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Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Algorithms proposed for solving high-dimensional optimization problems with no derivative information frequently encounter the "curse of dimensionality," becoming ineffective as the dimension of the parameter space grows. One feature of a…

Optimization and Control · Mathematics 2020-04-28 Dmitry Pozharskiy , Noah J. Wichrowski , Andrew B. Duncan , Grigorios A. Pavliotis , Ioannis G. Kevrekidis

In this paper, a fine-tuning method of the parameters in the MMG model for the real-scale ship is proposed. In the proposed method, all of the arbitrarily indicated target parameters of the MMG model are tuned simultaneously in the…

Systems and Control · Electrical Eng. & Systems 2023-12-08 Rin Suyama , Rintaro Matsushita , Ryo Kakuta , Kouki Wakita , Atsuo Maki

Previous attempts to integrate Neural Radiance Fields (NeRF) into the Simultaneous Localization and Mapping (SLAM) framework either rely on the assumption of static scenes or require the ground truth camera poses, which impedes their…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Chengyao Duan , Zhiliu Yang

Driving scenario data play an increasingly vital role in the development of intelligent vehicles and autonomous driving. Accurate and efficient scenario data search is critical for both online vehicle decision-making and planning, and…

Robotics · Computer Science 2025-04-08 Cheng Chang , Jingwei Ge , Jiazhe Guo , Zelin Guo , Binghong Jiang , Li Li

An important challenge in robotics is understanding the interactions between robots and deformable terrains that consist of granular material. Granular flows and their interactions with rigid bodies still pose several open questions. A…

Machine Learning · Computer Science 2021-11-22 Amin Haeri , Krzysztof Skonieczny

The extensive adoption of Deep Neural Networks has led to their increased utilization in challenging scientific visualization tasks. Recent advancements in building compressed data models using implicit neural representations have shown…

Machine Learning · Computer Science 2025-10-20 Abhay Kumar Dwivedi , Shanu Saklani , Soumya Dutta

Real-time simulation of elastic structures is essential in many applications, from computer-guided surgical interventions to interactive design in mechanical engineering. The Finite Element Method is often used as the numerical method of…

Machine Learning · Computer Science 2021-09-21 Alban Odot , Ryadh Haferssas , Stéphane Cotin

This technical note introduces parametric dynamic causal modelling, a method for inferring slow changes in biophysical parameters that control fluctuations of fast neuronal states. The application domain we have in mind is inferring slow…

Quantitative Methods · Quantitative Biology 2020-08-27 Amirhossein Jafarian , Peter Zeidman , Rob. C Wykes , Matthew Walker , Karl J. Friston

Surrogate models provide compact relations between user-defined input parameters and output quantities of interest, enabling the efficient evaluation of complex parametric systems in many-query settings. Such capabilities are essential in a…

Numerical Analysis · Mathematics 2026-03-16 Matteo Giacomini , Pedro Díez

Point-drag-based image editing methods, like DragDiffusion, have attracted significant attention. However, point-drag-based approaches suffer from computational overhead and misinterpretation of user intentions due to the sparsity of…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Jingyi Lu , Xinghui Li , Kai Han

Table Structure Recognition is an essential part of end-to-end tabular data extraction in document images. The recent success of deep learning model architectures in computer vision remains to be non-reflective in table structure…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Umar Khan , Sohaib Zahid , Muhammad Asad Ali , Adnan ul Hassan , Faisal Shafait

We present SoftSMPL, a learning-based method to model realistic soft-tissue dynamics as a function of body shape and motion. Datasets to learn such task are scarce and expensive to generate, which makes training models prone to overfitting.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Igor Santesteban , Elena Garces , Miguel A. Otaduy , Dan Casas

Physics-based character animation has become a fundamental approach for synthesizing realistic, physically plausible motions. While current data-driven deep reinforcement learning (DRL) methods can synthesize complex skills, they struggle…

Artificial Intelligence · Computer Science 2026-04-08 Zhiquan Wang , Bedrich Benes

We describe a framework for interactive molecular dynamics in a multiuser virtual reality environment, combining rigorous cloud-mounted physical atomistic simulation with commodity virtual reality hardware, which we have made accessible to…

Textual descriptions for multimodal inputs entail recurrent refinement of queries to produce relevant output images. Despite efforts to address challenges such as scaling model size and data volume, the cost associated with pre-training and…

Machine Learning · Computer Science 2025-08-14 Amit Kumar Jaiswal , Haiming Liu , Ingo Frommholz

Sensitivity analyses of simulation ensembles determine how simulation parameters influence the simulation's outcome. Commonly, one global numerical sensitivity value is computed per simulation parameter. However, when considering 3D spatial…

Human-Computer Interaction · Computer Science 2024-08-08 Marina Evers , Simon Leistikow , Hennes Rave , Lars Linsen

In this paper, we present the Draw-and-Understand framework, exploring how to integrate visual prompting understanding capabilities into Multimodal Large Language Models (MLLMs). Visual prompts allow users to interact through multi-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Weifeng Lin , Xinyu Wei , Ruichuan An , Peng Gao , Bocheng Zou , Yulin Luo , Siyuan Huang , Shanghang Zhang , Hongsheng Li

Key feature fields need bigger embedding dimensionality, others need smaller. This demands automated dimension allocation. Existing approaches, such as pruning or Neural Architecture Search (NAS), require training a memory-intensive…

Machine Learning · Computer Science 2025-05-20 Yihong Huang , Chen Chu

Molecular dynamics (MD) simulation is essential for various scientific domains but computationally expensive. Learning-based force fields have made significant progress in accelerating ab-initio MD simulation but are not fast enough for…

Machine Learning · Computer Science 2023-08-29 Xiang Fu , Tian Xie , Nathan J. Rebello , Bradley D. Olsen , Tommi Jaakkola