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Physics-Informed Neural Network (PINN) is a deep learning framework that integrates the governing equations underlying data into a loss function. In this study, we consider the problem of estimating state variables and parameters in…

Symbolic Computation · Computer Science 2025-08-07 Mizuka Komatsu

Compartmental models provide simple and efficient tools to analyze the relevant transmission processes during an outbreak, to produce short-term forecasts or transmission scenarios, and to assess the impact of vaccination campaigns.…

Numerical Analysis · Mathematics 2025-02-19 Caterina Millevoi , Damiano Pasetto , Massimiliano Ferronato

Physics-informed neural networks (PINNs) constitute a flexible approach to both finding solutions and identifying parameters of partial differential equations. Most works on the topic assume noiseless data, or data contaminated with weak…

Machine Learning · Statistics 2024-06-21 Philipp Pilar , Niklas Wahlström

A variety of approaches using compartmental models have been used to study the COVID-19 pandemic and the usage of machine learning methods with these models has had particularly notable success. We present here an approach toward analyzing…

Populations and Evolution · Quantitative Biology 2022-08-19 Haoran Hu , Connor M Kennedy , Panayotis G. Kevrekidis , Hongkun Zhang

We develop a physics-informed neural network (PINN) framework for parameter estimation in fractional-order SEIRD epidemic models. By embedding the Caputo fractional derivative into the network residuals via the L1 discretization scheme, our…

Machine Learning · Statistics 2025-09-30 Achraf Zinihi

Accurate forecasting of contagious diseases is critical for public health policymaking and pandemic preparedness. We propose a new infectious disease forecasting model based on physics-informed neural networks (PINNs), an emerging…

Machine Learning · Computer Science 2025-04-30 Ying Qian , Kui Zhang , Éric Marty , Avranil Basu , Eamon B. O'Dea , Xianqiao Wang , Spencer Fox , Pejman Rohani , John M. Drake , He Li

This work introduces a physics-informed neural networks (PINNs)-based model predictive control (MPC) framework for susceptible-infected-recovered ($SIR$) spreading models. Existing studies in MPC design for epidemic control often assume…

Machine Learning · Computer Science 2025-09-17 Aiping Zhong , Baike She , Philip E. Paré

We introduce EINNs, a framework crafted for epidemic forecasting that builds upon the theoretical grounds provided by mechanistic models as well as the data-driven expressibility afforded by AI models, and their capabilities to ingest…

Machine Learning · Computer Science 2023-01-12 Alexander Rodríguez , Jiaming Cui , Naren Ramakrishnan , Bijaya Adhikari , B. Aditya Prakash

A physics-informed neural network (PINN) embedded with the susceptible-infected-removed (SIR) model is devised to understand the temporal evolution dynamics of infectious diseases. Firstly, the effectiveness of this approach is demonstrated…

Quantitative Methods · Quantitative Biology 2025-04-08 Shuai Han , Lukas Stelz , Horst Stoecker , Lingxiao Wang , Kai Zhou

Physics-informed neural networks (PINNs) have demonstrated promise as a framework for solving forward and inverse problems involving partial differential equations. Despite recent progress in the field, it remains challenging to quantify…

Machine Learning · Computer Science 2025-11-14 Bruno Jacob , Ashish S. Nair , Amanda A. Howard , Jan Drgona , Panos Stinis

Inferring biophysical parameters and hidden state variables from partial and noisy observations is a fundamental challenge in computational neuroscience. This problem is particularly difficult for fast - slow spiking and bursting models,…

Neural and Evolutionary Computing · Computer Science 2026-03-11 Changliang Wei , Yangyang Wang , Xueyu Zhu

In chemical engineering, process data are expensive to acquire, and complex phenomena are difficult to fully model. We explore the use of physics-informed neural networks (PINNs) for modeling dynamic processes with incomplete mechanistic…

Machine Learning · Computer Science 2024-10-01 Mehmet Velioglu , Song Zhai , Sophia Rupprecht , Alexander Mitsos , Andreas Jupke , Manuel Dahmen

When investigating epidemic dynamics through differential models, the parameters needed to understand the phenomenon and to simulate forecast scenarios require a delicate calibration phase, often made even more challenging by the scarcity…

Numerical Analysis · Mathematics 2023-09-11 Giulia Bertaglia , Chuan Lu , Lorenzo Pareschi , Xueyu Zhu

In this work, we present an approach called Disease Informed Neural Networks (DINNs) that can be employed to effectively predict the spread of infectious diseases. This approach builds on a successful physics informed neural network…

Machine Learning · Computer Science 2022-08-26 Sagi Shaier , Maziar Raissi , Padmanabhan Seshaiyer

Vector-borne diseases continue to pose a significant health threat globally with more than 3 billion people at risk each year. Despite some limitations, mechanistic dynamic models are a popular approach to representing biological processes…

Data-driven deep learning provides efficient algorithms for parameter identification of epidemiology models. Unlike the constant parameters, the complexity of identifying time-varying parameters is largely increased. In this paper, a…

Dynamical Systems · Mathematics 2021-03-19 Jie Long , Abdul Khaliq , Khaled Furati

Exponential-family random network (ERN) models specify a joint representation of both the dyads of a network and nodal characteristics. This class of models allow the nodal characteristics to be modelled as stochastic processes, expanding…

Methodology · Statistics 2013-03-07 Ian E. Fellows , Mark S. Handcock

Physics-informed neural networks (PINNs) have emerged as a powerful tool for solving inverse problems, especially in cases where no complete information about the system is known and scatter measurements are available. This is especially…

Computational Engineering, Finance, and Science · Computer Science 2023-08-03 Jeremias Garay , Jocelyn Dunstan , Sergio Uribe , Francisco Sahli Costabal

We present the fundamental theory and implementation guidelines underlying Evidential Physics-Informed Neural Network (E-PINN) -- a novel class of uncertainty-aware PINN. It leverages the marginal distribution loss function of evidential…

Machine Learning · Computer Science 2025-12-09 Hai Siong Tan , Kuancheng Wang , Rafe McBeth

Physics-informed neural networks (PINNs) are an influential method of solving differential equations and estimating their parameters given data. However, since they make use of neural networks, they provide only a point estimate of…

Machine Learning · Computer Science 2024-05-15 Lena Podina , Mahdi Torabi Rad , Mohammad Kohandel
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