English
Related papers

Related papers: Decomposed Direct Preference Optimization for Stru…

200 papers

Diffusion models have achieved state-of-the-art performance across multiple domains, with recent advancements extending their applicability to discrete data. However, aligning discrete diffusion models with task-specific preferences remains…

Machine Learning · Computer Science 2025-04-10 Umberto Borso , Davide Paglieri , Jude Wells , Tim Rocktäschel

Text-to-image diffusion models deliver high-quality images, yet aligning them with human preferences remains challenging. We revisit diffusion-based Direct Preference Optimization (DPO) for these models and identify a critical pathology:…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Minghao Fu , Guo-Hua Wang , Tianyu Cui , Qing-Guo Chen , Zhao Xu , Weihua Luo , Kaifu Zhang

Recently, 3D generative models have shown promising performances in structure-based drug design by learning to generate ligands given target binding sites. However, only modeling the target-ligand distribution can hardly fulfill one of the…

Biomolecules · Quantitative Biology 2024-03-22 Xiangxin Zhou , Xiwei Cheng , Yuwei Yang , Yu Bao , Liang Wang , Quanquan Gu

Direct Preference Optimization (DPO) has emerged as a predominant alignment method for diffusion models, facilitating off-policy training without explicit reward modeling. However, its reliance on large-scale, high-quality human preference…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Khiem Pham , Quang Nguyen , Tung Nguyen , Jingsen Zhu , Michele Santacatterina , Dimitris Metaxas , Ramin Zabih

The practical applications of diffusion models have been limited by the misalignment between generated images and corresponding text prompts. Recent studies have introduced direct preference optimization (DPO) to enhance the alignment of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Zijing Hu , Fengda Zhang , Kun Kuang

Inverse folding models play an important role in structure-based design by predicting amino acid sequences that fold into desired reference structures. Models like ProteinMPNN, a message-passing encoder-decoder model, are trained to…

Machine Learning · Computer Science 2026-05-12 Ryan Park , Darren J. Hsu , C. Brian Roland , Maria Korshunova , Chen Tessler , Shie Mannor , Olivia Viessmann , Bruno Trentini

The inverse folding problem, aiming to design amino acid sequences that fold into desired three-dimensional structures, is pivotal for various biotechnological applications. Here, we introduce a novel approach leveraging Direct Preference…

Machine Learning · Computer Science 2025-06-04 Junde Xu , Zijun Gao , Xinyi Zhou , Jie Hu , Xingyi Cheng , Le Song , Guangyong Chen , Pheng-Ann Heng , Jiezhong Qiu

Direct Preference Optimization (DPO) aligns text-to-image (T2I) generation models with human preferences using pairwise preference data. Although substantial resources are expended in collecting and labeling datasets, a critical aspect is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Yunhong Lu , Qichao Wang , Hengyuan Cao , Xiaoyin Xu , Min Zhang

Generating visually appealing images is fundamental to modern text-to-image generation models. A potential solution to better aesthetics is direct preference optimization (DPO), which has been applied to diffusion models to improve general…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Zhanhao Liang , Yuhui Yuan , Shuyang Gu , Bohan Chen , Tiankai Hang , Mingxi Cheng , Ji Li , Liang Zheng

Direct preference optimization (DPO) methods have shown strong potential in aligning text-to-image diffusion models with human preferences by training on paired comparisons. These methods improve training stability by avoiding the REINFORCE…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Yi-Lun Wu , Bo-Kai Ruan , Chiang Tseng , Hong-Han Shuai

Diffusion models have achieved remarkable success in generating realistic and versatile images from text prompts. Inspired by the recent advancements of language models, there is an increasing interest in further improving the models by…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Binxu Li , Minkai Xu , Jiaqi Han , Meihua Dang , Stefano Ermon

Direct Preference Optimization (DPO) guides large language models (LLMs) to generate recommendations aligned with user historical behavior distributions by minimizing preference alignment loss. However, our systematic empirical research and…

Information Retrieval · Computer Science 2026-05-28 Chu Zhao , Enneng Yang , Jianzhe Zhao , Guibing Guo

Diffusion models have achieved remarkable success in conditional image generation, yet their outputs often remain misaligned with human preferences. To address this, recent work has applied Direct Preference Optimization (DPO) to diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Shaomeng Wang , He Wang , Xiaolu Wei , Longquan Dai , Jinhui Tang

Direct Preference Optimization (DPO) is successful for alignment in LLMs but still faces challenges in text-to-image generation. Existing studies are confined to denoising diffusion models while overlooking flow-matching, and suffer from an…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Kesong Li , Yixuan Xu , Kuo-kun Tseng , Weiyi Lu , Kan Liu , Tao Lan

Diffusion Models have revolutionized the field of human motion generation by offering exceptional generation quality and fine-grained controllability through natural language conditioning. Their inherent stochasticity, that is the ability…

Computer Vision and Pattern Recognition · Computer Science 2024-05-08 Massimiliano Pappa , Luca Collorone , Giovanni Ficarra , Indro Spinelli , Fabio Galasso

Without using explicit reward, direct preference optimization (DPO) employs paired human preference data to fine-tune generative models, a method that has garnered considerable attention in large language models (LLMs). However, exploration…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Yunhong Lu , Qichao Wang , Hengyuan Cao , Xierui Wang , Xiaoyin Xu , Min Zhang

Direct Preference Optimization (DPO) have emerged as a popular method for aligning Large Language Models (LLMs) with human preferences. While DPO effectively preserves the relative ordering between chosen and rejected responses through…

Computation and Language · Computer Science 2025-06-05 Lin Sun , Chuang Liu , Peng Liu , Bingyang Li , Weijia Lu , Ning Wu

Direct Preference Optimization (DPO) is a simple and efficient framework that has attracted substantial attention. However, it often struggles to meet its primary objectives -- increasing the generation probability of chosen responses while…

Artificial Intelligence · Computer Science 2025-06-17 Jay Hyeon Cho , JunHyeok Oh , Myunsoo Kim , Byung-Jun Lee

Aligning text-to-video diffusion models with human preferences is crucial for generating high-quality videos. Existing Direct Preference Otimization (DPO) methods rely on multi-sample ranking and task-specific critic models, which is…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Zitong Huang , Kaidong Zhang , Yukang Ding , Chao Gao , Rui Ding , Ying Chen , Wangmeng Zuo

Direct preference optimization (DPO) is a successful fine-tuning strategy for aligning large language models with human preferences without the need to train a reward model or employ reinforcement learning. DPO, as originally formulated,…

Computation and Language · Computer Science 2024-06-07 Afra Amini , Tim Vieira , Ryan Cotterell
‹ Prev 1 2 3 10 Next ›