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Laboratory testing and medication prescription are two of the most important routines in daily clinical practice. Developing an artificial intelligence system that can automatically make lab test imputations and medication recommendations…

Machine Learning · Computer Science 2022-02-07 Chengsheng Mao , Liang Yao , Yuan Luo

While large language models (LLMs) have been successfully applied to various tasks, they still face challenges with hallucinations. Augmenting LLMs with domain-specific tools such as database utilities can facilitate easier and more precise…

Computation and Language · Computer Science 2024-04-10 Qiao Jin , Yifan Yang , Qingyu Chen , Zhiyong Lu

Biomedical knowledge graphs (KGs) hold rich information on entities such as diseases, drugs, and genes. Predicting missing links in these graphs can boost many important applications, such as drug design and repurposing. Recent work has…

Computation and Language · Computer Science 2021-09-22 Rahul Nadkarni , David Wadden , Iz Beltagy , Noah A. Smith , Hannaneh Hajishirzi , Tom Hope

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

Machine Learning · Computer Science 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

The widespread adoption of electronic health records has created new opportunities for translational clinical research, yet this promise remains constrained by fragmented data across privacy-siloed institutions and substantial heterogeneity…

Knowledge graph completion (KGC) seeks to predict missing entities (e.g., heads or tails) or relationships in knowledge graphs (KGs), which often contain incomplete data. Traditional embedding-based methods, such as TransE and ComplEx, have…

Computation and Language · Computer Science 2025-03-11 Haji Gul , Ajaz Ahmad Bhat , Abdul Ghani Haji Naim

Drug-drug interactions (DDIs) are a major concern in clinical practice, as they can lead to reduced therapeutic efficacy or severe adverse effects. Traditional computational approaches often struggle to capture the complex relationships…

Machine Learning · Computer Science 2025-08-27 Hongbo Liu , Siyi Li , Zheng Yu

The advent of large language models (LLMs) has revolutionized the integration of knowledge graphs (KGs) in biomedical and cognitive sciences, overcoming limitations in traditional machine learning methods for capturing intricate semantic…

Artificial Intelligence · Computer Science 2025-10-09 Ali Sarabadani , Kheirolah Rahsepar Fard

Knowledge graphs (KGs) are powerful tools for representing and reasoning over structured information. Their main components include schema, identity, and context. While schema and identity matching are well-established in ontology and…

Computation and Language · Computer Science 2025-08-01 Victor Eiti Yamamoto , Hideaki Takeda

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge…

Computation and Language · Computer Science 2025-02-18 Mingyi Jia , Junwen Duan , Yan Song , Jianxin Wang

Treatment effect estimation (TEE) is the task of determining the impact of various treatments on patient outcomes. Current TEE methods fall short due to reliance on limited labeled data and challenges posed by sparse and high-dimensional…

Machine Learning · Computer Science 2024-03-07 Ruoqi Liu , Lingfei Wu , Ping Zhang

The graph structure of biomedical data differs from those in typical knowledge graph benchmark tasks. A particular property of biomedical data is the presence of long-range dependencies, which can be captured by patterns described as…

Machine Learning · Computer Science 2020-07-13 Yushan Liu , Marcel Hildebrandt , Mitchell Joblin , Martin Ringsquandl , Volker Tresp

Recent advancements in Large Language Models (LLMs) have showcased their proficiency in answering natural language queries. However, their effectiveness is hindered by limited domain-specific knowledge, raising concerns about the…

This paper introduces Helix, a distributed system for high-throughput, low-latency large language model (LLM) serving in heterogeneous GPU clusters. The key idea behind Helix is to formulate inference computation of LLMs over heterogeneous…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-07 Yixuan Mei , Yonghao Zhuang , Xupeng Miao , Juncheng Yang , Zhihao Jia , Rashmi Vinayak

We describe team ielab from CSIRO and The University of Queensland's approach to the 2023 TREC Clinical Trials Track. Our approach was to use neural rankers but to utilise Large Language Models to overcome the issue of lack of training data…

Information Retrieval · Computer Science 2024-01-04 Shengyao Zhuang , Bevan Koopman , Guido Zuccon

Federated graph learning (FGL) has emerged as a promising paradigm for collaborative graph representation learning, enabling multiple parties to jointly train models while preserving data privacy. However, most existing approaches assume…

Machine Learning · Computer Science 2026-01-01 Zhengyu Wu , Guang Zeng , Huilin Lai , Daohan Su , Jishuo Jia , Yinlin Zhu , Xunkai Li , Rong-Hua Li , Guoren Wang , Chenghu Zhou

Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…

Computation and Language · Computer Science 2025-07-01 Tien Dang , Viet Thanh Duy Nguyen , Minh Tuan Le , Truong-Son Hy

Multimodal knowledge graphs (MMKGs) enrich traditional knowledge graphs (KGs) by incorporating diverse modalities such as images and text. multimodal knowledge graph completion (MMKGC) seeks to exploit these heterogeneous signals to infer…

Computation and Language · Computer Science 2025-08-12 Yongkang Xiao , Rui Zhang

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Large Language Models (LLMs) have demonstrated remarkable capabilities in text generation and understanding, yet their reliance on implicit, unstructured knowledge often leads to factual inaccuracies and limited interpretability. Knowledge…

Computation and Language · Computer Science 2025-06-17 Qinggang Zhang
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