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The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

Doctor-patient consultations require multi-turn, context-aware communication tailored to diverse patient personas. Training or evaluating doctor LLMs in such settings requires realistic patient interaction systems. However, existing…

Artificial Intelligence · Computer Science 2025-10-30 Daeun Kyung , Hyunseung Chung , Seongsu Bae , Jiho Kim , Jae Ho Sohn , Taerim Kim , Soo Kyung Kim , Edward Choi

In recent years, neuroscience has made significant progress in building large-scale artificial neural network (ANN) models of brain activity and behavior. However, there is no consensus on the most efficient ways to collect data and design…

The complexity of modern bioinformatics analysis has created a critical gap between data generation and developing scientific insights. While large language models (LLMs) have shown promise in scientific reasoning, they remain fundamentally…

Artificial Intelligence · Computer Science 2025-10-01 Orion Li , Vinayak Agarwal , Summer Zhou , Ashwin Gopinath , Timothy Kassis

Large Vision-Language Models (LVLMs) have shown significant potential in assisting medical diagnosis by leveraging extensive biomedical datasets. However, the advancement of medical image understanding and reasoning critically depends on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Guohao Sun , Can Qin , Huazhu Fu , Linwei Wang , Zhiqiang Tao

Privacy-preserving medical decision support for kidney disease requires localized deployment of large language models (LLMs) while maintaining clinical reasoning capabilities. Current solutions face three challenges: 1) Cloud-based LLMs…

Artificial Intelligence · Computer Science 2025-03-07 Yongchao Long , Chao Yang , Gongzheng Tang , Jinwei Wang , Zhun Sui , Yuxi Zhou , Shenda Hong , Luxia Zhang

Medical education faces challenges in providing scalable, consistent clinical skills training. Simulation with standardized patients (SPs) develops communication and diagnostic skills but remains resource-intensive and variable in feedback…

Collaboration across institutional boundaries is widespread and increasing today. It depends on federations sharing data that often have governance rules or external regulations restricting their use. However, the handling of data…

Databases · Computer Science 2021-10-05 Rui Zhao , Malcolm Atkinson , Petros Papapanagiotou , Federica Magnoni , Jacques Fleuriot

Real-world mathematical modeling is inherently an experiential and collaborative endeavor. Domain experts rarely solve complex problems from scratch; instead, they draw upon analogies from historical cases and subject their hypotheses to…

Multiagent Systems · Computer Science 2026-04-03 Junhao Jia , Huangwei Chen , Ruiying Sun , Yanhui Song , Haishuai Wang , Jiajun Bu , Lei Wu

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model…

The ability to automatically generate accurate protocols for scientific experiments would represent a major step towards the automation of science. Large Language Models (LLMs) have impressive capabilities on a wide range of tasks, such as…

Computation and Language · Computer Science 2023-10-17 Odhran O'Donoghue , Aleksandar Shtedritski , John Ginger , Ralph Abboud , Ali Essa Ghareeb , Justin Booth , Samuel G Rodriques

Retrieval-Augmented Generation (RAG) is widely employed to mitigate risks such as hallucinations and knowledge obsolescence in medical question answering, yet its predominantly single-round, static retrieval paradigm misaligns with the…

Computation and Language · Computer Science 2026-05-19 Yongfeng Huang , Ruiying Chen , James Cheng

Hypothesis generation in biomedical research has traditionally centered on uncovering hidden relationships within vast scientific literature, often using methods like Literature-Based Discovery (LBD). Despite progress, current approaches…

Computation and Language · Computer Science 2025-11-13 Fuyi Yang , Chenchen Ye , Mingyu Derek Ma , Yijia Xiao , Matthew Yang , Wei Wang

The incorporation of generative artificial intelligence into personal health applications presents a transformative opportunity for personalized, data-driven health and fitness guidance, yet also poses challenges related to user safety,…

Artificial intelligence (AI) has been successfully applied in numerous scientific domains. In biomedicine, AI has already shown tremendous potential, e.g. in the interpretation of next-generation sequencing data and in the design of…

Dream narratives provide a unique window into human cognition and emotion, yet their systematic analysis using artificial intelligence has been underexplored. We introduce DreamNet, a novel deep learning framework that decodes semantic…

Machine Learning · Computer Science 2025-03-11 Tapasvi Panchagnula

AASM guidelines are the result of decades of efforts aiming at standardizing sleep scoring procedure, with the final goal of sharing a worldwide common methodology. The guidelines cover several aspects from the technical/digital…

Companies dealing with Artificial Intelligence (AI) models in Autonomous Systems (AS) face several problems, such as users' lack of trust in adverse or unknown conditions, gaps between software engineering and AI model development, and…

Software Engineering · Computer Science 2021-04-26 Silverio Martínez-Fernández , Xavier Franch , Andreas Jedlitschka , Marc Oriol , Adam Trendowicz

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant…