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We develop and analyze explainable machine learning (ML) models for sepsis outcome prediction using a novel Electronic Health Record (EHR) dataset from 12,286 hospitalizations at a large emergency hospital in Romania. The dataset includes…

Machine Learning · Computer Science 2026-04-07 Andrei-Alexandru Bunea , Ovidiu Ghibea , Dan-Matei Popovici , Ion Daniel , Octavian Andronic

A huge amount of medical data is generated every day, which presents a challenge in analysing these data. The obvious solution to this challenge is to reduce the amount of data without information loss. Dimension reduction is considered the…

Computers and Society · Computer Science 2015-11-24 Noura AlNuaimi , Mohammad M Masud , Farhan Mohammed

Background and Purpose: Identifying the thromboembolism source in ischemic stroke is crucial for treatment and secondary prevention yet is often undetermined. This study describes a self-supervised deep learning approach in digital…

Computer Vision and Pattern Recognition · Computer Science 2024-05-03 K. Yeh , M. S. Jabal , V. Gupta , D. F. Kallmes , W. Brinjikji , B. S. Erdal

Acute myocardial infarction (AMI) is one of the most severe manifestation of coronary artery disease. ST-segment elevation myocardial infarction (STEMI) is the most serious type of AMI. We proposed to develop a machine learning algorithm…

Quantitative Methods · Quantitative Biology 2022-11-29 Ding Tao , Chen Liu , Shihan Wan

The Intensive Care Unit (ICU) is a hospital department where machine learning has the potential to provide valuable assistance in clinical decision making. Classical machine learning models usually only provide point-estimates and no…

Machine Learning · Computer Science 2024-07-26 David Ruhe , Giovanni Cinà , Michele Tonutti , Daan de Bruin , Paul Elbers

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

Hyperkalemia is a potentially life-threatening condition that can lead to fatal arrhythmias. Early identification of high risk patients can inform clinical care to mitigate the risk. While hyperkalemia is often a complication of acute…

Machine Learning · Computer Science 2021-01-28 Gloria Hyunjung Kwak , Christina Chen , Lowell Ling , Erina Ghosh , Leo Anthony Celi , Pan Hui

Cardiac arrest remains a leading cause of death worldwide, necessitating proactive measures for early detection and intervention. This project aims to develop and assess predictive models for the timely identification of cardiac arrest…

Computers and Society · Computer Science 2024-09-25 G. Divya , M. Naga SravanKumar , T. JayaDharani , B. Pavan , K. Praveen

Computer vision models can be used to assist during mechanical thrombectomy (MT) for acute ischemic stroke (AIS), but poor image quality often degrades performance. This work presents CLAIRE-DSA, a deep learning--based framework designed to…

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

Stroke is known as a major global health problem, and for stroke survivors it is key to monitor the recovery levels. However, traditional stroke rehabilitation assessment methods (such as the popular clinical assessment) can be subjective…

Signal Processing · Electrical Eng. & Systems 2022-12-27 Xi Chen , Yu Guan , Jian Qing Shi , Xiu-Li Du , Janet Eyre

The ability to perform accurate prognosis of patients is crucial for proactive clinical decision making, informed resource management and personalised care. Existing outcome prediction models suffer from a low recall of infrequent positive…

Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect…

Machine Learning · Computer Science 2018-06-28 Tony Wang , Tom Velez , Emilia Apostolova , Tim Tschampel , Thuy L. Ngo , Joy Hardison

Paralytic Ileus (PI) patients are at high risk of death when admitted to the Intensive care unit (ICU), with mortality as high as 40\%. There is minimal research concerning PI patient mortality prediction. There is a need for more accurate…

Machine Learning · Computer Science 2021-08-04 Maryam Pishgar , Martha Razo , Julian Theis , Houshang Darabi

Currently, strokes are the leading cause of adult disability in the United States. Traditional treatment and rehabilitation options such as physical therapy and tissue plasminogen activator are limited in their effectiveness and ability to…

Signal Processing · Electrical Eng. & Systems 2020-08-20 Mohammad-Parsa Hosseini , Cecilia Hemingway , Jerard Madamba , Alexander McKee , Natalie Ploof , Jennifer Schuman , Elliot Voss

The recent increase in morbidity is primarily due to chronic diseases including Diabetes, Heart disease, Lung cancer, and brain tumours. The results for patients can be improved, and the financial burden on the healthcare system can be…

Machine Learning · Computer Science 2025-02-18 Sri Varsha Mulakala , G. Neeharika , P. Vinay Kumar , A. Bhargava Kiran

Mechanical thrombectomy has become the standard of care in patients with stroke due to large vessel occlusion (LVO). However, only 50% of successfully treated patients show a favorable outcome. We developed and evaluated interpretable deep…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Lisa Herzog , Pascal Bühler , Ezequiel de la Rosa , Beate Sick , Susanne Wegener

In the United States, more than 5 million patients are admitted annually to ICUs, with ICU mortality of 10%-29% and costs over $82 billion. Acute brain dysfunction status, delirium, is often underdiagnosed or undervalued. This study's…

In machine learning larger databases are usually associated with higher classification accuracy due to better generalization. This generalization may lead to non-optimal classifiers in some medical applications with highly variable…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Michael Götz , Christian Weber , Christoph Kolb , Klaus Maier-Hein

More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Luca Tomasetti , Kjersti Engan , Mahdieh Khanmohammadi , Kathinka Dæhli Kurz