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The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

Large Language Models (LLMs) have demonstrated remarkable potential in code generation. The integration of Chain of Thought (CoT) reasoning can further boost their performance. However, current CoT methods often require manual writing or…

Software Engineering · Computer Science 2024-08-06 Guang Yang , Yu Zhou , Xiang Chen , Xiangyu Zhang , Terry Yue Zhuo , Taolue Chen

In the past decade a surge in the amount of electronic health record (EHR) data in the United States, attributed to a favorable policy environment created by the Health Information Technology for Economic and Clinical Health (HITECH) Act of…

Computation and Language · Computer Science 2025-12-08 Ivan Makohon , Mohamad Najafi , Jian Wu , Mathias Brochhausen , Yaohang Li

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Recent advances in large language models (LLMs) have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored. This study…

Computation and Language · Computer Science 2025-09-08 Maya Kruse , Shiyue Hu , Nicholas Derby , Yifu Wu , Samantha Stonbraker , Bingsheng Yao , Dakuo Wang , Elizabeth Goldberg , Yanjun Gao

Drug toxicity remains a major challenge in pharmaceutical development. Recent machine learning models have improved in silico toxicity prediction, but their reliance on annotated data and lack of interpretability limit their applicability.…

Machine Learning · Computer Science 2025-11-06 Jueon Park , Yein Park , Minju Song , Soyon Park , Donghyeon Lee , Seungheun Baek , Jaewoo Kang

Large language models (LLMs) are increasingly used to extract clinical data from electronic health records (EHRs), offering significant improvements in scalability and efficiency for real-world data (RWD) curation in oncology. However, the…

Detecting texts generated by Large Language Models (LLMs) could cause grave mistakes due to incorrect decisions, such as undermining students' academic dignity. LLM text detection thus needs to ensure the interpretability of the decision,…

Computation and Language · Computer Science 2026-05-06 Ryuto Koike , Masahiro Kaneko , Ayana Niwa , Preslav Nakov , Naoaki Okazaki

Log data provides crucial insights for tasks like monitoring, root cause analysis, and anomaly detection. Due to the vast volume of logs, automated log parsing is essential to transform semi-structured log messages into structured…

Machine Learning · Computer Science 2025-05-16 Viktor Beck , Max Landauer , Markus Wurzenberger , Florian Skopik , Andreas Rauber

Recent studies have demonstrated promising performance of ChatGPT and GPT-4 on several medical domain tasks. However, none have assessed its performance using a large-scale real-world electronic health record database, nor have evaluated…

Computation and Language · Computer Science 2023-07-18 Jingqing Zhang , Kai Sun , Akshay Jagadeesh , Mahta Ghahfarokhi , Deepa Gupta , Ashok Gupta , Vibhor Gupta , Yike Guo

The integration of Large Language Models (LLMs) into clinical decision support is critically obstructed by their opaque and often unreliable reasoning. In the high-stakes domain of healthcare, correct answers alone are insufficient;…

Artificial Intelligence · Computer Science 2026-04-21 Chen Zhan , Xiaoyu Tan , Gengchen Ma , Yu-Jie Xiong , Xiaoyan Jiang , Xihe Qiu

The rise of Large Language Models (LLMs), such as LLaMA and ChatGPT, has opened new opportunities for enhancing recommender systems through improved explainability. This paper provides a systematic literature review focused on leveraging…

Information Retrieval · Computer Science 2025-01-22 Alan Said

Cognitive Diagnosis Models (CDMs) are designed to assess students' cognitive states by analyzing their performance across a series of exercises. However, existing CDMs often struggle with diagnosing infrequent students and exercises due to…

Artificial Intelligence · Computer Science 2025-02-11 Zhiang Dong , Jingyuan Chen , Fei Wu

Clinical decision-making is inherently complex and fast-paced, particularly in emergency departments (EDs) where critical, rapid and high-stakes decisions are made. Clinical Decision Rules (CDRs) are standardized evidence-based tools that…

A knowledge gap persists between machine learning (ML) developers (e.g., data scientists) and practitioners (e.g., clinicians), hampering the full utilization of ML for clinical data analysis. We investigated the potential of the ChatGPT…

Code translation aims to convert source code from one programming language (PL) to another. Given the promising abilities of large language models (LLMs) in code synthesis, researchers are exploring their potential to automate code…

The breakthrough of OpenAI o1 highlights the potential of enhancing reasoning to improve LLM. Yet, most research in reasoning has focused on mathematical tasks, leaving domains like medicine underexplored. The medical domain, though…

Computation and Language · Computer Science 2024-12-30 Junying Chen , Zhenyang Cai , Ke Ji , Xidong Wang , Wanlong Liu , Rongsheng Wang , Jianye Hou , Benyou Wang

Accurate clinical coding is essential for healthcare documentation, billing, and decision-making. While prior work shows that off-the-shelf LLMs struggle with this task, evaluations based on exact match metrics often overlook errors where…

Computation and Language · Computer Science 2025-10-10 Zhangdie Yuan , Han-Chin Shing , Mitch Strong , Chaitanya Shivade

Many reasoning, planning, and problem-solving tasks share an intrinsic algorithmic nature: correctly simulating each step is a sufficient condition to solve them correctly. This work studies to what extent Large Language Models (LLMs) can…

Large language models (LLMs) have become vital tools for software development, but they often require verbose intermediate reasoning for complex code tasks, leading to high latency and costs. This research extends the Chain of Draft (CoD)…

Software Engineering · Computer Science 2025-06-16 Shaoyi Yang
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