Yannik Glaser , Peter Sadowski , John A. Shepherd

In medical applications such as recognizing the type of a tumor as Malignant or Benign, a wrong diagnosis can be devastating. Methods like Fuzzy Support Vector Machines (FSVM) try to reduce the effect of misplaced training points by…

Machine Learning · Computer Science 2013-04-12 Marzieh Parandehgheibi

Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H Graham , Lois Browne , Arcot Sowmya , Erik Meijering

Breast cancer has the highest mortality among cancers in women. Computer-aided pathology to analyze microscopic histopathology images for diagnosis with an increasing number of breast cancer patients can bring the cost and delays of…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Abhijeet Patil , Dipesh Tamboli , Swati Meena , Deepak Anand , Amit Sethi

The challenge in biomarker discovery using machine learning from omics data lies in the abundance of molecular features but scarcity of samples. Most feature selection methods in machine learning require evaluating various sets of features…

Quantitative Methods · Quantitative Biology 2025-01-03 Luca Cattelani , Vittorio Fortino

We investigate feature selection problem for generic machine learning models. We introduce a novel framework that selects features considering the outcomes of the model. Our framework introduces a novel feature masking approach to eliminate…

Machine Learning · Computer Science 2024-12-10 Mehmet E. Lorasdagi , Mehmet Y. Turali , Suleyman S. Kozat

Machine learning (ML) models are becoming integral in healthcare technologies, presenting a critical need for formal assurance to validate their safety, fairness, robustness, and trustworthiness. These models are inherently prone to errors,…

Breast cancer is a highly heterogeneous disease with diverse molecular profiles. The PAM50 gene signature is widely recognized as a standard for classifying breast cancer into intrinsic subtypes, enabling more personalized treatment…

Aim: To review how machine learning (ML) is applied to imaging biomarkers in neuro-oncology, in particular for diagnosis, prognosis, and treatment response monitoring. Materials and Methods: The PubMed and MEDLINE databases were searched…

Quantitative Methods · Quantitative Biology 2019-10-17 Thomas Booth , Matthew Williams , Aysha Luis , Jorge Cardoso , Ashkan Keyoumars , Haris Shuaib

Effective preoperative planning requires accurate algorithms for segmenting anatomical structures across diverse datasets, but traditional models struggle with generalization. This study presents a novel machine learning methodology to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Mustafa Khanbhai , Giulia Di Nardo , Jun Ma , Vivienne Freitas , Caterina Masino , Ali Dolatabadi , Zhaoxun "Lorenz" Liu , Wey Leong , Wagner H. Souza , Amin Madani

Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…

Machine Learning · Computer Science 2019-08-20 Sterling Ramroach , Melford John , Ajay Joshi