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Diffusion models excel at modeling complex data distributions, including those of images, proteins, and small molecules. However, in many cases, our goal is to model parts of the distribution that maximize certain properties: for example,…

This tutorial provides an in-depth guide on inference-time guidance and alignment methods for optimizing downstream reward functions in diffusion models. While diffusion models are renowned for their generative modeling capabilities,…

Artificial Intelligence · Computer Science 2025-01-22 Masatoshi Uehara , Yulai Zhao , Chenyu Wang , Xiner Li , Aviv Regev , Sergey Levine , Tommaso Biancalani

Diffusion models surpass previous generative models in sample quality and training stability. Recent works have shown the advantages of diffusion models in improving reinforcement learning (RL) solutions. This survey aims to provide an…

Machine Learning · Computer Science 2024-02-26 Zhengbang Zhu , Hanye Zhao , Haoran He , Yichao Zhong , Shenyu Zhang , Haoquan Guo , Tingting Chen , Weinan Zhang

Diffusion-based planning, learning, and control methods present a promising branch of powerful and expressive decision-making solutions. Given the growing interest, such methods have undergone numerous refinements over the past years.…

Machine Learning · Computer Science 2025-02-19 Dom Huh , Prasant Mohapatra

Text-to-image diffusion models are a class of deep generative models that have demonstrated an impressive capacity for high-quality image generation. However, these models are susceptible to implicit biases that arise from web-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Yinan Zhang , Eric Tzeng , Yilun Du , Dmitry Kislyuk

We address the problem of fine-tuning diffusion models for reward-guided generation in biomolecular design. While diffusion models have proven highly effective in modeling complex, high-dimensional data distributions, real-world…

Diffusion models have emerged as powerful tools for 3D medical image generation, yet bridging the gap between standard training objectives and clinical relevance remains a challenge. This paper presents a method to enhance 3D diffusion…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yueying Tian , Xudong Han , Meng Zhou , Rodrigo Aviles-Espinosa , Rupert Young , Philip Birch

Reinforcement Learning (RL) has recently been incorporated into diffusion models, e.g., tasks such as text-to-image. However, directly applying existing RL methods to diffusion-based image restoration models is suboptimal, as the objective…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Xiaogang Xu , Ruihang Chu , Jian Wang , Kun Zhou , Wenjie Shu , Harry Yang , Ser-Nam Lim , Hao Chen , Liang Lin

Diffusion Models (DMs), as a leading class of generative models, offer key advantages for reinforcement learning (RL), including multi-modal expressiveness, stable training, and trajectory-level planning. This survey delivers a…

Machine Learning · Computer Science 2025-10-15 Changfu Xu , Jianxiong Guo , Yuzhu Liang , Haiyang Huang , Haodong Zou , Xi Zheng , Shui Yu , Xiaowen Chu , Jiannong Cao , Tian Wang

Reinforcement learning (RL) struggles to scale to large, combinatorial action spaces common in many real-world problems. This paper introduces a novel framework for training discrete diffusion models as highly effective policies in these…

Machine Learning · Computer Science 2026-05-21 Haitong Ma , Ofir Nabati , Aviv Rosenberg , Bo Dai , Oran Lang , Craig Boutilier , Na Li , Shie Mannor , Lior Shani , Guy Tenneholtz

Diffusion models recently emerged as a powerful paradigm for recommender systems, offering state-of-the-art performance by modeling the generative process of user-item interactions. However, training such models from scratch is both…

Information Retrieval · Computer Science 2025-11-11 Yu Hou , Hua Li , Ha Young Kim , Won-Yong Shin

Diffusion models are powerful generative models that allow for precise control over the characteristics of the generated samples. While these diffusion models trained on large datasets have achieved success, there is often a need to…

Reinforcement learning (RL) algorithms have been used recently to align diffusion models with downstream objectives such as aesthetic quality and text-image consistency by fine-tuning them to maximize a single reward function under a fixed…

Artificial Intelligence · Computer Science 2026-03-13 Min Cheng , Fatemeh Doudi , Dileep Kalathil , Mohammad Ghavamzadeh , Panganamala R. Kumar

Diffusion models have become a central paradigm for image and multimodal generation, yet their deployment raises persistent questions about alignment, safety, preference satisfaction, and robustness to misuse. This survey reviews recent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Preeti Lamba , Kiran Ravish , Ankita Kushwaha , Pawan Kumar

We propose Diffusion-Sharpening, a fine-tuning approach that enhances downstream alignment by optimizing sampling trajectories. Existing RL-based fine-tuning methods focus on single training timesteps and neglect trajectory-level alignment,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Ye Tian , Ling Yang , Xinchen Zhang , Yunhai Tong , Mengdi Wang , Bin Cui

Diffusion models have achieved remarkable success in text-to-image generation. However, their practical applications are hindered by the misalignment between generated images and corresponding text prompts. To tackle this issue,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Zijing Hu , Fengda Zhang , Long Chen , Kun Kuang , Jiahui Li , Kaifeng Gao , Jun Xiao , Xin Wang , Wenwu Zhu

Learning from human feedback has been shown to improve text-to-image models. These techniques first learn a reward function that captures what humans care about in the task and then improve the models based on the learned reward function.…

Fine-tuning foundation models via reinforcement learning (RL) has proven promising for aligning to downstream objectives. In the case of diffusion models (DMs), though RL training improves alignment from early timesteps, critical issues…

Machine Learning · Statistics 2024-10-14 Roberto Barceló , Cristóbal Alcázar , Felipe Tobar

Denoising-based generative models, particularly diffusion and flow matching algorithms, have achieved remarkable success. However, aligning their output distributions with complex downstream objectives, such as human preferences,…

Machine Learning · Computer Science 2025-08-29 Luozhijie Jin , Zijie Qiu , Jie Liu , Zijie Diao , Lifeng Qiao , Ning Ding , Alex Lamb , Xipeng Qiu

Diffusion models are a class of flexible generative models trained with an approximation to the log-likelihood objective. However, most use cases of diffusion models are not concerned with likelihoods, but instead with downstream objectives…

Machine Learning · Computer Science 2024-01-08 Kevin Black , Michael Janner , Yilun Du , Ilya Kostrikov , Sergey Levine
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