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We build and study an individual based model of the telomere length's evolution in a population across multiple generations. This model is a continuous time typed branching process, where the type of an individual includes its gamete mean…

Populations and Evolution · Quantitative Biology 2023-11-17 Athanasios Benetos , Olivier Coudray , Anne Gégout-Petit , Lionel Lenôtre , Simon Toupance , Denis Villemonais

Predicting the ancestral sequences of a group of homologous sequences related by a phylogenetic tree has been the subject of many studies, and numerous methods have been proposed to this purpose. Theoretical results are available that show…

Populations and Evolution · Quantitative Biology 2013-09-05 Olivier Gascuel , Mike Steel

It is possible to consider stochastic models of sequence evolution in phylogenetics in the context of a dynamical tensor description inspired from physics. Approaching the problem in this framework allows for the well developed methods of…

Populations and Evolution · Quantitative Biology 2007-05-23 J. G. Sumner , P. D. Jarvis

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

Populations and Evolution · Quantitative Biology 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

Using a population dynamics inspired by an ensemble of growing cells, a set of fluctuation theorems linking observables measured at the lineage and population levels are derived. One of these relations implies specific inequalities…

Populations and Evolution · Quantitative Biology 2021-11-08 Reinaldo García-García , Arthur Genthon , David Lacoste

Cancers follow a clonal Darwinian evolution, with fitter subclones replacing more quiescent cells, ultimately giving rise to macroscopic disease. High-throughput genomics provides the opportunity to investigate these processes and determine…

Quantitative Methods · Quantitative Biology 2014-10-07 Sakellarios Zairis , Hossein Khiabanian , Andrew J. Blumberg , Raul Rabadan

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees. Substitutions in sequences are modelled through a continuous-time Markov process, characterised by an instantaneous rate matrix, which standard…

Populations and Evolution · Quantitative Biology 2020-07-20 Naomi E. Hannaford , Sarah E. Heaps , Tom M. W. Nye , Tom A. Williams , T. Martin Embley

In biology, a phylogenetic tree is a tool to represent the evolutionary relationship between species. Unfortunately, the classical Schr\"oder tree model is not adapted to take into account the chronology between the branching nodes. In…

Data Structures and Algorithms · Computer Science 2019-01-15 Olivier Bodini , Antoine Genitrini , Mehdi Naima

We are interested in the evolving genealogy of a birth and death process with trait structure and ecological interactions. Traits are hereditarily transmitted from a parent to its offspring unless a mutation occurs. The dynamics may depend…

Probability · Mathematics 2012-06-20 Sylvie Méléard , Viet Chi Tran

We define symmetric and asymmetric branching trees, a class of processes particularly suited for modeling genealogies of inhomogeneous populations where individuals may reproduce throughout life. In this framework, a broad class of…

Probability · Mathematics 2025-10-10 Frederik M. Andersen , Marc A. Suchard , Carsten Wiuf , Samir Bhatt

The forest of mutations associated to a multitype branching forest is obtained by merging together all vertices of its clusters and by preserving connections between them. We first show that the forest of mutations of any mulitype branching…

Probability · Mathematics 2015-10-06 Loïc Chaumont , Thi Ngoc Anh Nguyen

We consider catalytic branching populations. They consist of a catalyst population evolving according to a critical binary branching process in continuous time with a constant branching rate and a reactant population with a branching rate…

Probability · Mathematics 2009-09-29 Andreas Greven , Lea Popovic , Anita Winter

In this paper, we review recent results of ours concerning branching processes with general lifetimes and neutral mutations, under the infinitely many alleles model, where mutations can occur either at birth of individuals or at a constant…

Probability · Mathematics 2012-11-29 Nicolas Champagnat , Amaury Lambert , Mathieu Richard

A dynamical picture of phylogenetic evolution is given in terms of Markov models on a state space, comprising joint probability distributions for character types of taxonomic classes. Phylogenetic branching is a process which augments the…

Populations and Evolution · Quantitative Biology 2009-11-10 P. D. Jarvis , J. D. Bashford , J. G. Sumner

Stochastic models, based on random processes, may lead to power law distributions, which provide long range correlations. The observation of power law behavior and the presence of long range correlations in biological systems has been…

Statistical Mechanics · Physics 2008-03-26 Thomas Oikonomou

Recently, much attention has been given to understanding recombination events along a chromosome in a variety of field. For instance, many population genetics problems are limited by the inaccuracy of inferred evolutionary histories of…

Quantitative Methods · Quantitative Biology 2017-10-31 Jacqueline Kane , Joseph Rusinko , Katherine Thompson

We prove the existence of the total length process for the genealogical tree of a population model with random size given by a quadratic stationary continuous-state branching processes. We also give, for the one-dimensional marginal, its…

Probability · Mathematics 2014-07-18 Hongwei Bi , Jean-François Delmas

We derive the asymptotic behavior of the total, active and inactive branch lengths of the seed bank coalescent, when the size of the initial sample grows to infinity. Those random variables have important applications for populations…

Probability · Mathematics 2020-09-28 Adrián González Casanova , Lizbeth Peñaloza , Arno Siri-Jégousse

Using a simple model with link removals as well as link additions, we show that an evolving network is scale free with a degree exponent in the range of (2, 4]. We then establish a relation between the network evolution and a set of…

Mathematical Physics · Physics 2007-05-23 Dinghua Shi , Liming Liu , Xiang Zhu , Huijie Zhou , Binbin Wang

Forward-time models of diversification (i.e., speciation and extinction) produce phylogenetic trees that grow "vertically" as time goes by. Pruning the extinct lineages out of such trees leads to natural models for reconstructed trees…

Populations and Evolution · Quantitative Biology 2013-08-07 Amaury Lambert , Tanja Stadler