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Is it possible to generally construct a dynamical system to simulate a black system without recovering the equations of motion of the latter? Here we show that this goal can be approached by a learning machine. Trained by a set of…

Machine Learning · Statistics 2022-04-15 Hong Zhao

A model of a discrete pregeometry on a microscopic scale is introduced. This model is a finite network of finite elementary processes. The mathematical description is a d-graph that is a generalization of a graph. This is the particular…

General Relativity and Quantum Cosmology · Physics 2010-04-29 Alexey L. Krugly

We describe a computational model for studying the complexity of self-assembled structures with active molecular components. Our model captures notions of growth and movement ubiquitous in biological systems. The model is inspired by…

Data Structures and Algorithms · Computer Science 2013-01-15 Damien Woods , Ho-Lin Chen , Scott Goodfriend , Nadine Dabby , Erik Winfree , Peng Yin

The study of organoids, artificially grown cell aggregates with the functionality and small-scale anatomy of real organs, is one of the most active areas of research in biology and biophysics, yet the basic physical origins of their…

Biological Physics · Physics 2021-10-12 Jan Rozman , Matej Krajnc , Primož Ziherl

When deployed in the wild, machine learning models are usually confronted with data and requirements that constantly vary, either because of changes in the generating distribution or because external constraints change the environment where…

Machine Learning · Computer Science 2020-07-17 Irene Unceta , Jordi Nin , Oriol Pujol

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

Biological Physics · Physics 2008-03-07 Debashish Chowdhury

Cells of the human body have nearly identical genome but exhibit very different phenotypes that allow them to carry out specific functions and react to changes in their surrounding environment. This division of labour is achieved by…

Cell Behavior · Quantitative Biology 2021-11-24 Hanan Dreiwi , Flavia Feliciangeli , Mario Castro , Grant Lythe , Carmen Molina-París , Martín López-García

Our knowledge of how individual cells self-organize to form complex multicellular systems is being revolutionized by a data outburst, coming from high-throughput experimental breakthroughs such as single-cell RNA sequencing and spatially…

Cell Behavior · Quantitative Biology 2021-04-20 Gabriel Torregrosa , Jordi Garcia-Ojalvo

The applicability of computational models to the biological world is an active topic of debate. We argue that a useful path forward results from abandoning hard boundaries between categories and adopting an observer-dependent, pragmatic…

Multiagent Systems · Computer Science 2022-12-22 Joshua Bongard , Michael Levin

In the paper we present results to develop an irreducible theory of complex systems in terms of self-organization processes of prime integer relations. Based on the integers and controlled by arithmetic only the self-organization processes…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Victor Korotkikh , Galina Korotkikh

Creating autonomous, self-supporting, self-replicating, sustainable systems is a great challenge. To some extent, understanding life means not only being able to create it from scratch, but also improving, supporting, saving it, or even…

Robotics · Computer Science 2011-11-07 Serge Kernbach

Mathematical models are increasingly used in both academia and the pharmaceutical industry to understand how phenotypes emerge from systems of molecular interactions. However, their current construction as monolithic sets of equations…

Molecular Networks · Quantitative Biology 2007-10-19 Aneil Mallavarapu , Matthew Thomson , Benjamin Ullian , Jeremy Gunawardena

Molecular biology explains function of molecules by their geometrical and electronical structures that are mainly determined by utilization of quantum effects in chemistry. However, further quantum effects are not thought to play any…

Quantum Physics · Physics 2011-12-30 Onur Pusuluk , Cemsinan Deliduman

We introduce and analyze a model for self-reconfigurable robots made up of unit-cube modules. Compared to past models, our model aims to newly capture two important practical aspects of real-world robots. First, modules often do not occupy…

We study primary submodules and primary decompositions from a differential and computational point of view. Our main theoretical contribution is a general structure theory and a representation theorem for primary submodules of an arbitrary…

Commutative Algebra · Mathematics 2022-02-15 Justin Chen , Yairon Cid-Ruiz

A computer simulation has to be fast to be helpful, if it is employed to study the behavior of a multicomponent dynamic system. This paper discusses modeling concepts and algorithmic techniques useful for creating such fast simulations.…

Data Structures and Algorithms · Computer Science 2007-05-23 Boris D. Lubachevsky

We present a deep imitation learning framework for robotic bimanual manipulation in a continuous state-action space. A core challenge is to generalize the manipulation skills to objects in different locations. We hypothesize that modeling…

Biological cells are built up from many different constituents of varying size and stiffness which all contribute to the cell's mechanical properties. Despite this heterogeneity, in the analysis of experimental measurements such as atomic…

Biological Physics · Physics 2023-05-18 Sebastian Wohlrab , Sebastian J. Müller , Stephan Gekle

Deep Learning models enjoy considerable success in Natural Language Processing. While deep architectures produce useful representations that lead to improvements in various tasks, they are often difficult to interpret. This makes the…

Computation and Language · Computer Science 2013-04-29 Christian Scheible , Hinrich Schuetze

We are entering a new era in which software systems are becoming more and more complex and larger. So, the composition of such systems is becoming infeasible by manual means. To address this challenge, self-organising software models…

Formal Languages and Automata Theory · Computer Science 2025-08-27 Damian Arellanes