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The primary objective of flexibility analysis is to identify and define the feasibility region, which represents the range of operational conditions (e.g., variations in process parameters) that ensure safe, reliable, and feasible process…

Optimization and Control · Mathematics 2025-03-11 Segei Kucherenko , Nilay Shah , Oleksiy Klymenko

According to ICH Q8 guidelines, the biopharmaceutical manufacturer submits a design space (DS) definition as part of the regulatory approval application, in which case process parameter (PP) deviations within this space are not considered a…

Optimization and Control · Mathematics 2023-07-27 Thomas Oberleitner , Thomas Zahel , Christoph Herwig

A fast nonparametric procedure for classifying functional data is introduced. It consists of a two-step transformation of the original data plus a classifier operating on a low-dimensional hypercube. The functional data are first mapped…

Methodology · Statistics 2016-01-29 Karl Mosler , Pavlo Mozharovskyi

We introduce a new method of performing high dimensional discriminant analysis, which we call multiDA. We achieve this by constructing a hybrid model that seamlessly integrates a multiclass diagonal discriminant analysis model and feature…

Machine Learning · Statistics 2018-07-05 Sarah Elizabeth Romanes , John Thomas Ormerod , Jean YH Yang

This paper addresses the problem of mapping high-dimensional data to a low-dimensional space, in the presence of other known features. This problem is ubiquitous in science and engineering as there are often controllable/measurable features…

Machine Learning · Statistics 2024-01-01 Anh Tuan Bui

We introduce CODS (Computational Optimization in Design Space), a theoretical model that frames computational design as a constrained optimization problem over a structured, multi-dimensional design space. Unlike existing methods that rely…

Human-Computer Interaction · Computer Science 2025-06-24 Nan Cao , Xiaoyu Qi , Chuer Chen , Xiaoke Yan

Unsupervised dimension selection is an important problem that seeks to reduce dimensionality of data, while preserving the most useful characteristics. While dimensionality reduction is commonly utilized to construct low-dimensional…

Machine Learning · Statistics 2018-11-01 Jayaraman J. Thiagarajan , Rushil Anirudh , Rahul Sridhar , Peer-Timo Bremer

This paper develops the concept of the Adjacent Deviation Subspace (ADS), a novel framework for reducing infinite-dimensional functional data into finite-dimensional vector or scalar representations while preserving critical information of…

Methodology · Statistics 2025-06-19 Luoyao Yu , Long Feng , Xuehu Zhu

Dynamical Systems (DS) are an effective and powerful means of shaping high-level policies for robotics control. They provide robust and reactive control while ensuring the stability of the driving vector field. The increasing complexity of…

Robotics · Computer Science 2024-03-19 Bernardo Fichera , Aude Billard

An adaptation of Response Surface Methodology (RSM) when the covariate is of high or infinite dimensional is proposed, providing a tool for black-box optimization in this context. We combine dimension reduction techniques with classical…

Statistics Theory · Mathematics 2015-11-19 Angelina Roche

Data are not only ubiquitous in society, but are increasingly complex both in size and dimensionality. Dimension reduction offers researchers and scholars the ability to make such complex, high dimensional data spaces simpler and more…

Machine Learning · Computer Science 2021-03-15 Philip D. Waggoner

Diagrammatic reasoning (DR) is pervasive in human problem solving as a powerful adjunct to symbolic reasoning based on language-like representations. The research reported in this paper is a contribution to building a general purpose DR…

Artificial Intelligence · Computer Science 2014-01-17 Bonny Banerjee , B. Chandrasekaran

The rapidly evolving field of engineering design of functional surfaces necessitates sophisticated tools to manage the inherent complexity of high-dimensional design spaces. This survey paper offers a scoping review, i.e., a literature…

Optimization and Control · Mathematics 2025-04-09 Andrea Serani , Matteo Diez

Design space exploration (DSE) plays a crucial role in enabling custom hardware architectures, particularly for emerging applications like AI, where optimized and specialized designs are essential. With the growing complexity of deep neural…

Machine Learning · Computer Science 2025-01-20 Jamin Seo , Akshat Ramachandran , Yu-Chuan Chuang , Anirudh Itagi , Tushar Krishna

Machine vision and image processing are often used with sensors for situation awareness in autonomous systems, from industrial robots to self-driving cars. The 3D depth sensors, such as LiDAR (Light Detection and Ranging), Radar, are great…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 MA Muktadir , Sydney Parker , Sun Yi

The geometric design of structures with optimized physical and chemical properties is one of the core topics in materials science. However, designing new functional materials is challenging due to the vast number of existing and the…

Optics · Physics 2025-07-17 Congcong Cui , Guangfeng Wei , Matthias Saba , Yuanyuan Cao , Lu Han

The $DD\alpha$-classifier, a nonparametric fast and very robust procedure, is described and applied to fifty classification problems regarding a broad spectrum of real-world data. The procedure first transforms the data from their original…

Applications · Statistics 2022-11-10 Pavlo Mozharovskyi , Karl Mosler , Tatjana Lange

Following the seminal idea of Tukey, data depth is a function that measures how close an arbitrary point of the space is located to an implicitly defined center of a data cloud. Having undergone theoretical and computational developments,…

Computation · Statistics 2016-08-16 Oleksii Pokotylo , Pavlo Mozharovskyi , Rainer Dyckerhoff

A first order inference system, called R-calculus, is defined to develop the specifications. It is used to eliminate the laws which is not consistent with the user's requirements. The R-calculus consists of the structural rules, an axiom, a…

Logic in Computer Science · Computer Science 2007-05-23 Wei Li

In recent years, manifold methods have moved into focus as tools for dimension reduction. Assuming that the high-dimensional data actually lie on or close to a low-dimensional nonlinear manifold, these methods have shown convincing results…

Machine Learning · Statistics 2020-12-23 Moritz Herrmann , Fabian Scheipl
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