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The purpose of the study presented herein is to develop a machine learning algorithm based on natural language processing that automatically detects whether a patient has a cardiac failure or a healthy condition by using physician notes in…

Computation and Language · Computer Science 2021-12-22 Thanh-Dung Le , Rita Noumeir , Jerome Rambaud , Guillaume Sans , Philippe Jouvet

Accurate International Classification of Diseases (ICD) coding is critical for clinical documentation, billing, and healthcare analytics, yet it remains a labour-intensive and error-prone task. Although large language models (LLMs) show…

Artificial Intelligence · Computer Science 2025-09-24 Hong-Jie Dai , Zheng-Hao Li , An-Tai Lu , Bo-Tsz Shain , Ming-Ta Li , Tatheer Hussain Mir , Kuang-Te Wang , Min-I Su , Pei-Kang Liu , Ming-Ju Tsai

Translating machine learning (ML) models effectively to clinical practice requires establishing clinicians' trust. Explainability, or the ability of an ML model to justify its outcomes and assist clinicians in rationalizing the model…

Machine Learning · Computer Science 2019-08-08 Sana Tonekaboni , Shalmali Joshi , Melissa D McCradden , Anna Goldenberg

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Clinical language processing has received a lot of attention in recent years, resulting in new models or methods for disease phenotyping, mortality prediction, and other tasks. Unfortunately, many of these approaches are tested under…

Computation and Language · Computer Science 2022-09-30 Travis R. Goodwin , Dina Demner-Fushman

In the present paper we present the potential of Explainable Artificial Intelligence methods for decision-support in medical image analysis scenarios. With three types of explainable methods applied to the same medical image data set our…

Artificial Intelligence · Computer Science 2021-05-20 Samanta Knapič , Avleen Malhi , Rohit Saluja , Kary Främling

Due to increased access to clinical trial outcomes and analysis, researchers and scientists are able to iterate or improve upon relevant approaches more effectively. However, the metrics and related results of clinical trials typically do…

Computation and Language · Computer Science 2021-01-12 Shwetha Bharadwaj , Melanie Laffin

Matching patients to clinical trials is a key unsolved challenge in bringing new drugs to market. Today, identifying patients who meet a trial's eligibility criteria is highly manual, taking up to 1 hour per patient. Automated screening is…

Computation and Language · Computer Science 2024-04-11 Michael Wornow , Alejandro Lozano , Dev Dash , Jenelle Jindal , Kenneth W. Mahaffey , Nigam H. Shah

The reuse of historical clinical trial data has significant potential to accelerate medical research and drug development. However, interoperability challenges, particularly with missing medical codes, hinders effective data integration…

Machine Learning · Computer Science 2025-03-14 Nabeel Seedat , Caterina Tozzi , Andrea Hita Ardiaca , Mihaela van der Schaar , James Weatherall , Adam Taylor

Large Language Models (LLMs) are increasingly deployed in high-stakes domains such as clinical decision support and medical documentation. However, the robustness of these models against subtle linguistic variations, specifically…

Computation and Language · Computer Science 2026-05-19 Jen-tse Huang , Didi Zhou , Faith Kamau , Amy Oh , Anne R. Links , Mark Dredze , Mary Catherine Beach , Somnath Saha

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir

Healthcare domain generates a lot of unstructured and semi-structured text. Natural Language processing (NLP) has been used extensively to process this data. Deep Learning based NLP especially Large Language Models (LLMs) such as BERT have…

Computation and Language · Computer Science 2023-01-11 Kunal Suri , Atul Singh , Prakhar Mishra , Swapna Sourav Rout , Rajesh Sabapathy

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin

Transparency in Machine Learning (ML), attempts to reveal the working mechanisms of complex models. Transparent ML promises to advance human factors engineering goals of human-centered AI in the target users. From a human-centered design…

Human-Computer Interaction · Computer Science 2022-10-03 Haomin Chen , Catalina Gomez , Chien-Ming Huang , Mathias Unberath

Natural Language Processing (NLP) systems often make use of machine learning techniques that are unfamiliar to end-users who are interested in analyzing clinical records. Although NLP has been widely used in extracting information from…

Human-Computer Interaction · Computer Science 2017-07-10 Gaurav Trivedi , Phuong Pham , Wendy Chapman , Rebecca Hwa , Janyce Wiebe , Harry Hochheiser

We are entering a hybrid era in which human developers and AI coding agents work in the same codebases. While industry practice has long optimized code for human comprehension, it is increasingly important to ensure that LLMs with different…

Software Engineering · Computer Science 2026-01-06 Markus Borg , Nadim Hagatulah , Adam Tornhill , Emma Söderberg

The design of complex engineering systems is an often long and articulated process that highly relies on engineers' expertise and professional judgment. As such, the typical pitfalls of activities involving the human factor often manifest…

Computation and Language · Computer Science 2022-11-22 Shaohong Zhong , Andrea Scarinci , Alice Cicirello

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Recent advances in large language models (LLMs) like GPT-3.5 and GPT-4 promise automation with better results and less programming, opening up new opportunities for text analysis in political science. In this study, we evaluate LLMs on…

Computation and Language · Computer Science 2024-08-29 Lorenzo Lupo , Oscar Magnusson , Dirk Hovy , Elin Naurin , Lena Wängnerud