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Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

Deep Neural Networks (DNNs) show a significant impact on medical imaging. One significant problem with adopting DNNs for skin cancer classification is that the class frequencies in the existing datasets are imbalanced. This problem hinders…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Ibrahim Saad Ali , Mamdouh Farouk Mohamed , Yousef Bassyouni Mahdy

Drug overdose remains a critical global health issue, often driven by misuse of opioids, painkillers, and psychiatric medications. Traditional research methods face limitations, whereas social media offers real-time insights into…

Computation and Language · Computer Science 2025-07-16 Muhammad Ahmad , Fida Ullah , Muhammad Usman , Umyh Habiba , ldar Batyrshin , Grigori Sidorov

The escalating prevalence of cannabis use, and associated cannabis-use disorder (CUD), poses a significant public health challenge globally. With a notably wide treatment gap, especially among emerging adults (EAs; ages 18-25), addressing…

Artificial Intelligence · Computer Science 2024-06-12 Susobhan Ghosh , Yongyi Guo , Pei-Yao Hung , Lara Coughlin , Erin Bonar , Inbal Nahum-Shani , Maureen Walton , Susan Murphy

Substance use disorders (SUDs) are a growing concern globally, necessitating enhanced understanding of the problem and its trends through data-driven research. Social media are unique and important sources of information about SUDs,…

Computation and Language · Computer Science 2024-05-13 Yao Ge , Sudeshna Das , Karen O'Connor , Mohammed Ali Al-Garadi , Graciela Gonzalez-Hernandez , Abeed Sarker

The utility of tabular data for tasks ranging from model training to large-scale data analysis is often constrained by privacy concerns or regulatory hurdles. While existing data generation methods, particularly those based on Generative…

Machine Learning · Computer Science 2025-10-29 Tu Anh Hoang Nguyen , Dang Nguyen , Tri-Nhan Vo , Thuc Duy Le , Sunil Gupta

We introduce a new problem in unsupervised domain adaptation, termed as Generalized Universal Domain Adaptation (GUDA), which aims to achieve precise prediction of all target labels including unknown categories. GUDA bridges the gap between…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Didi Zhu , Yinchuan Li , Yunfeng Shao , Jianye Hao , Fei Wu , Kun Kuang , Jun Xiao , Chao Wu

Recent advances in conditional generative modeling have introduced Continuous conditional Generative Adversarial Network (CcGAN) and Continuous Conditional Diffusion Model (CCDM) for estimating high-dimensional data distributions…

Machine Learning · Computer Science 2026-02-04 Xin Ding , Yun Chen , Yongwei Wang , Kao Zhang , Sen Zhang , Peibei Cao , Xiangxue Wang

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

The task of weed detection is an essential element of precision agriculture since accurate species identification allows a farmer to selectively apply herbicides and fits into sustainable agriculture crop management. This paper proposes a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Pandiyaraju V , Abishek Karthik , Sreya Mynampati , Poovarasan L , D. Saraswathi

In standard generative deep learning models, such as autoencoders or GANs, the size of the parameter set is proportional to the complexity of the generated data distribution. A significant challenge is to deploy resource-hungry deep…

Machine Learning · Computer Science 2021-10-29 Shreshth Tuli , Shikhar Tuli , Giuliano Casale , Nicholas R. Jennings

Traditional drug design faces significant challenges due to inherent chemical and biological complexities, often resulting in high failure rates in clinical trials. Deep learning advancements, particularly generative models, offer potential…

Quantitative Methods · Quantitative Biology 2025-08-27 Mahsa Sheikholeslami , Navid Mazrouei , Yousof Gheisari , Afshin Fasihi , Matin Irajpour , Ali Motahharynia

Unsupervised Domain Adaptation (UDA) aims at classifying unlabeled target images leveraging source labeled ones. In this work, we consider the Partial Domain Adaptation (PDA) variant, where we have extra source classes not present in the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Tiago Salvador , Kilian Fatras , Ioannis Mitliagkas , Adam Oberman

Table Structure Recognition is an essential part of end-to-end tabular data extraction in document images. The recent success of deep learning model architectures in computer vision remains to be non-reflective in table structure…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Umar Khan , Sohaib Zahid , Muhammad Asad Ali , Adnan ul Hassan , Faisal Shafait

With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…

Genomics · Quantitative Biology 2022-04-14 Attayeb Mohsen , Lokesh P. Tripathi , Kenji Mizuguchi

Background: Computational drug repurposing is a cost- and time-efficient approach that aims to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It is especially critical for emerging and/or orphan…

Quantitative Methods · Quantitative Biology 2023-04-26 Chunyu Ma , Zhihan Zhou , Han Liu , David Koslicki

People with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring the progression of the disease through a…

Audio and Speech Processing · Electrical Eng. & Systems 2022-05-25 Mohammadreza Iman , Amy Giuntini , Hamid Reza Arabnia , Khaled Rasheed

Generative models for tabular data have evolved rapidly beyond Generative Adversarial Networks (GANs). While GANs pioneered synthetic tabular data generation, recent advances in diffusion models and large language models (LLMs) have opened…

Machine Learning · Computer Science 2026-04-10 Insaf Ashrapov

To understand how genetic variants in human genomes manifest in phenotypes -- traits like height or diseases like asthma -- geneticists have sequenced and measured hundreds of thousands of individuals. Geneticists use this data to build…

Machine Learning · Computer Science 2025-07-01 Alan N. Amin , Andres Potapczynski , Andrew Gordon Wilson

Drug addiction or drug overdose is a global public health crisis, and the design of anti-addiction drugs remains a major challenge due to intricate mechanisms. Since experimental drug screening and optimization are too time-consuming and…

Biomolecules · Quantitative Biology 2022-12-06 Zhu Zailiang , Dou Bozheng , Cao Yukang , Jiang Jian , Zhu Yueying , Chen Dong , Feng Hongsong , Liu Jie , Zhang Bengong , Zhou Tianshou , Wei Guowei
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