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We propose a scheme for global optimization with first-principles energy expressions (GOFEE) of atomistic structure. While unfolding its search, the method actively learns a surrogate model of the potential energy landscape on which it…

Chemical Physics · Physics 2020-03-04 Malthe K. Bisbo , Bjørk Hammer

Global Optimization with First-principles Energy Expressions (GOFEE) is an efficient method for identifying low energy structures in computationally expensive energy landscapes such as the ones described by density functional theory (DFT),…

Chemical Physics · Physics 2023-07-06 Malthe K. Bisbo , Bjørk Hammer

Tackling molecular optimization problems using conventional computational methods is challenging, because the determination of the optimized configuration is known to be an NP-hard problem. Recently, there has been increasing interest in…

Applied Physics · Physics 2021-08-24 Eshan Joshi , Samuel Somuyiwa , Hossein Z. Jooya

Optimization of atomic structures presents a challenging problem, due to their highly rough and non-convex energy landscape, with wide applications in the fields of drug design, materials discovery, and mechanics. Here, we present a graph…

Machine Learning · Computer Science 2023-06-21 Vaibhav Bihani , Sahil Manchanda , Srikanth Sastry , Sayan Ranu , N. M. Anoop Krishnan

We introduce a computational method for global optimization of structure and ordering in atomic systems. The method relies on interpolation between chemical elements, which is incorporated in a machine learning structural fingerprint. The…

Materials Science · Physics 2021-10-18 Sami Kaappa , Casper Larsen , Karsten Wedel Jacobsen

This paper presents a fast method for global search of atomic structures at ab initio level. The structures global optimization (SGO) engine consists of a high-efficiency differential evolution algorithm, accelerated local relaxation…

Materials Science · Physics 2017-09-13 Zhanghui Chen , Weile Jia , Lin-Wang Wang

In this paper, we propose a graph classification approach for automatically determining whether to use a monolithic or a decomposition-based solution method. In this approach, an optimization problem is represented as a graph that captures…

Optimization and Control · Mathematics 2023-10-12 Ilias Mitrai , Prodromos Daoutidis

A new graph-based order parameter is introduced for the characterization of atomistic structures. The order parameter is universal to any material/chemical system, and is transferable to all structural geometries. Three sets of data are…

Materials Science · Physics 2022-03-22 James Chapman , Nir Goldman , Brandon Wood

Advanced structure prediction methods developed over the past decades include an unorthodox strategy of allowing atoms to displace into extra dimensions. A recently implemented global optimization of structures from hyperspace (GOSH) has…

Materials Science · Physics 2025-07-21 Daviti Gochitashvili , Maxwell Meyers , Cindy Wang , Aleksey N. Kolmogorov

Crystal structure prediction algorithms have become powerful tools for materials discovery in recent years, however, they are usually limited to relatively small systems. The main challenge is that the number of local minima grows…

Materials Science · Physics 2022-02-09 Hao Gao , Junjie Wang , Yu Han , Jian Sun

ClasSOMfier is a software package to classify atoms into a given number of disconnected groups (or clusters) and detect lattice defects, such as vacancies, interstitials, dislocations, voids and grain boundaries. Each cluster is formed by…

Atomic and Molecular Clusters · Physics 2021-01-27 Javier F. Troncoso

In this paper, we propose a design methodology for one-class classifiers using an ensemble-of-classifiers approach. The objective is to select the best structures created during the training phase using an ensemble of spanning trees. It…

Machine Learning · Computer Science 2019-09-11 Riccardo La Grassa , Ignazio Gallo , Alessandro Calefati , Dimitri Ognibene

A local optimization method based on Bayesian Gaussian Processes is developed and applied to atomic structures. The method is applied to a variety of systems including molecules, clusters, bulk materials, and molecules at surfaces. The…

Computational Physics · Physics 2019-09-11 Estefanía Garijo del Río , Jens Jørgen Mortensen , Karsten W. Jacobsen

The automatic analysis of chemical literature has immense potential to accelerate the discovery of new materials and drugs. Much of the critical information in patent documents and scientific articles is contained in figures, depicting the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Lucas Morin , Martin Danelljan , Maria Isabel Agea , Ahmed Nassar , Valery Weber , Ingmar Meijer , Peter Staar , Fisher Yu

We introduce a method for global optimization of the structure of atomic systems that uses additional atoms with fractional existence. The method allows for movement of atoms over long distances bypassing energy barriers encountered in the…

The identification of low-energy conformers for a given molecule is a fundamental problem in computational chemistry and cheminformatics. We assess here a conformer search that employs a genetic algorithm for sampling the low-energy segment…

Biomolecules · Quantitative Biology 2015-11-24 Adriana Supady , Volker Blum , Carsten Baldauf

We consider the problem of computing a lightest derivation of a global structure using a set of weighted rules. A large variety of inference problems in AI can be formulated in this framework. We generalize A* search and heuristics derived…

Artificial Intelligence · Computer Science 2011-10-12 P. F. Felzenszwalb , D. McAllester

Disordered materials such as glasses, unlike crystals, lack long range atomic order and have no periodic unit cells, yielding a high dimensional configuration space with widely varying properties. The complexity not only increases…

Computational Engineering, Finance, and Science · Computer Science 2025-11-12 Qiyuan Chen , Ajay Annamareddy , Ying-Fei Li , Dane Morgan , Bu Wang

We here introduce a novel classification approach adopted from the nonlinear model identification framework, which jointly addresses the feature selection and classifier design tasks. The classifier is constructed as a polynomial expansion…

Machine Learning · Computer Science 2016-07-29 Aida Brankovic , Alessandro Falsone , Maria Prandini , Luigi Piroddi

We show how to speed up global optimization of molecular structures using machine learning methods. To represent the molecular structures we introduce the auto-bag feature vector that combines: i) a local feature vector for each atom, ii)…

Computational Physics · Physics 2018-10-10 Søren A. Meldgaard , Esben L. Kolsbjerg , Bjørk Hammer
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