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The purpose of the study presented herein is to develop a machine learning algorithm based on natural language processing that automatically detects whether a patient has a cardiac failure or a healthy condition by using physician notes in…
Accurate International Classification of Diseases (ICD) coding is critical for clinical documentation, billing, and healthcare analytics, yet it remains a labour-intensive and error-prone task. Although large language models (LLMs) show…
Translating machine learning (ML) models effectively to clinical practice requires establishing clinicians' trust. Explainability, or the ability of an ML model to justify its outcomes and assist clinicians in rationalizing the model…
Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…
Clinical language processing has received a lot of attention in recent years, resulting in new models or methods for disease phenotyping, mortality prediction, and other tasks. Unfortunately, many of these approaches are tested under…
In the present paper we present the potential of Explainable Artificial Intelligence methods for decision-support in medical image analysis scenarios. With three types of explainable methods applied to the same medical image data set our…
Due to increased access to clinical trial outcomes and analysis, researchers and scientists are able to iterate or improve upon relevant approaches more effectively. However, the metrics and related results of clinical trials typically do…
Matching patients to clinical trials is a key unsolved challenge in bringing new drugs to market. Today, identifying patients who meet a trial's eligibility criteria is highly manual, taking up to 1 hour per patient. Automated screening is…
The reuse of historical clinical trial data has significant potential to accelerate medical research and drug development. However, interoperability challenges, particularly with missing medical codes, hinders effective data integration…
Large Language Models (LLMs) are increasingly deployed in high-stakes domains such as clinical decision support and medical documentation. However, the robustness of these models against subtle linguistic variations, specifically…
Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…
Healthcare domain generates a lot of unstructured and semi-structured text. Natural Language processing (NLP) has been used extensively to process this data. Deep Learning based NLP especially Large Language Models (LLMs) such as BERT have…
Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…
Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…
Transparency in Machine Learning (ML), attempts to reveal the working mechanisms of complex models. Transparent ML promises to advance human factors engineering goals of human-centered AI in the target users. From a human-centered design…
Natural Language Processing (NLP) systems often make use of machine learning techniques that are unfamiliar to end-users who are interested in analyzing clinical records. Although NLP has been widely used in extracting information from…
We are entering a hybrid era in which human developers and AI coding agents work in the same codebases. While industry practice has long optimized code for human comprehension, it is increasingly important to ensure that LLMs with different…
The design of complex engineering systems is an often long and articulated process that highly relies on engineers' expertise and professional judgment. As such, the typical pitfalls of activities involving the human factor often manifest…
Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…
Recent advances in large language models (LLMs) like GPT-3.5 and GPT-4 promise automation with better results and less programming, opening up new opportunities for text analysis in political science. In this study, we evaluate LLMs on…