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Denoising diffusion probabilistic models have recently received much research attention since they outperform alternative approaches, such as GANs, and currently provide state-of-the-art generative performance. The superior performance of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Dmitry Baranchuk , Ivan Rubachev , Andrey Voynov , Valentin Khrulkov , Artem Babenko

Data augmentation for domain-specific image classification tasks often struggles to simultaneously address diversity, faithfulness, and label clarity of generated data, leading to suboptimal performance in downstream tasks. While existing…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yixuan Dong , Fang-Yi Su , Jung-Hsien Chiang

Recent advances in Diffusion Probabilistic Models (DPMs) have set new standards in high-quality image synthesis. Yet, controlled generation remains challenging, particularly in sensitive areas such as medical imaging. Medical images feature…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Sarah Cechnicka , Matthew Baugh , Weitong Zhang , Mischa Dombrowski , Zhe Li , Johannes C. Paetzold , Candice Roufosse , Bernhard Kainz

Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Saghir Alfasly , Wataru Uegami , MD Enamul Hoq , Ghazal Alabtah , H. R. Tizhoosh

In digital pathology, the spatial context of cells is important for cell classification, cancer diagnosis and prognosis. To model such complex cell context, however, is challenging. Cells form different mixtures, lineages, clusters and…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Shahira Abousamra , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

We investigate whether synthetic images generated by diffusion models can enhance multi-label classification of protein subcellular localization. Specifically, we implement a simplified class-conditional denoising diffusion probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Sylvey Lin , Zhi-Yi Cao

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Data augmentation plays a crucial role in deep learning, enhancing the generalization and robustness of learning-based models. Standard approaches involve simple transformations like rotations and flips for generating extra data. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Shichao Dong , Ze Yang , Guosheng Lin

Collecting pixel-level labels for medical datasets can be a laborious and expensive process, and enhancing segmentation performance with a scarcity of labeled data is a crucial challenge. This work introduces AugPaint, a data augmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Xinrong Hu , Yiyu Shi

Data augmentation is a ubiquitous technique for increasing the size of labeled training sets by leveraging task-specific data transformations that preserve class labels. While it is often easy for domain experts to specify individual…

Machine Learning · Statistics 2018-12-10 Alexander J. Ratner , Henry R. Ehrenberg , Zeshan Hussain , Jared Dunnmon , Christopher Ré

Supervised deep learning for semantic segmentation has achieved excellent results in accurately identifying anatomical and pathological structures in medical images. However, it often requires large annotated training datasets, which limits…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Luca Ciampi , Gabriele Lagani , Giuseppe Amato , Fabrizio Falchi

Deep Learning models are incredibly data-hungry and require very large labeled datasets for supervised learning. As a consequence, these models often suffer from overfitting, limiting their ability to generalize to real-world examples.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Sahiti Yerramilli , Jayant Sravan Tamarapalli , Tanmay Girish Kulkarni , Jonathan Francis , Eric Nyberg

Supervised deep learning methods for segmentation require large amounts of labelled training data, without which they are prone to overfitting, not generalizing well to unseen images. In practice, obtaining a large number of annotations…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Krishna Chaitanya , Neerav Karani , Christian Baumgartner , Olivio Donati , Anton Becker , Ender Konukoglu

In computational pathology, researchers often face challenges due to the scarcity of labeled pathology datasets. Data augmentation emerges as a crucial technique to mitigate this limitation. In this study, we introduce an efficient data…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Jiamu Wang , Jin Tae Kwak

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Xiaodan Xing , Junzhi Ning , Yang Nan , Guang Yang

Diffusion models has underpinned much recent advances of dataset augmentation in various computer vision tasks. However, when involving generating multi-object images as real scenarios, most existing methods either rely entirely on text…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Haoyu Wang , Lei Zhang , Wei Wei , Chen Ding , Yanning Zhang

Despite significant advancements in multi-label text classification, the ability of existing models to generalize to novel and seldom-encountered complex concepts, which are compositions of elementary ones, remains underexplored. This…

Computation and Language · Computer Science 2023-12-21 Yuyang Chai , Zhuang Li , Jiahui Liu , Lei Chen , Fei Li , Donghong Ji , Chong Teng

To synthesize high-fidelity samples, diffusion models typically require auxiliary data to guide the generation process. However, it is impractical to procure the painstaking patch-level annotation effort required in specialized domains like…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Alexandros Graikos , Srikar Yellapragada , Minh-Quan Le , Saarthak Kapse , Prateek Prasanna , Joel Saltz , Dimitris Samaras

Semantic segmentation is a computer vision task where classification is performed at a pixel level. Due to this, the process of labeling images for semantic segmentation is time-consuming and expensive. To mitigate this cost there has been…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Javier Montalvo , Álvaro García-Martín , Pablo Carballeira , Juan C. SanMiguel